Logo
Home Search BLAST Integration Document Link Support Citation

Gene Information
Gene ID:6845
Symbol:VAMP7
Full Name:vesicle-associated membrane protein 7
Alias:SYBL1|TI-VAMP|VAMP-7
Organism:Homo sapiens (Human)
Chromosome:X|Y
Genetic Location:Xq28 and Yq12
Physical Location:154764206-154826613 on NC_000023.9
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Hs.24167
Note:"Class II, down-regulated gene"
Dataset Information
Name:16292326
Method:Microarray
Tissue:Frontal cortex
Phenotype:Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:Liu et al. Neuropsychopharmacology. (2006) Patterns of gene expression in the frontal cortex discriminate alcoholic from nonalcoholic individuals. PubMed
Summary:In the present study, microarray analysis (approximately 47,000 elements) was performed on the superior frontal cortex of 27 individual human cases (14 well characterized alcoholics and 13 matched controls). A classification system was developed in which differentially expressed genes were divided into two classes. Class I genes were qualitatively different, that is, they were predominantly detected in one group but not the other. Multiple criteria were used to define Class II genes. First, only the genes detected on over 80% of the arrays in both groups. Class II were then defined as those consistently detected in both groups having absolute PLS loadings scores of >2.0 and t- probabilities of <0.05.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_005638.3NP_005629.1NC_000023.9 range: 154764206..154826613
NM_005638.3NP_005629.1NC_000024.8 range: 57623406..57685813
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0045335phagocytic vesicleCellular ComponentISS (15470500)
GO:0016021integral to membraneCellular ComponentIEA
GO:0031201SNARE complexCellular ComponentISS (15133481)
GO:0031410cytoplasmic vesicleCellular ComponentIEA
GO:0031902late endosome membraneCellular ComponentISS (10459012)
GO:0005794Golgi apparatusCellular ComponentIEA
GO:0005789endoplasmic reticulum membraneCellular ComponentISS (16495485)
GO:0005783endoplasmic reticulumCellular ComponentIEA
GO:0005768endosomeCellular ComponentIEA
GO:0005765lysosomal membraneCellular ComponentISS (10459012)
GO:0016020membraneCellular ComponentIEA
GO:0005515protein bindingMolecular FunctionISS (14993220)
GO:0008333endosome to lysosome transportBiological ProcessIDA (10888671)
GO:0017156calcium ion-dependent exocytosisBiological ProcessISS (14993220)
GO:0006911phagocytosis, engulfmentBiological ProcessISS (15133481)
GO:0006906vesicle fusionBiological ProcessIDA (10888671)
GO:0006888ER to Golgi vesicle-mediated transportBiological ProcessISS (6495485)
GO:0043308eosinophil degranulationBiological ProcessISS (14993220)
GO:0043312neutrophil degranulationBiological ProcessISS (14993220)
GO:0015031protein transportBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:6845
HGNC:11486
Ensembl:ENSG00000124333
MIM:300053
HPRD:02084
HuGE Navigator:6845
dbSNP:VAMP7
GeneCard:VAMP7
AceView:VAMP7