Logo
Home Search BLAST Integration Document Link Support Citation

Gene Information
Gene ID:66141
Symbol:Ifitm3
Full Name:interferon induced transmembrane protein 3
Alias:1110004C05Rik|Cd225|Cdw217|Fgls|IP15|mil-1
Organism:Mus musculus (Mouse)
Chromosome:7
Genetic Location:7 F5
Physical Location:148195488-148196642 on NC_000073.5, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 10410    Symbol (Name): IFITM3 (interferon induced transmembrane protein 3 (1-8U))
Ortholog Status:The human GeneID 10410 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Ifitm3
Original ID2:AW125390
Dataset Information
Name:15745951
Method:Microarray
Tissue:Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:Acute ethanol response
Publication:Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_025378.2NP_079654.1NC_000073.5 range: 148195488..148196642, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0016021integral to membraneCellular ComponentRCA (16141072)
GO:0016023cytoplasmic membrane-bounded vesicleCellular ComponentIDA (15184081)
GO:0008285negative regulation of cell proliferationBiological ProcessIDA (15184081)
GO:0009607response to biotic stimulusBiological ProcessRCA (16141072)
Other Database Cross Links
NCBI Entrez Gene:66141
MGI:
Ensembl:ENSMUSG00000025492
dbSNP:Ifitm3
AceView:Ifitm3