Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase

Found 10 literature records

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Entrez IDDescription
5727Developmental defects in Gorlin syndrome related to a putative tumor suppressor gene on chromosome 9.
5727Expression of the PTCH1 tumor suppressor gene is regulated by alternative promoters and a single functional Gli-binding site.
5325The candidate tumor suppressor gene ZAC is involved in keratinocyte differentiation and its expression is lost in basal cell carcinomas.
4851"in UV-related squamous cell photocarcinogenesis Notch 1 downregulation could mirror a tumor suppressor function of the receptor, in sun-protected squamous cell carcinomas Notch 1 was upregulated"
5727Heterozygous mutations in the tumor suppressor gene PATCHED provoke basal cell carcinoma-like features in human organotypic skin cultures.
5727Tumor suppressor gene co-operativity in compound Patched1 and suppressor of fused heterozygous mutant mice.
7157these results point toward a correlation between GST P1 polymorphisms and lack of TP53 expression in cutaneous basal cell carcinoma(BCC) suggesting perhaps a crucial role for the GST P1 in expression of TP53 tumor suppressor in BCC.
374654"These studies establish Sufu and Kif7 as crucial components in the regulation of Gli2 localization and activity, and illustrate their overlapping functions in skin development and tumor suppression."
51684"These studies establish Sufu and Kif7 as crucial components in the regulation of Gli2 localization and activity, and illustrate their overlapping functions in skin development and tumor suppression."
8643"Isolation and characterization of human patched 2 (PTCH2), a putative tumour suppressor gene inbasal cell carcinoma and medulloblastoma on chromosome 1p32."

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