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Gene Information
Gene ID:56338
Full Name:thioredoxin interacting protein
Organism:Mus musculus (Mouse)
Genetic Location:3 47.1 cM
Physical Location:96361879-96365788 on NC_000069.5
Gene Type:protein-coding
Human Ortholog:GeneID: 10628    Symbol (Name): TXNIP (thioredoxin interacting protein)
Ortholog Status:The human GeneID 10628 is also in human dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:AI839138
Fold Change:2.3, 1.7, 2.5, 1.2
Note:4 fold changes are from C57BL/6J trial 1, C57BL/6J trial 2, DBA/2J trial 1, DBA/2J trial 2
Dataset Information
Tissue:Whole brain
Phenotype:Acute ethanol response
Publication:Treadwell et al. Neurochem Res. (2004) Microarray analysis of mouse brain gene expression following acute ethanol treatment. PubMed
Summary:We have analyzed the expression of approximately 24,000 genes using oligonucleotide microarrays to examine the brain expression profiles in two strains of inbred mice, C57BL/6J and DBA/2J, following exposure to an acute dose of ethanol. Our screen identified 61 genes responding to the ethanol treatment beyond a 1.5-fold threshold, with 46 genes altered in both mouse strains and 15 altered in only one strain.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_001009935.2NP_001009935.1NC_000069.5 range: 96361879..96365788
NM_023719.1NP_076208.1NC_000069.5 range: 96361879..96365788
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005737cytoplasmCellular ComponentIDA (10843682)
GO:0004857enzyme inhibitor activityMolecular FunctionIDA (10843682)
GO:0005515protein bindingMolecular FunctionIPI (10843682)
GO:0006350transcriptionBiological ProcessIEA
GO:0006355regulation of transcription, DNA-dependentBiological ProcessIEA
GO:0006979response to oxidative stressBiological ProcessIDA (10843682)
GO:0007049cell cycleBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:56338