| Gene Information |
| Gene ID: | | 64386 |
| Symbol: | | MMP25 |
| Full Name: | | matrix metallopeptidase 25 |
| Alias: | | MMP20|MMP20A|MMPL1|MT-MMP6|MT6-MMP |
| Organism: | | Homo sapiens (Human) |
| Chromosome: | | 16 |
| Genetic Location: | | 16p13.3 |
| Physical Location: | | 3036682-3050727 on NC_000016.8 |
| Gene Type: | | protein-coding |
| Orthologs: | | This gene has no orthologs in other dataset(s). |
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| Gene in Ethanol Study Datasets |
| Gene Information | | Original ID1: | | AJ003147 | | Fold Change: | | 2.45 |
| | Dataset Information | | Name: | | 15236863 | | Method: | | Microarray | | Tissue: | | Prefrontal cortex | | Phenotype: | | Alcohol dependence (AD)/Alcohol abuse/Alcoholism | | Publication: | | Iwamoto et al. Neurosci Res. (2004) Decreased expression of NEFH and PCP4/PEP19 in the prefrontal cortex of alcoholics. PubMed | | Summary: | | We have performed oligonucleotide microarray analysis in postmortem prefrontal cortices of alcoholics. Among about 12,000 genes represented on microarray, a total of 79 genes showed differential expression changes in alcoholics compared with control subjects, consisting of 54 up- and 25 down-regulated genes. |
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| Gene Refseq Sequence Annotation |
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| Gene Ontology (GO) Annotation |
| GO ID | GO Term | Category | Evidence (PubMed) | |
| GO:0031225 | anchored to membrane | Cellular Component | IEA | |
| GO:0009986 | cell surface | Cellular Component | IEP (12493773) | |
| GO:0005576 | extracellular region | Cellular Component | IEA | |
| GO:0005578 | proteinaceous extracellular matrix | Cellular Component | IEA | |
| GO:0005578 | proteinaceous extracellular matrix | Cellular Component | NAS (10628838) | |
| GO:0005886 | plasma membrane | Cellular Component | IEA | |
| GO:0008270 | zinc ion binding | Molecular Function | IEA | |
| GO:0004222 | metalloendopeptidase activity | Molecular Function | IEA | |
| GO:0005509 | calcium ion binding | Molecular Function | IEA | |
| GO:0006508 | proteolysis | Biological Process | NAS (10706098) | |
| GO:0006954 | inflammatory response | Biological Process | NAS (10628838) | |
| GO:0008152 | metabolic process | Biological Process | IEA | |
| GO:0006508 | proteolysis | Biological Process | IEA | |
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| Other Database Cross Links |
| NCBI Entrez Gene: | | 64386 |
| HGNC: | | 14246 |
| Ensembl: | | ENSG00000008516 |
| MIM: | | 608482 |
| HPRD: | | 07090 |
| HuGE Navigator: | | 64386 |
| dbSNP: | | MMP25 |
| GeneCard: | | MMP25 |
| AceView: | | MMP25 |
