Logo
Home Search BLAST Integration Document Link Support Citation

Gene Information
Gene ID:998
Symbol:CDC42
Full Name:cell division cycle 42 (GTP binding protein, 25kDa)
Alias:CDC42Hs|G25K
Organism:Homo sapiens (Human)
Chromosome:1
Genetic Location:1p36.1
Physical Location:22251706-22292022 on NC_000001.9
Gene Type:protein-coding
Orthologs:This gene has Mouse: 12540 ortholog(s) in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:CDC42
Dataset Information
Name:Literature Search
Method:Literature search
Summary:We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_001039802.1NP_001034891.1NC_000001.9 range: 22251706..22292022
NM_001791.3NP_001782.1NC_000001.9 range: 22251706..22292022
NM_044472.2NP_426359.1NC_000001.9 range: 22251706..22292022
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0030175filopodiumCellular ComponentIDA (11035016)
GO:0005886plasma membraneCellular ComponentIDA (11260256)
GO:0005829cytosolCellular ComponentEXP (14505571|16407834)
GO:0005737cytoplasmCellular ComponentIDA (11260256)
GO:0005622intracellularCellular ComponentIEA
GO:0005525GTP bindingMolecular FunctionIEA
GO:0005515protein bindingMolecular FunctionIPI (10587647|11035016)
GO:0003924GTPase activityMolecular FunctionTAS (11035016)
GO:0000166nucleotide bindingMolecular FunctionIEA
GO:0031333negative regulation of protein complex assemblyBiological ProcessIPI (11584266)
GO:0031274positive regulation of pseudopodium formationBiological ProcessIDA (11035016)
GO:0030225macrophage differentiationBiological ProcessTAS (11260256)
GO:0030036actin cytoskeleton organization and biogenesisBiological ProcessIDA (11035016)
GO:0007264small GTPase mediated signal transductionBiological ProcessIEA
GO:0007163establishment and/or maintenance of cell polarityBiological ProcessTAS (11260256)
GO:0051301cell divisionBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:998
HGNC:1736
Ensembl:ENSG00000070831
MIM:116952
HPRD:00309
HuGE Navigator:998
dbSNP:CDC42
GeneCard:CDC42
AceView:CDC42