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Gene Information
Gene ID:7043
Symbol:TGFB3
Full Name:transforming growth factor, beta 3
Alias:ARVD|FLJ16571|TGF-beta3
Organism:Homo sapiens (Human)
Chromosome:14
Genetic Location:14q24
Physical Location:75494194-75517241 on NC_000014.7, complement
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:X14885
Fold Change:2.32
Dataset Information
Name:15236863
Method:Microarray
Tissue:Prefrontal cortex
Phenotype:Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:Iwamoto et al. Neurosci Res. (2004) Decreased expression of NEFH and PCP4/PEP19 in the prefrontal cortex of alcoholics. PubMed
Summary:We have performed oligonucleotide microarray analysis in postmortem prefrontal cortices of alcoholics. Among about 12,000 genes represented on microarray, a total of 79 genes showed differential expression changes in alcoholics compared with control subjects, consisting of 54 up- and 25 down-regulated genes.
Gene Information
Original ID1:TGFB3
Dataset Information
Name:Literature Search
Method:Literature search
Summary:We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_003239.2NP_003230.1NC_000014.7 range: 75494194..75517241, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0031093platelet alpha granule lumenCellular ComponentEXP (3457014)
GO:0005576extracellular regionCellular ComponentEXP (3457014)
GO:0005576extracellular regionCellular ComponentIEA
GO:0005160transforming growth factor beta receptor bindingMolecular FunctionTAS (7493022)
GO:0005515protein bindingMolecular FunctionIPI (11850637)
GO:0008083growth factor activityMolecular FunctionIEA
GO:0016049cell growthBiological ProcessIEA
GO:0009887organ morphogenesisBiological ProcessTAS (7493022)
GO:0008283cell proliferationBiological ProcessIEA
GO:0007267cell-cell signalingBiological ProcessTAS (3164476)
GO:0007165signal transductionBiological ProcessTAS (3164476)
GO:0001837epithelial to mesenchymal transitionBiological ProcessTAS (14679171)
Other Database Cross Links
NCBI Entrez Gene:7043
HGNC:11769
Ensembl:ENSG00000119699
MIM:190230
HPRD:01829
HuGE Navigator:7043
dbSNP:TGFB3
GeneCard:TGFB3
AceView:TGFB3