ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

SLC25A1

Full Name:

solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1

Alias:

CTP|SLC20A3

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

22q11.21

Physical Location:

17543094-17546284 on NC_000022.9, complement

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		L77567
Fold Change:		3.02

Dataset Information

Name:		15236863
Method:		Microarray
Tissue:		Prefrontal cortex
Phenotype:		Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:		Iwamoto et al. Neurosci Res. (2004) Decreased expression of NEFH and PCP4/PEP19 in the prefrontal cortex of alcoholics. PubMed
Summary:		We have performed oligonucleotide microarray analysis in postmortem prefrontal cortices of alcoholics. Among about 12,000 genes represented on microarray, a total of 79 genes showed differential expression changes in alcoholics compared with control subjects, consisting of 54 up- and 25 down-regulated genes.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_005984.1	NP_005975.1	NC_000022.9 range: 17543094..17546284, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005739	mitochondrion	Cellular Component	IEA
GO:0005743	mitochondrial inner membrane	Cellular Component	TAS
GO:0016020	membrane	Cellular Component	IEA
GO:0016021	integral to membrane	Cellular Component	IEA
GO:0005215	transporter activity	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IPI (17353931)
GO:0015137	citrate transmembrane transporter activity	Molecular Function	TAS (8666394)
GO:0006810	transport	Biological Process	IEA
GO:0006843	mitochondrial citrate transport	Biological Process	TAS