ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

TFR2

Full Name:

transferrin receptor 2

Alias:

HFE3|MGC126368|TFRC2

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

7q22

Physical Location:

100055974-100077108 on NC_000007.12, complement

Gene Type:

protein-coding

Orthologs:

This gene has Mouse: 50765 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

TFR2

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_003227.3	NP_003218.2	NC_000007.12 range: 100055974..100077108, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005737	cytoplasm	Cellular Component	IEA
GO:0005886	plasma membrane	Cellular Component	IEA
GO:0005887	integral to plasma membrane	Cellular Component	NAS (10409623)
GO:0004872	receptor activity	Molecular Function	IEA
GO:0004998	transferrin receptor activity	Molecular Function	NAS (10409623)
GO:0008233	peptidase activity	Molecular Function	IEA
GO:0006508	proteolysis	Biological Process	IEA
GO:0006826	iron ion transport	Biological Process	NAS (10409623)
GO:0006879	cellular iron ion homeostasis	Biological Process	TAS (15319276)