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Gene Information
Gene ID:685879
Full Name:JAZF zinc finger 1
Organism:Rattus norvegicus (Rat)
Genetic Location:4q24
Physical Location:81086246-81403736 on NC_005103.2, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 221895    Symbol (Name): JAZF1 (JAZF zinc finger 1)
Ortholog Status:The human GeneID 221895 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:LOC685879
Fold Change:1.64
P Value:0
Gene Information
Original ID1:LOC685879
Fold Change:1.71
P Value:0
Tissue:Frontal cortex
Gene Information
Original ID1:LOC685879
Fold Change:1.43
P Value:0
Gene Information
Original ID1:LOC685879
Fold Change:1.8
P Value:0
Tissue:Nucleus accumbens
Gene Information
Original ID1:LOC685879
Fold Change:1.76
P Value:0
Dataset Information
Method:Microarray and QTL
Tissue:Nucleus accumbens, frontal cortex, amygdala, hippocampus, and striatum
Phenotype:Alcohol Preference, alcohol-preferring, alcohol-nonpreferring
Publication:Carr et al. Alcohol Clin Exp Res. (2007) Identification of candidate genes for alcohol preference by expression profiling of congenic rat strains. PubMed
Summary:A highly significant quantitative trait locus (QTL) on chromosome 4 that influenced alcohol preference was identified by analyzing crosses between the iP (inbred alcohol-preferring) and iNP (inbred alcohol-nonpreferring) rats. Congenic strains in which the iP chromosome 4 QTL interval was transferred to the iNP (NP.P) exhibited the expected increase in alcohol consumption compared with the iNP background strain. Analyses within individual brain regions that focused on genes within the QTL interval detected differential expression in all 5 brain regions; a total of 35 genes were detected in at least 1 region, ranging from 6 genes in the nucleus accumbens to 22 in the frontal cortex.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
XM_001065610.1XP_001065610.1NC_005103.2 range: 81086246..81403736, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0017053transcriptional repressor complexCellular ComponentISS
GO:0003714transcription corepressor activityMolecular FunctionISS
GO:0000122negative regulation of transcription from RNA polymerase II promoterBiological ProcessISS
Other Database Cross Links
NCBI Entrez Gene:685879