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Gene Information
Gene ID:745
Symbol:C11orf9
Full Name:chromosome 11 open reading frame 9
Alias:KIAA0954|MGC10781
Organism:Homo sapiens (Human)
Chromosome:11
Genetic Location:11q12-q13.1
Physical Location:61279436-61312564 on NC_000011.8
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Hs.473109
Note:"Class II, down-regulated gene"
Dataset Information
Name:16292326
Method:Microarray
Tissue:Frontal cortex
Phenotype:Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:Liu et al. Neuropsychopharmacology. (2006) Patterns of gene expression in the frontal cortex discriminate alcoholic from nonalcoholic individuals. PubMed
Summary:In the present study, microarray analysis (approximately 47,000 elements) was performed on the superior frontal cortex of 27 individual human cases (14 well characterized alcoholics and 13 matched controls). A classification system was developed in which differentially expressed genes were divided into two classes. Class I genes were qualitatively different, that is, they were predominantly detected in one group but not the other. Multiple criteria were used to define Class II genes. First, only the genes detected on over 80% of the arrays in both groups. Class II were then defined as those consistently detected in both groups having absolute PLS loadings scores of >2.0 and t- probabilities of <0.05.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_013279.1NP_037411.1NC_000011.8 range: 61279436..61312564
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005634nucleusCellular ComponentIEA
GO:0016020membraneCellular ComponentIEA
GO:0016021integral to membraneCellular ComponentIEA
GO:0003700transcription factor activityMolecular FunctionIEA
GO:0045449regulation of transcriptionBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:745
HGNC:1181
Ensembl:ENSG00000124920
MIM:608329
HPRD:12213
HuGE Navigator:745
dbSNP:C11orf9
GeneCard:C11orf9
AceView:C11orf9