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Gene Information
Gene ID:7414
Symbol:VCL
Full Name:vinculin
Alias:CMD1W|MVCL
Organism:Homo sapiens (Human)
Chromosome:10
Genetic Location:10q22.1-q23
Physical Location:75427877-75549923 on NC_000010.9
Gene Type:protein-coding
Orthologs:This gene has Fly: 31201 ortholog(s) in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:VCL
Dataset Information
Name:Literature Search
Method:Literature search
Summary:We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_003373.3NP_003364.1NC_000010.9 range: 75427877..75549923
NM_014000.2NP_054706.1NC_000010.9 range: 75427877..75549923
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0015629actin cytoskeletonCellular ComponentIEA
GO:0043234protein complexCellular ComponentIDA (9700171)
GO:0005737cytoplasmCellular ComponentIEA
GO:0005911intercellular junctionCellular ComponentISS
GO:0005912adherens junctionCellular ComponentISS
GO:0005925focal adhesionCellular ComponentISS
GO:0043034costamereCellular ComponentISS
GO:0030055cell-substrate junctionCellular ComponentNAS (2116004)
GO:0016491oxidoreductase activityMolecular FunctionISS
GO:0003779actin bindingMolecular FunctionIDA (7816144)
GO:0005198structural molecule activityMolecular FunctionIEA
GO:0045294alpha-catenin bindingMolecular FunctionIPI (9700171)
GO:0030032lamellipodium biogenesisBiological ProcessISS
GO:0007155cell adhesionBiological ProcessTAS (15501673)
GO:0030336negative regulation of cell migrationBiological ProcessTAS (15494027)
GO:0006928cell motilityBiological ProcessTAS (16130169)
GO:0043297apical junction assemblyBiological ProcessIMP (9700171)
Other Database Cross Links
NCBI Entrez Gene:7414
HGNC:12665
Ensembl:ENSG00000035403
MIM:193065
HPRD:01900
HuGE Navigator:7414
dbSNP:VCL
GeneCard:VCL
AceView:VCL