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Gene Information
Gene ID:6263
Symbol:RYR3
Full Name:ryanodine receptor 3
Organism:Homo sapiens (Human)
Chromosome:15
Genetic Location:15q14-q15
Physical Location:31390468-31945594 on NC_000015.8
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:AJ001515
Fold Change:2.13
Dataset Information
Name:15236863
Method:Microarray
Tissue:Prefrontal cortex
Phenotype:Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:Iwamoto et al. Neurosci Res. (2004) Decreased expression of NEFH and PCP4/PEP19 in the prefrontal cortex of alcoholics. PubMed
Summary:We have performed oligonucleotide microarray analysis in postmortem prefrontal cortices of alcoholics. Among about 12,000 genes represented on microarray, a total of 79 genes showed differential expression changes in alcoholics compared with control subjects, consisting of 54 up- and 25 down-regulated genes.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_001036.3NP_001027.3NC_000015.8 range: 31390468..31945594
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0016020membraneCellular ComponentIEA
GO:0005887integral to plasma membraneCellular ComponentNR
GO:0005624membrane fractionCellular ComponentNR
GO:0005509calcium ion bindingMolecular FunctionIEA
GO:0005219ryanodine-sensitive calcium-release channel activityMolecular FunctionIEA
GO:0005216ion channel activityMolecular FunctionIEA
GO:0015278calcium-release channel activityMolecular FunctionTAS (9395096)
GO:0004872receptor activityMolecular FunctionIEA
GO:0006811ion transportBiological ProcessIEA
GO:0006816calcium ion transportBiological ProcessTAS (9395096)
GO:0006874cellular calcium ion homeostasisBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:6263
HGNC:10485
Ensembl:
MIM:180903
HPRD:01620
HuGE Navigator:6263
dbSNP:RYR3
GeneCard:RYR3
AceView:RYR3