 |
| |
| |
| |
| |
| |
| |
|
| TissGeneSummary for NT5C1B |
 Gene summary |
| Basic gene information | Gene symbol | NT5C1B |
| Gene name | ||
| Synonyms | ||
| Cytomap | UCSC genome browser: | |
| Type of gene | ||
| RefGenes | ||
| Description | ||
| Modification date | ||
| dbXrefs | ||
| Protein | UniProt: go to UniProt's Cross Reference DB Table | |
| Expression | CleanEX: HS_NT5C1B | |
| BioGPS: 100526794 | ||
| Pathway | NCI Pathway Interaction Database: NT5C1B | |
| KEGG: NT5C1B | ||
| REACTOME: NT5C1B | ||
| Pathway Commons: NT5C1B | ||
| Context | iHOP: NT5C1B | |
| ligand binding site mutation search in PubMed: NT5C1B | ||
| UCL Cancer Institute: NT5C1B | ||
| Assigned class in TissGDB* | C | |
| Included tissue-specific gene expression resources | HPA,GTEx | |
| Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx) | Testis | |
| Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA) | TGCT | |
| Reference showing the relevant tissue of NT5C1B | ||
| Description by TissGene annotations | ||
| * Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C. |
| Gene ontology having evidence of Inferred from Direct Assay (IDA) from Entrez |
| GO ID | GO term | PubMed ID |
| Top |
| TissGeneExp for NT5C1B |
| Gene expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
 |
| Gene isoform expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01) |
 |
| Gene expressions across normal tissues of GTEx data (GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct) - Here, we shows the matched tissue types only among our 28 cancer types. |
 |
| Different expressions across 14 cancer types with more than 10 samples between matched tumors and normals (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
 |
| - Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05) |
| Cancer type | Mean(exp) in tumor | Mean(exp) in matched normal | Log2FC | P-val. | FDR |
| Top |
| TissGene-miRNA for NT5C1B |
| Significantly anti-correlated miRNAs of TissGene across 28 cancer types (Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016) (TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21) (TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16) (Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25)) |
| Cancer type | miRNA id | miRNA accession | P-val. | Coeff. | # samples |
| Top |
| TissGeneMut for NT5C1B |
| TissGeneSNV for NT5C1B |
| nsSNV counts per each loci. Different colors of circles represent different cancer types. Circle size denotes number of samples. (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) * Click on the image to enlarge it in a new window. |
 |
 |
| Somatic nucleotide variants of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of mutated samples) The numbers in parentheses are numbers of samples with mutation (nsSNVs). (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) |
 |
| - nsSNVs sorted by frequency. |
| AAchange | Cancer type | # samples |
| p.S176L | SKCM | 2 |
| p.E29K | SKCM | 2 |
| p.E268K | SKCM | 2 |
| p.N152S | HNSC | 1 |
| p.R463H | STAD | 1 |
| p.Y397H | KIRC | 1 |
| p.D525N | SKCM | 1 |
| p.R332W | COAD | 1 |
| p.R36H | LGG | 1 |
| p.A410V | PRAD | 1 |
| p.K71T | SKCM | 1 |
| p.C436* | LUAD | 1 |
| p.R156H | CESC | 1 |
| p.Y310C | UCS | 1 |
| p.D372H | LUAD | 1 |
| p.R201C | SKCM | 1 |
| p.H85Y | SKCM | 1 |
| p.R409W | STAD | 1 |
| p.W240* | LIHC | 1 |
| p.D217N | SKCM | 1 |
| p.L124P | DLBC | 1 |
| p.S253T | LUAD | 1 |
| p.R463H | HNSC | 1 |
| p.A132D | UCEC | 1 |
| p.A358V | STAD | 1 |
| p.R494C | PRAD | 1 |
| p.H339Y | SKCM | 1 |
| p.R480H | STAD | 1 |
| p.G191R | SKCM | 1 |
| p.R145C | THYM | 1 |
| p.E173* | UCEC | 1 |
| p.D312H | LUAD | 1 |
| p.R222C | THYM | 1 |
| p.E231K | SKCM | 1 |
| p.G14R | UCEC | 1 |
| p.H520Y | SKCM | 1 |
| p.R204Q | LUAD | 1 |
| p.S134T | BRCA | 1 |
| p.A364V | BLCA | 1 |
| p.R64C | OV | 1 |
| p.D427V | LUAD | 1 |
| p.E591K | BLCA | 1 |
| p.E561K | HNSC | 1 |
| p.R36C | UCEC | 1 |
