ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

CACNA1A

Full Name:

calcium channel, voltage-dependent, P/Q type, alpha 1A subunit

Alias:

APCA|CACNL1A4|CAV2.1|EA2|FHM|HPCA|MHP|MHP1|SCA6

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

19p13.2-p13.1

Physical Location:

13178255-13478273 on NC_000019.8, complement

Gene Type:

protein-coding

Orthologs:

This gene has Mouse: 12286 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

CACNA1A

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0042995	cell projection	Cellular Component	IDA (16595610)
GO:0016021	integral to membrane	Cellular Component	TAS (16595610)
GO:0016021	integral to membrane	Cellular Component	IEA
GO:0016020	membrane	Cellular Component	IEA
GO:0005891	voltage-gated calcium channel complex	Cellular Component	IEA
GO:0005886	plasma membrane	Cellular Component	IDA (16595610)
GO:0005886	plasma membrane	Cellular Component	EXP (8825650)
GO:0005737	cytoplasm	Cellular Component	IDA (16595610)
GO:0005634	nucleus	Cellular Component	IDA (16595610)
GO:0019905	syntaxin binding	Molecular Function	IDA (8692999)
GO:0005244	voltage-gated ion channel activity	Molecular Function	IEA
GO:0005245	voltage-gated calcium channel activity	Molecular Function	IDA (12451115)
GO:0005245	voltage-gated calcium channel activity	Molecular Function	IEA
GO:0005216	ion channel activity	Molecular Function	IEA
GO:0005245	voltage-gated calcium channel activity	Molecular Function	ISS
GO:0005509	calcium ion binding	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IPI (8692999\|11865310)
GO:0006816	calcium ion transport	Biological Process	IEA
GO:0008219	cell death	Biological Process	IDA (16595610)
GO:0006811	ion transport	Biological Process	IEA
GO:0007204	elevation of cytosolic calcium ion concentration	Biological Process	ISS