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Gene Information
Gene ID:67760
Full Name:solute carrier family 38, member 2
Organism:Mus musculus (Mouse)
Genetic Location:15 F1
Physical Location:96517822-96530128 on NC_000081.5, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 54407    Symbol (Name): SLC38A2 (solute carrier family 38, member 2)
Ortholog Status:The human GeneID 54407 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:AA245554
Fold Change:5.8, 3.2
Note:ISS preferentially expressed gene. Two ratios of ISS/ILS are from cDNA array and RT-PCR.
Dataset Information
Tissue:Whole brain
Phenotype:Ethanol sensitivity
Publication:Xu et al. Alcohol Clin Exp Res. (2001) Comparison of global brain gene expression profiles between inbred long-sleep and inbred short-sleep mice by high-density gene array hybridization. PubMed
Summary:Inbred long-sleep (ILS) and short-sleep (ISS) mice show significant central nervous system-mediated differences in sleep time for sedative dose of ethanol and are frequently used as a rodent model for ethanol sensitivity. In this study, we used both the gene discovery array (GDA) and the Mouse GEM 1 Microarray. Complex probes were prepared from total brain mRNA of ILS or ISS mice by using reverse transcription and 33P labeling. Differentially expressed genes identified from each method were confirmed by relative quantitative reverse transcription-polymerase chain reaction (RT-PCR). A total of 41 genes or expressed sequence tags (ESTs) display significant expression level differences between brains of ILS and ISS mice after GDA, GEM1 hybridization, and quantitative RTPCR confirmation. Among them, 18 clones were expressed higher in ILS mice, and 23 clones were expressed higher in ISS mice.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_175121.3NP_780330.2NC_000081.5 range: 96517822..96530128, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005886plasma membraneCellular ComponentIDA (17003038)
GO:0016021integral to membraneCellular ComponentIEA
GO:0016020membraneCellular ComponentIEA
GO:0015293symporter activityMolecular FunctionIEA
GO:0015171amino acid transmembrane transporter activityMolecular FunctionIDA (17003038)
GO:0031402sodium ion bindingMolecular FunctionIEA
GO:0006865amino acid transportBiological ProcessIDA (17003038)
GO:0006814sodium ion transportBiological ProcessIEA
GO:0006811ion transportBiological ProcessIEA
GO:0006810transportBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:67760