ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

77579

Symbol:

Myh10

Full Name:

myosin, heavy polypeptide 10, non-muscle

Alias:

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

11 B3|11 40.0 cM

Physical Location:

68505416-68630125 on NC_000077.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 4628 Symbol (Name): MYH10 (myosin, heavy chain 10, non-muscle)

Ortholog Status:

The human GeneID 4628 is also in human dataset(s).

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Lore4	Alcohol-induced Loss of Righting Reflex	11		36-42 (cM)	6.5		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_175260.2	NP_780469.1	NC_000077.5 range: 68505416..68630125

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0001725	stress fiber	Cellular Component	IMP (14617807)
GO:0005819	spindle	Cellular Component	IDA (9725909)
GO:0005737	cytoplasm	Cellular Component	IDA (8482409\|9725909\|12724421\|12893741\|15177565\|16895968)
GO:0005938	cell cortex	Cellular Component	IDA (8482409\|9725909)
GO:0016459	myosin complex	Cellular Component	IDA (8482409\|9356462\|9725909)
GO:0030424	axon	Cellular Component	IDA (15880105)
GO:0030426	growth cone	Cellular Component	IDA (15880105)
GO:0005886	plasma membrane	Cellular Component	IDA (16895968)
GO:0031594	neuromuscular junction	Cellular Component	IDA (16012337)
GO:0001725	stress fiber	Cellular Component	ISO
GO:0043197	dendritic spine	Cellular Component	IDA (16481398)
GO:0001725	stress fiber	Cellular Component	IDA (12893741\|14699073)
GO:0043005	neuron projection	Cellular Component	IDA (16481398)
GO:0043025	cell soma	Cellular Component	IDA (16481398)
GO:0000146	microfilament motor activity	Molecular Function	ISO
GO:0043531	ADP binding	Molecular Function	ISO
GO:0051015	actin filament binding	Molecular Function	ISO
GO:0030898	actin-dependent ATPase activity	Molecular Function	ISO
GO:0005524	ATP binding	Molecular Function	ISO
GO:0003779	actin binding	Molecular Function	IEA
GO:0003774	motor activity	Molecular Function	IEA
GO:0000166	nucleotide binding	Molecular Function	IEA
GO:0005516	calmodulin binding	Molecular Function	RCA (12466851)
GO:0005515	protein binding	Molecular Function	IPI (12724421\|15663482)
GO:0001778	plasma membrane repair	Biological Process	IMP (14617807)
GO:0031175	neurite development	Biological Process	IMP (15880105)
GO:0001764	neuron migration	Biological Process	IMP (10712438\|11283949\|15034141\|16481398)
GO:0001701	in utero embryonic development	Biological Process	IMP (9356462\|11283949\|12893741)
GO:0000281	cytokinesis after mitosis	Biological Process	ISO
GO:0007512	adult heart development	Biological Process	IMP (9356462\|10712438\|12893741)
GO:0000281	cytokinesis after mitosis	Biological Process	IMP (12893741)
GO:0050885	neuromuscular process controlling balance	Biological Process	IMP (16481398)
GO:0055003	cardiac myofibril assembly	Biological Process	IMP (9356462)
GO:0055015	ventricular cardiac muscle cell development	Biological Process	IMP (12893741)
GO:0030239	myofibril assembly	Biological Process	IMP (10712438)
GO:0030048	actin filament-based movement	Biological Process	ISO
GO:0006887	exocytosis	Biological Process	IMP (14617807)
GO:0006930	substrate-bound cell migration, cell extension	Biological Process	IMP (14699073)
GO:0007097	nuclear migration	Biological Process	IMP (16895968)
GO:0007409	axonogenesis	Biological Process	IMP (11283949)
GO:0007411	axon guidance	Biological Process	IMP (15880105)
GO:0007420	brain development	Biological Process	IMP (16481398)
GO:0008283	cell proliferation	Biological Process	IMP (12893741)
GO:0008360	regulation of cell shape	Biological Process	IMP (16895968)
GO:0021592	fourth ventricle development	Biological Process	IMP (11283949\|16481398)
GO:0021670	lateral ventricle development	Biological Process	IMP (9356462\|10712438\|11283949)
GO:0021678	third ventricle development	Biological Process	IMP (11283949)
GO:0021680	cerebellar Purkinje cell layer development	Biological Process	IMP (16481398)
GO:0030036	actin cytoskeleton organization and biogenesis	Biological Process	IGI (16249236)
GO:0060041	retina development in camera-type eye	Biological Process	IMP (9356462\|11283949)