| Gene Information |
| Gene ID: | | 56392 |
| Symbol: | | Shoc2 |
| Full Name: | | soc-2 (suppressor of clear) homolog (C. elegans) |
| Alias: | | AU017287|MGC102442|Sur-8|Sur8|mKIAA0862 |
| Organism: | | Mus musculus (Mouse) |
| Chromosome: | | 19 |
| Genetic Location: | | 19 D2 |
| Physical Location: | | 54019369-54107620 on NC_000085.5 |
| Gene Type: | | protein-coding |
| Human Ortholog: | | GeneID: 8036 Symbol (Name): SHOC2 (soc-2 suppressor of clear homolog (C. elegans)) |
| Ortholog Status: | | The human GeneID 8036 is not in current human dataset. |
|
| Gene in Ethanol Study Datasets |
| Gene Information | | Original ID1: | | 104216 (probe) | | Original ID2: | | Shoc2 | | Fold Change: | | 1.35 | | P Value: | | 7.80E-04 | | Note: | | Moderate priority differential expression on U74Av2 array. Direction: D2>B6; Cis LOD:1.1 |
| | Dataset Information | | Name: | | 15597075 | | Method: | | Microarray and QTL | | Tissue: | | Brain | | Phenotype: | | Acute ethanol withdrawal, Chronic ethanol withdrawal, Ethanol preference drinking, Ethanol-stimulated activity | | Publication: | | Hitzemann et al. Alcohol Clin Exp Res. (2004) On the integration of alcohol-related quantitative trait loci and gene expression analyses. PubMed | | Summary: | | Six ethanol-related QTLs, all detected in C57BL/6J and DBA/2J intercrosses were entered into the analysis.Brain gene expression data for the C57BL/6 and DBA/2 strains (n=6 per strain) and an F2 intercross sample (n=56) derived from these strains were obtained by using the Affymetrix U74Av2 and 430A arrays; additional data with the U74Av2 array were available for the extended amygdala, dorsomedial striatum, and hippocampus.Within the 6 QTL intervals, 39 transcripts (430A array) were identified as being highly likely to be differentially expressed between the C57BL/6 and DBA/2 strains at a false discovery rate of 0.01 or better. The p value is from the t test comparison between the C57BL/6J (B6) and DBA/2J (D2) inbred strains. The phenotype of each gene are based on the QTL phenotype. |
|
|
| Gene Refseq Sequence Annotation |
|
| Gene Ontology (GO) Annotation |
| GO ID | GO Term | Category | Evidence (PubMed) | |
| GO:0005515 | protein binding | Molecular Function | IEA | |
|
| Other Database Cross Links |
| NCBI Entrez Gene: | | 56392 |
| MGI: | |
| Ensembl: | | ENSMUSG00000024976 |
| dbSNP: | | Shoc2 |
| AceView: | | Shoc2 |
