ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Clptm1

Full Name:

cleft lip and palate associated transmembrane protein 1

Alias:

N14

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

7 A3

Physical Location:

20216928-20250378 on NC_000073.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 1209 Symbol (Name): CLPTM1 (cleft lip and palate associated transmembrane protein 1)

Ortholog Status:

The human GeneID 1209 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		Clptm1
Original ID2:		D67067

Dataset Information

Name:		15745951
Method:		Microarray
Tissue:		Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:		Acute ethanol response
Publication:		Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:		The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_019649.2	NP_062623.2	NC_000073.5 range: 20216928..20250378, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0009897	external side of plasma membrane	Cellular Component	IDA (7547685)
GO:0016020	membrane	Cellular Component	IEA
GO:0016021	integral to membrane	Cellular Component	RCA (16141072)
GO:0007275	multicellular organismal development	Biological Process	IEA
GO:0030154	cell differentiation	Biological Process	IEA
GO:0033081	regulation of T cell differentiation in the thymus	Biological Process	IMP (9218588)