ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

PRKCA

Full Name:

protein kinase C, alpha

Alias:

AAG6|MGC129900|MGC129901|PKC-alpha|PKCA|PRKACA

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

17q22-q23.2

Physical Location:

61729387-62237323 on NC_000017.9

Gene Type:

protein-coding

Orthologs:

This gene has Rat: 24680 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

PRKCA

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_002737.2	NP_002728.1	NC_000017.9 range: 61729387..62237323

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005886	plasma membrane	Cellular Component	EXP (9814702\|10194441\|10856305)
GO:0005624	membrane fraction	Cellular Component	IDA (17983652)
GO:0005829	cytosol	Cellular Component	EXP (9814702)
GO:0005829	cytosol	Cellular Component	IDA (17983652)
GO:0019992	diacylglycerol binding	Molecular Function	IEA
GO:0016740	transferase activity	Molecular Function	IEA
GO:0008270	zinc ion binding	Molecular Function	IEA
GO:0000166	nucleotide binding	Molecular Function	IEA
GO:0005524	ATP binding	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IPI (12893243)
GO:0005509	calcium ion binding	Molecular Function	IEA
GO:0004697	protein kinase C activity	Molecular Function	TAS (3755548)
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0006468	protein amino acid phosphorylation	Biological Process	IEA
GO:0007166	cell surface receptor linked signal transduction	Biological Process	NR
GO:0007242	intracellular signaling cascade	Biological Process	IEA
GO:0008624	induction of apoptosis by extracellular signals	Biological Process	TAS (10825394)