ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

RAP2A

Full Name:

RAP2A, member of RAS oncogene family

Alias:

K-REV|KREV|RAP2|RbBP-30

Organism:

Homo sapiens (Human)

Chromosome:

13

Genetic Location:

13q34

Physical Location:

96884474-96918244 on NC_000013.9

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		X12534
Fold Change:		-2.53

Dataset Information

Name:		15236863
Method:		Microarray
Tissue:		Prefrontal cortex
Phenotype:		Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:		Iwamoto et al. Neurosci Res. (2004) Decreased expression of NEFH and PCP4/PEP19 in the prefrontal cortex of alcoholics. PubMed
Summary:		We have performed oligonucleotide microarray analysis in postmortem prefrontal cortices of alcoholics. Among about 12,000 genes represented on microarray, a total of 79 genes showed differential expression changes in alcoholics compared with control subjects, consisting of 54 up- and 25 down-regulated genes.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_021033.5	NP_066361.1	NC_000013.9 range: 96884474..96918244

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005622	intracellular	Cellular Component	IEA
GO:0005886	plasma membrane	Cellular Component	IEA
GO:0000166	nucleotide binding	Molecular Function	IEA
GO:0003924	GTPase activity	Molecular Function	TAS (1900290)
GO:0005525	GTP binding	Molecular Function	IEA
GO:0007165	signal transduction	Biological Process	TAS (3045729)
GO:0007264	small GTPase mediated signal transduction	Biological Process	IEA

Other Database Cross Links

NCBI Entrez Gene:

HGNC:

Ensembl:

ENSG00000125249

MIM:

HPRD:

HuGE Navigator:

dbSNP:

GeneCard:

AceView: