ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

SDC4

Full Name:

syndecan 4

Alias:

MGC22217|SYND4

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

20q12

Physical Location:

43387341-43410477 on NC_000020.9, complement

Gene Type:

protein-coding

Orthologs:

This gene has Rat: 24771 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Linkage Dataset

Marker

LOD

P value

Location (bp)

D20S119

43082264

Region:		41082264-45082264
Phenotype:		Alcoholism phenotype along with age, gender, and P300 or constraint
Name:		15211641
Method:		Linkage
Publication:		Hill et al. Am J Med Genet B Neuropsychiatr Genet. (2004) A genome wide search for alcoholism susceptibility genes. PubMed
Summary:		A total of 360 markers for 22 autosomes were spaced at an average distance of 9.4cMand genotyping performed for 330 members of these multiplex families. Extensive clinical data, personality variation, and event-related potential characteristics were available for reducing heterogeneity and detecting robust linkage signals. Multipoint linkage analysis using different analytic strategies give strong support for loci on chromosomes 1, 2, 6, 7, 10, 12, 14, 16, and 17. Thirty five markers with LOD score >2.0 at baseline using the binary alcoholism phenotype along with age, gender, and P300 or constraint (Table III). Here we listed the genes between two near markers or genes near a separate marker (within 2Mb).

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_002999.2	NP_002990.2	NC_000020.9 range: 43387341..43410477, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005887	integral to plasma membrane	Cellular Component	NAS (1500433)
GO:0016020	membrane	Cellular Component	IEA
GO:0003674	molecular_function	Molecular Function	ND
GO:0008092	cytoskeletal protein binding	Molecular Function	IEA
GO:0008150	biological_process	Biological Process	ND