ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Olfm1

Full Name:

olfactomedin 1

Alias:

AMY|AW742568|Noe1|OlfA|Pancortin|Pancortin3

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

2 A3

Physical Location:

28048612-28086255 on NC_000068.6

Gene Type:

protein-coding

Human Ortholog:

GeneID: 10439 Symbol (Name): OLFM1 (olfactomedin 1)

Ortholog Status:

The human GeneID 10439 is also in human dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		Olfm1
Original ID2:		D78265

Dataset Information

Name:		15745951
Method:		Microarray
Tissue:		Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:		Acute ethanol response
Publication:		Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:		The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.

Gene Refseq Sequence Annotation

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005615	extracellular space	Cellular Component	IDA (15927402)
GO:0005615	extracellular space	Cellular Component	RCA (12466851)
GO:0005783	endoplasmic reticulum	Cellular Component	IEA
GO:0016020	membrane	Cellular Component	IEA
GO:0005515	protein binding	Molecular Function	IPI (15927402)
GO:0016524	latrotoxin receptor activity	Molecular Function	IEA
GO:0007275	multicellular organismal development	Biological Process	IEA
GO:0051259	protein oligomerization	Biological Process	IDA (15927402)