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Gene Information
Gene ID:8788
Symbol:DLK1
Full Name:delta-like 1 homolog (Drosophila)
Alias:DLK|FA1|PREF1|Pref-1|ZOG|pG2
Organism:Homo sapiens (Human)
Chromosome:14
Genetic Location:14q32
Physical Location:100263005-100271212 on NC_000014.7
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:DLK1
Original ID2:T49117
Dataset Information
Name:11093800
Method:Microarray
Tissue:SH-SY5Y neuroblastoma cells
Phenotype:Ethanol response
Publication:Thibault et al. Mol Pharmacol. (2000) Expression profiling of neural cells reveals specific patterns of ethanol-responsive gene expression. PubMed
Summary:We used oligonucleotide arrays to study nearly 6000 genes in human SH-SY5Y neuroblastoma cells exposed to chronic ethanol. A set of 42 genes had consistently increased or decreased mRNA abundance after 3 days of ethanol treatment.
Gene Information
Original ID1:DLK1
Dataset Information
Name:Literature Search
Method:Literature search
Summary:We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_003836.4NP_003827.3NC_000014.7 range: 100263005..100271212
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005615extracellular spaceCellular ComponentTAS (7925474)
GO:0005625soluble fractionCellular ComponentTAS (7925474)
GO:0016020membraneCellular ComponentIEA
GO:0016021integral to membraneCellular ComponentTAS (8095043)
GO:0003674molecular_functionMolecular FunctionND
GO:0005509calcium ion bindingMolecular FunctionIEA
GO:0007275multicellular organismal developmentBiological ProcessTAS (8500166)
Other Database Cross Links
NCBI Entrez Gene:8788
HGNC:2907
Ensembl:ENSG00000185559
MIM:176290
HPRD:01446
HuGE Navigator:8788
dbSNP:DLK1
GeneCard:DLK1
AceView:DLK1