ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

CA2

Full Name:

carbonic anhydrase II

Alias:

CA-II|CAII|Car2

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

8q22

Physical Location:

86563382-86580972 on NC_000008.9

Gene Type:

protein-coding

Orthologs:

This gene has Mouse: 12349 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

CA2

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Information

Gene Information

Dataset Information

Name:		15816859
Method:		Microarray
Tissue:		Prefrontal cortex and nucleus accumbens
Phenotype:		Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:		Flatscher-Bader et al. J Neurochem.(2005) Alcohol-responsive genes in the frontal cortex and nucleus accumbens of human alcoholics. PubMed
Summary:		Genes with a mean fold change > 1.5 or < 0.7 were selected and annotated. Values are taken from microarray analysis and represent mean ratios of alcoholic cases compared with matched control cases(n = 6). P values were from t-test.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_000067.2	NP_000058.1	NC_000008.9 range: 86563382..86580972

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005737	cytoplasm	Cellular Component	IDA (114507)
GO:0004089	carbonate dehydratase activity	Molecular Function	TAS (1928091)
GO:0008270	zinc ion binding	Molecular Function	IDA (3151020)
GO:0016829	lyase activity	Molecular Function	IEA
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0006730	one-carbon compound metabolic process	Biological Process	IEA