ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

HIST2H2BE

Full Name:

histone cluster 2, H2be

Alias:

GL105|H2B|H2B.1|H2B/q|H2BFQ|MGC119802|MGC119804|MGC129733|MGC129734

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

1q21-q23

Physical Location:

148122633-148124855 on NC_000001.9, complement

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		X57985
Fold Change:		2.03

Dataset Information

Name:		15236863
Method:		Microarray
Tissue:		Prefrontal cortex
Phenotype:		Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:		Iwamoto et al. Neurosci Res. (2004) Decreased expression of NEFH and PCP4/PEP19 in the prefrontal cortex of alcoholics. PubMed
Summary:		We have performed oligonucleotide microarray analysis in postmortem prefrontal cortices of alcoholics. Among about 12,000 genes represented on microarray, a total of 79 genes showed differential expression changes in alcoholics compared with control subjects, consisting of 54 up- and 25 down-regulated genes.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_003528.2	NP_003519.1	NC_000001.9 range: 148122633..148124855, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0000786	nucleosome	Cellular Component	NAS (1469070)
GO:0005634	nucleus	Cellular Component	IEA
GO:0005694	chromosome	Cellular Component	IEA
GO:0003677	DNA binding	Molecular Function	NAS (1469070)
GO:0005515	protein binding	Molecular Function	IPI (17353931)
GO:0006334	nucleosome assembly	Biological Process	NAS (1469070)
GO:0042742	defense response to bacterium	Biological Process	IEA