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Gene Information
Gene ID:6774
Full Name:signal transducer and activator of transcription 3 (acute-phase response factor)
Organism:Homo sapiens (Human)
Genetic Location:17q21.31
Physical Location:37718868-37794038 on NC_000017.9, complement
Gene Type:protein-coding
Orthologs:This gene has Rat: 25125 ortholog(s) in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:STAT3
Dataset Information
Name:Literature Search
Method:Literature search
Summary:We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_003150.3NP_003141.2NC_000017.9 range: 37718868..37794038, complement
NM_139276.2NP_644805.1NC_000017.9 range: 37718868..37794038, complement
NM_213662.1NP_998827.1NC_000017.9 range: 37718868..37794038, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005737cytoplasmCellular ComponentTAS (7512451)
GO:0005634nucleusCellular ComponentIEA
GO:0005634nucleusCellular ComponentIDA (12444102)
GO:0008134transcription factor bindingMolecular FunctionIPI (15664994)
GO:0005515protein bindingMolecular FunctionIEA
GO:0005509calcium ion bindingMolecular FunctionIEA
GO:0005062hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activityMolecular FunctionTAS (7512451)
GO:0004871signal transducer activityMolecular FunctionIEA
GO:0003700transcription factor activityMolecular FunctionTAS (7512451|8675499)
GO:0003700transcription factor activityMolecular FunctionIEA
GO:0007399nervous system developmentBiological ProcessTAS (10205054)
GO:0007259JAK-STAT cascadeBiological ProcessTAS (15664994)
GO:0007165signal transductionBiological ProcessTAS (7512451|10205054)
GO:0007165signal transductionBiological ProcessIEA
GO:0006953acute-phase responseBiological ProcessNR
GO:0006928cell motilityBiological ProcessTAS (9670957)
GO:0006355regulation of transcription, DNA-dependentBiological ProcessIEA
GO:0000122negative regulation of transcription from RNA polymerase II promoterBiological ProcessTAS (8675499)
GO:0019221cytokine and chemokine mediated signaling pathwayBiological ProcessNAS (15664994)
Other Database Cross Links
NCBI Entrez Gene:6774
HuGE Navigator:6774