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Gene Information
Gene ID:654309
Symbol:Nrp
Organism:Mus musculus (Mouse)
Chromosome:12
Genetic Location:12 D2
Physical Location:88784460-88784966 on NC_000078.5, complement
Gene Type:protein-coding
Human Ortholog:This gene has no human ortholog.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Nrp
Original ID2:D50086
Dataset Information
Name:15745951
Method:Microarray
Tissue:Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:Acute ethanol response
Publication:Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_001013372.2NP_001013390.1NC_000078.5 range: 88784460..88784966, complement
Other Database Cross Links
NCBI Entrez Gene:654309
MGI:
Ensembl:ENSMUSG00000021041
dbSNP:Nrp
AceView:Nrp