ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Ifitm3

Full Name:

interferon induced transmembrane protein 3

Alias:

1110004C05Rik|Cd225|Cdw217|Fgls|IP15|mil-1

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

7 F5

Physical Location:

148195488-148196642 on NC_000073.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 10410 Symbol (Name): IFITM3 (interferon induced transmembrane protein 3 (1-8U))

Ortholog Status:

The human GeneID 10410 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		Ifitm3
Original ID2:		AW125390

Dataset Information

Name:		15745951
Method:		Microarray
Tissue:		Nucleus accumbens, prefrontal cortex, and ventral tegmental area
Phenotype:		Acute ethanol response
Publication:		Kerns et al. J Neurosci. (2005) Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. PubMed
Summary:		The inbred mouse strains DBA/2J and C57BL/6J exhibit contrasting acute behavioral responses to ethanol. We used oligonucleotide microarrays and bioinformatics methods to characterize patterns of gene expression in three brain regions of the mesolimbic reward pathway of these strains. Expression profiling included examination of both differences in gene expression 4 h after acute ethanol (2 g/kg). Using a rigorous stepwise method for microarray analysis, we identified 307 ethanol-regulated genes in the nucleus accumbens, prefrontal cortex, and ventral tegmental area.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_025378.2	NP_079654.1	NC_000073.5 range: 148195488..148196642, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0016021	integral to membrane	Cellular Component	RCA (16141072)
GO:0016023	cytoplasmic membrane-bounded vesicle	Cellular Component	IDA (15184081)
GO:0008285	negative regulation of cell proliferation	Biological Process	IDA (15184081)
GO:0009607	response to biotic stimulus	Biological Process	RCA (16141072)