ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

PPP2R5C

Full Name:

protein phosphatase 2, regulatory subunit B', gamma isoform

Alias:

B56G|MGC23064|PR61G

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

14q32

Physical Location:

101345924-101463830 on NC_000014.7

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

U37352

Dataset Information

Name:		12065639
Method:		Microarray
Tissue:		Frontal and motor cortices
Phenotype:		Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:		Mayfield et al. J Neurochem. (2002) Patterns of gene expression are altered in the frontal and motor cortices of human alcoholics. PubMed
Summary:		We used cDNA microarrays to analyze expression of approximately 10 000 genes in the frontal and motor cortices of three groups of chronic alcoholic and matched control cases. Fluorescent intensity ratios of 1.4-fold or greater in either direction (representing the 99% confidence interval) were used to indicate differentially expressed genes.

Gene Refseq Sequence Annotation

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0000159	protein phosphatase type 2A complex	Cellular Component	IEA
GO:0000159	protein phosphatase type 2A complex	Cellular Component	NAS (8703017)
GO:0005634	nucleus	Cellular Component	IDA (8703017)
GO:0016021	integral to membrane	Cellular Component	IDA (12297508)
GO:0005488	binding	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IPI (8617797\|15380617\|17540176)
GO:0008601	protein phosphatase type 2A regulator activity	Molecular Function	NAS (8703017)
GO:0008233	peptidase activity	Molecular Function	IDA (12297508)
GO:0008601	protein phosphatase type 2A regulator activity	Molecular Function	IEA
GO:0007165	signal transduction	Biological Process	NAS (8703017)
GO:0007165	signal transduction	Biological Process	IEA
GO:0016485	protein processing	Biological Process	IDA (12297508)