ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Asb1

Full Name:

ankyrin repeat and SOCS box-containing protein 1

Alias:

1700029O08Rik|1700054C17Rik|AI426616|AI851378|mKIAA1146

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

1 D|1 57.0 cM

Physical Location:

93437141-93456166 on NC_000067.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 51665 Symbol (Name): ASB1 (ankyrin repeat and SOCS box-containing 1)

Ortholog Status:

The human GeneID 51665 is also in human dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

Asb1

Dataset Information

Name:		16618939
Method:		Microarray
Tissue:		Whole brain
Phenotype:		Alcohol preference
Publication:		Mulligan et al. Proc Natl Acad Sci U S A. (2006) Toward understanding the genetics of alcohol drinking through transcriptome meta-analysis. PubMed
Summary:		Microarray analyses of brain gene expression in three selected lines, and six isogenic strains of mice known to differ markedly in voluntary alcohol consumption provided >4.5 million data points for a meta-analysis. A total of 107 arrays were obtained and arranged into six experimental data sets, allowing the identification of 3,800 unique genes significantly and consistently changed between all models of high or low amounts of alcohol consumption. Here we select the 75 genes with the largest effect size (\|d\|) and lowest Q values.

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Ap1q	Alcohol Preference Drinking	1	76	45-95 (cM)	4.5		Significant	PARC

Gene Refseq Sequence Annotation

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005575	cellular_component	Cellular Component	ND
GO:0006512	ubiquitin cycle	Biological Process	IEA
GO:0007242	intracellular signaling cascade	Biological Process	IEA
GO:0007275	multicellular organismal development	Biological Process	IEA
GO:0030539	male genitalia development	Biological Process	IMP (11509662)