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Gene Information
Gene ID:6785
Symbol:ELOVL4
Full Name:elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4
Alias:ADMD|FLJ17667|FLJ92876|STGD2|STGD3
Organism:Homo sapiens (Human)
Chromosome:6
Genetic Location:6q14
Physical Location:80681247-80713940 on NC_000006.10, complement
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Hs.101915
Note:"Class II, down-regulated gene"
Dataset Information
Name:16292326
Method:Microarray
Tissue:Frontal cortex
Phenotype:Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:Liu et al. Neuropsychopharmacology. (2006) Patterns of gene expression in the frontal cortex discriminate alcoholic from nonalcoholic individuals. PubMed
Summary:In the present study, microarray analysis (approximately 47,000 elements) was performed on the superior frontal cortex of 27 individual human cases (14 well characterized alcoholics and 13 matched controls). A classification system was developed in which differentially expressed genes were divided into two classes. Class I genes were qualitatively different, that is, they were predominantly detected in one group but not the other. Multiple criteria were used to define Class II genes. First, only the genes detected on over 80% of the arrays in both groups. Class II were then defined as those consistently detected in both groups having absolute PLS loadings scores of >2.0 and t- probabilities of <0.05.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_022726.3NP_073563.1NC_000006.10 range: 80681247..80713940, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005575cellular_componentCellular ComponentND
GO:0005783endoplasmic reticulumCellular ComponentIEA
GO:0005789endoplasmic reticulum membraneCellular ComponentIEA
GO:0016020membraneCellular ComponentIEA
GO:0016021integral to membraneCellular ComponentIEA
GO:0008020G-protein coupled photoreceptor activityMolecular FunctionNAS (11138005)
GO:0006633fatty acid biosynthetic processBiological ProcessNAS (11138005)
GO:0007601visual perceptionBiological ProcessIEA
GO:0050896response to stimulusBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:6785
HGNC:14415
Ensembl:ENSG00000118402
MIM:605512
HPRD:05697
HuGE Navigator:6785
dbSNP:ELOVL4
GeneCard:ELOVL4
AceView:ELOVL4