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Gene Information
Gene ID:7915
Symbol:ALDH5A1
Full Name:aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase)
Alias:SSADH|SSDH
Organism:Homo sapiens (Human)
Chromosome:6
Genetic Location:6p22.2-p22.3
Physical Location:24603175-24645413 on NC_000006.10
Gene Type:protein-coding
Orthologs:This gene has Rat: 291133 ortholog(s) in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:ALDH5A1
Dataset Information
Name:Literature Search
Method:Literature search
Summary:We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_001080.3NP_001071.1NC_000006.10 range: 24603175..24645413
NM_170740.1NP_733936.1NC_000006.10 range: 24603175..24645413
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005625soluble fractionCellular ComponentIDA (16199352)
GO:0005739mitochondrionCellular ComponentISS
GO:0004777succinate-semialdehyde dehydrogenase activityMolecular FunctionIDA (9683595)
GO:0016491oxidoreductase activityMolecular FunctionIEA
GO:0042803protein homodimerization activityMolecular FunctionIC (16199352)
GO:0004777succinate-semialdehyde dehydrogenase activityMolecular FunctionISS (7814412)
GO:0004777succinate-semialdehyde dehydrogenase activityMolecular FunctionIEA
GO:0046459short-chain fatty acid metabolic processBiological ProcessISS
GO:0042135neurotransmitter catabolic processBiological ProcessISS
GO:0022904respiratory electron transport chainBiological ProcessISS
GO:0009450gamma-aminobutyric acid catabolic processBiological ProcessIMP (15037717)
GO:0009450gamma-aminobutyric acid catabolic processBiological ProcessIDA (9683595)
GO:0008152metabolic processBiological ProcessIEA
GO:0007417central nervous system developmentBiological ProcessIMP (9683595)
GO:0006749glutathione metabolic processBiological ProcessISS
GO:0006681galactosylceramide metabolic processBiological ProcessISS
GO:0006650glycerophospholipid metabolic processBiological ProcessISS
GO:0006541glutamine metabolic processBiological ProcessISS
GO:0006536glutamate metabolic processBiological ProcessISS
GO:0006105succinate metabolic processBiological ProcessISS
GO:0006083acetate metabolic processBiological ProcessISS
GO:0006006glucose metabolic processBiological ProcessISS
GO:0051289protein homotetramerizationBiological ProcessIDA (16199352)
Other Database Cross Links
NCBI Entrez Gene:7915
HGNC:408
Ensembl:ENSG00000112294
MIM:610045
HPRD:08361
HuGE Navigator:7915
dbSNP:ALDH5A1
GeneCard:ALDH5A1
AceView:ALDH5A1