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Gene Information
Gene ID:5865
Full Name:RAB3B, member RAS oncogene family
Organism:Homo sapiens (Human)
Genetic Location:1p32-p31
Physical Location:52157419-52228935 on NC_000001.9, complement
Gene Type:protein-coding
Orthologs:This gene has Mouse: 69908 ortholog(s) in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:AA235116
Fold Change:1.4, 2.4
Note:Differential Expression on the cDNA array (two fold changes are from two case groups)
Dataset Information
Tissue:Frontal cortex
Phenotype:Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:Lewohl et al. Alcohol Clin Exp Res. (2000) Gene expression in human alcoholism: microarray analysis of frontal cortex. PubMed
Summary:RNA was extracted from postmortem samples of superior frontal cortex of alcoholics and nonalcoholics. Relative levels of RNA were determined by array techniques. This study used both cDNA and oligonucleotide microarrays to provide coverage of a large number of genes and to allow cross-validation for those genes represented on both types of arrays. Expression levels were determined for over 4000 genes and 163 of these were found to differ by 40% or more between alcoholics and nonalcoholics.
Gene Information
Original ID1:RAB3B
Dataset Information
Name:Literature Search
Method:Literature search
Summary:We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_002867.2NP_002858.2NC_000001.9 range: 52157419..52228935, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005886plasma membraneCellular ComponentIEA
GO:0000166nucleotide bindingMolecular FunctionIEA
GO:0003924GTPase activityMolecular FunctionTAS (2501306)
GO:0005525GTP bindingMolecular FunctionIEA
GO:0007264small GTPase mediated signal transductionBiological ProcessIEA
GO:0015031protein transportBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:5865
HuGE Navigator:5865