PAHKB

Animal Model	PH type	Strain
Wild type/Normal	PH	C57BL6/J
Wild type/Normal	PH	C57BL6/J
5-LO knockout	HPH	C57BL6/J
PGI2 synthase overexpression	HPH	C57BL6/J
HO-1 knockout	HPH	C57BL6/J
SMC BMPR2 dom. neg	PH	FVB/N
BMPR2 +/-	PH	C57BL6/J
BMPR2 +/- with Ad5LO overexpression	PH	C57BL6/J
5-HTT overexpression	PH	C57BL6/J
VIP knockout	PAH	C57BL6/J
PVEC BMPR-/- knockout	PAH	R26R
SMC PPARgamma -/- knockout	PH	C57BL6/J
SMC BMPR2 +-	PH	C57BL6/J
SMC BMPR2+- with MCT + Ad5LO	PH	C57BL6/J
Eln -/-	PH	C57BL/6
SMC BMPR2 R899X	PH	FVB/N
Wildtype with OVA exposure	PAH	C57BL/6
TPH1 -/- knockout with dexfenflur.	PH	C57BL6/J
Human SERT+ with dexfenflur	PH	C57BL6/J
Wild type with dexfenflur	PH	C57BL6/J
Notch -/- knockout	PAH	C57BL6/J
IL-6 overexpression	PH	C57BL6/J
SMC ID-1 -/- knockout	HPH	C57BL6/J
Nogo -/- knockout	PH	C57BL6/J
A2AR -/- knockout	PAH	C57BL6/J
Wild type with imatinib	HPH	C57BL6/J
CTGF overexpression	PH	N/A
Human MMP9 overexpression	PAH	C57BL6/J
Human MMP9 overexpression with MCT	PAH	C57BL6/J
RKIP -/-	HPH	C57BL6/J
SMC BMPR2 R899X	PH	FVB/N
SMC BMPR2 R899X with fasudil	PH	FVB/N
COX-2 -/- knockout	PH	C57BL6/J
COX-2 -/- knockout with MCT	PH	C57BL6/J
Human HO-1 overexpression	HPH	FVB
Apelin knockout	HPH	SV129
Wild type/Normal	HPH	C57BL6/J
P53 knockout	HPH	C57BL6/J
Wild type/Normal with SU5416	PAH	C57BL6/J
PVEC BMPR -/- knockout	PAH	R26R
PVEC BMPR-/- knockout with SCH527123	PAH	R26R
Calpain-4 knockout	PH	CD1-B6.Cg 5Amc/J
OX40L overexpression	PH	C57BL6
S. Mansoni parasitic infection	PH	C57BL6
Deficient in GTP-CH1/BH4	PH	Hph-1 mouse
eNOS +/-	HPH	N/A
eNOS -/-	HPH	N/A
Cav1 -/-	PH	N/A
Cav1 -/-	PH	N/A
TAFI -/-	PH	N/A
IL6 overexpression	PH	N/A
Mkp-1 -/-	PH	N/A
A genetic rat model of ET(B) receptor deficiency (transgenic sl/sl)	HPH	N/A