ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Ensa

Full Name:

endosulfine alpha

Alias:

1700020C18Rik|2610007F17Rik|AI451924

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

3 F2.1

Physical Location:

95428901-95436038 on NC_000069.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 2029 Symbol (Name): ENSA (endosulfine alpha)

Ortholog Status:

The human GeneID 2029 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		Ensa
Original ID2:		AJ005985

Dataset Information

Name:		15745951
Method:		Microarray
Tissue:		Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:		Acute ethanol response
Publication:		Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:		The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.

Gene Refseq Sequence Annotation

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005737	cytoplasm	Cellular Component	ISO
GO:0005102	receptor binding	Molecular Function	ISO
GO:0019870	potassium channel inhibitor activity	Molecular Function	ISO
GO:0050796	regulation of insulin secretion	Biological Process	ISO