ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

STAT3

Full Name:

signal transducer and activator of transcription 3 (acute-phase response factor)

Alias:

APRF|FLJ20882|MGC16063

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

17q21.31

Physical Location:

37718868-37794038 on NC_000017.9, complement

Gene Type:

protein-coding

Orthologs:

This gene has Rat: 25125 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

STAT3

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005737	cytoplasm	Cellular Component	TAS (7512451)
GO:0005634	nucleus	Cellular Component	IEA
GO:0005634	nucleus	Cellular Component	IDA (12444102)
GO:0008134	transcription factor binding	Molecular Function	IPI (15664994)
GO:0005515	protein binding	Molecular Function	IEA
GO:0005509	calcium ion binding	Molecular Function	IEA
GO:0005062	hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity	Molecular Function	TAS (7512451)
GO:0004871	signal transducer activity	Molecular Function	IEA
GO:0003700	transcription factor activity	Molecular Function	TAS (7512451\|8675499)
GO:0003700	transcription factor activity	Molecular Function	IEA
GO:0007399	nervous system development	Biological Process	TAS (10205054)
GO:0007259	JAK-STAT cascade	Biological Process	TAS (15664994)
GO:0007165	signal transduction	Biological Process	TAS (7512451\|10205054)
GO:0007165	signal transduction	Biological Process	IEA
GO:0006953	acute-phase response	Biological Process	NR
GO:0006928	cell motility	Biological Process	TAS (9670957)
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IEA
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	Biological Process	TAS (8675499)
GO:0019221	cytokine and chemokine mediated signaling pathway	Biological Process	NAS (15664994)