| p.W61X | SKCM | 1 |
| p.G191E | SKCM | 1 |
| p.L103M | LUAD | 1 |
| p.R261H | HNSC | 1 |
| p.D277N | STAD | 1 |
| p.D153Y | PAAD | 1 |
| p.A386V | SKCM | 1 |
| p.D322G | STAD | 1 |
| p.W61* | SKCM | 1 |
| p.E206Q | TGCT | 1 |
| p.R526W | UCEC | 1 |
| p.A361T | LUAD | 1 |
| p.R201H | HNSC | 1 |
| p.E151K | SKCM | 1 |
| p.L366H | BLCA | 1 |
| p.A375V | STAD | 1 |
| p.P47Q | ESCA | 1 |
| p.P470H | BLCA | 1 |
| p.L376V | UCEC | 1 |
| p.D140N | SKCM | 1 |
| p.R403H | HNSC | 1 |
| p.M15I | SKCM | 1 |
| p.N212S | HNSC | 1 |
| p.D216N | HNSC | 1 |
| p.Q43E | KIRP | 1 |
| p.S61L | UCEC | 1 |
| p.Q120E | KIRP | 1 |
| p.A481V | COAD | 1 |
| p.D500G | COAD | 1 |
| p.Y355X | LIHC | 1 |
| p.E531K | BLCA | 1 |
| p.Q184* | LUAD | 1 |
| p.R43C | READ | 1 |
| p.Y387C | UCS | 1 |
| p.S314C | LUAD | 1 |
| p.R36C | COAD | 1 |
| p.T135M | COAD | 1 |
| p.P101S | SKCM | 1 |
| p.E283Q | TGCT | 1 |
| p.E266K | BRCA | 1 |
| p.E213D | HNSC | 1 |
| p.G340S | ESCA | 1 |
| p.S65F | SKCM | 1 |
| p.Q271R | STAD | 1 |
| p.P197T | PAAD | 1 |
| p.D76Y | PAAD | 1 |
| p.D169N | SKCM | 1 |
| p.S69Y | STAD | 1 |
| p.E501K | SKCM | 1 |
| p.W317X | LIHC | 1 |
| p.R228Q | STAD | 1 |
| p.E23Q | CESC | 1 |
| p.K325N | BRCA | 1 |
| p.P120T | PAAD | 1 |
| p.R245Q | STAD | 1 |
| p.G408E | SKCM | 1 |
| p.A121T | COAD | 1 |
| p.R294S | LUAD | 1 |
| p.D450H | BRCA | 1 |
| p.M41I | SKCM | 1 |
| p.E561K | UCEC | 1 |
| p.S196F | SKCM | 1 |
| p.R565P | LUAD | 1 |
| p.F420L | SKCM | 1 |
| p.R81H | LGG | 1 |
| p.Y474H | KIRC | 1 |
| p.V296I | HNSC | 1 |
| p.L56F | SKCM | 1 |
| p.E213K | SKCM | 1 |
| p.R144Q | LUAD | 1 |
| p.S254C | LUAD | 1 |
| p.E273K | SKCM | 1 |
| p.R127Q | COAD | 1 |
| p.E151D | BLCA | 1 |
| p.F466V | LIHC | 1 |
| p.G263S | ESCA | 1 |
| p.I517T | LGG | 1 |
| p.I266V | THCA | 1 |
| p.Q124* | LUAD | 1 |
| p.R144W | STAD | 1 |
| p.E163K | SKCM | 1 |
| p.R162W | COAD | 1 |
| p.G71E | SKCM | 1 |
| p.E501K | HNSC | 1 |
| p.A304V | BLCA | 1 |
| Top |
| TissGeneCNV for NT5C1B |
| Copy number variations of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of CNV samples) (TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16) |
 |
| Top |
| TissGeneFusions for NT5C1B |
| Fusion genes including TissGene (ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01) |
| Database | Src | Cancer type | Sample | Fusion gene | ORF | 5'-gene BP | 3'-gene BP |
| Top |
| TissGeneNet for NT5C1B |
| Co-expressed gene networks based on protein-protein interaction data (CePIN) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (PINA2 ppi data) |
| Top |
| TissGeneProg for NT5C1B |
| Kaplan-Meier plots with logrank tests of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image to enlarge it in a new window. |
 |
| Kaplan-Meier plots with logrank test of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
 |
| Forest plot of Cox proportional hazard ratio (HR) and 95% CI of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
 |
| Forest plot of Cox proportional hazard ratio (HR) and 95% CI of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
 |
| Top |
| TissGeneClin for NT5C1B |
| TissGeneDrug for NT5C1B |
| Drug information targeting TissGene (DrugBank Version 5.0.6, 2017-04-01) |
| DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Top |
| TissGeneDisease for NT5C1B |
| Disease information associated with TissGene (DisGeNet, 2016-06-01) |
| Disease ID | Disease name | # pubmeds | Source |
| umls:C0003125 | Anorexia Nervosa | 1 | BeFree |
| umls:C0007222 | Cardiovascular Diseases | 1 | GAD |
| umls:C0015672 | Fatigue | 1 | GAD |
| umls:C0021603 | Sleep Initiation and Maintenance Disorders | 1 | GAD |
| umls:C0851578 | Sleep Disorders | 1 | GAD |
| umls:C2267227 | Bulimia Nervosa | 1 | BeFree |
Copyright 2016-Present - The University of Texas Health Science Center at Houston (UTHealth) Web File Viewing | How to Report, Fraud, Waste and Abuse | State of Texas | Statewide Search | Texas Homeland Security | Site Policies |