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Gene Information
Gene ID:84016
Full Name:glutamate receptor interacting protein 1
Organism:Rattus norvegicus (Rat)
Genetic Location:7q22
Physical Location:59150115-59306130 on NC_005106.2
Gene Type:protein-coding
Human Ortholog:GeneID: 23426    Symbol (Name): GRIP1 (glutamate receptor interacting protein 1)
Ortholog Status:The human GeneID 23426 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:U88572
Fold Change:2.6
Dataset Information
Tissue:Frontal cortex and amygdala
Phenotype:Ethanol response
Publication:Rimondini et al FASEB J. (2002) Long-lasting increase in voluntary ethanol consumption and transcriptional regulation in the rat brain after intermittent exposure to alcohol. PubMed
Summary:Here we demonstrate that rats subjected to repeated cycles of intoxication and withdrawal develop a marked and long-lasting increase in voluntary ethanol intake. Exposure-induced but not spontaneous alcohol intake is antagonized by acamprosate, a compound clinically effective in human alcoholism. Expression analysis of cingulate cortex and amygdala reveals a set of long-term up-regulated transcripts in this model. Here lists the gene expression changes 3 wk after termination of 7 wk of intermittent ethanol exposure. Fold change values are ethanol exposed vs. control rats.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_032069.1NP_114458.1NC_005106.2 range: 59150115..59306130
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0045121membrane raftCellular ComponentISS
GO:0005515protein bindingMolecular FunctionISS
GO:0007399nervous system developmentBiological ProcessIMP (11931740)
GO:0008104protein localizationBiological ProcessISS
Other Database Cross Links
NCBI Entrez Gene:84016