ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

TIE1

Full Name:

tyrosine kinase with immunoglobulin-like and EGF-like domains 1

Alias:

JTK14|TIE

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

1p34-p33

Physical Location:

43539250-43561365 on NC_000001.9

Gene Type:

protein-coding

Orthologs:

This gene has Mouse: 21846 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

TIE1

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_005424.2	NP_005415.1	NC_000001.9 range: 43539250..43561365

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005887	integral to plasma membrane	Cellular Component	TAS (1312667)
GO:0016020	membrane	Cellular Component	IEA
GO:0000166	nucleotide binding	Molecular Function	IEA
GO:0005524	ATP binding	Molecular Function	IEA
GO:0004872	receptor activity	Molecular Function	IEA
GO:0004714	transmembrane receptor protein tyrosine kinase activity	Molecular Function	TAS (1312667)
GO:0004713	protein-tyrosine kinase activity	Molecular Function	IEA
GO:0016740	transferase activity	Molecular Function	IEA
GO:0006468	protein amino acid phosphorylation	Biological Process	IEA
GO:0007165	signal transduction	Biological Process	TAS (1312667)
GO:0007498	mesoderm development	Biological Process	TAS (7596437)