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| TissGeneSummary for FAM47A |
 Gene summary |
| Basic gene information | Gene symbol | FAM47A |
| Gene name | family with sequence similarity 47, member A | |
| Synonyms | - | |
| Cytomap | UCSC genome browser: Xp21.1 | |
| Type of gene | protein-coding | |
| RefGenes | NM_203408.3, | |
| Description | protein FAM47A | |
| Modification date | 20141207 | |
| dbXrefs | HGNC : HGNC | |
| Ensembl : ENSG00000185448 | ||
| HPRD : 10947 | ||
| Vega : OTTHUMG00000021339 | ||
| Protein | UniProt: go to UniProt's Cross Reference DB Table | |
| Expression | CleanEX: HS_FAM47A | |
| BioGPS: 158724 | ||
| Pathway | NCI Pathway Interaction Database: FAM47A | |
| KEGG: FAM47A | ||
| REACTOME: FAM47A | ||
| Pathway Commons: FAM47A | ||
| Context | iHOP: FAM47A | |
| ligand binding site mutation search in PubMed: FAM47A | ||
| UCL Cancer Institute: FAM47A | ||
| Assigned class in TissGDB* | C | |
| Included tissue-specific gene expression resources | HPA,GTEx | |
| Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx) | Testis | |
| Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA) | TGCT | |
| Reference showing the relevant tissue of FAM47A | ||
| Description by TissGene annotations | ||
| * Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C. |
| Gene ontology having evidence of Inferred from Direct Assay (IDA) from Entrez |
| GO ID | GO term | PubMed ID |
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| TissGeneExp for FAM47A |
| Gene expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
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| Gene isoform expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01) |
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| Gene expressions across normal tissues of GTEx data (GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct) - Here, we shows the matched tissue types only among our 28 cancer types. |
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| Different expressions across 14 cancer types with more than 10 samples between matched tumors and normals (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
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| - Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05) |
| Cancer type | Mean(exp) in tumor | Mean(exp) in matched normal | Log2FC | P-val. | FDR |
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| TissGene-miRNA for FAM47A |
| Significantly anti-correlated miRNAs of TissGene across 28 cancer types (Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016) (TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21) (TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16) (Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25)) |
| Cancer type | miRNA id | miRNA accession | P-val. | Coeff. | # samples |
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| TissGeneMut for FAM47A |
| TissGeneSNV for FAM47A |
| nsSNV counts per each loci. Different colors of circles represent different cancer types. Circle size denotes number of samples. (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) * Click on the image to enlarge it in a new window. |
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| Somatic nucleotide variants of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of mutated samples) The numbers in parentheses are numbers of samples with mutation (nsSNVs). (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) |
 |
| - nsSNVs sorted by frequency. |
| AAchange | Cancer type | # samples |
| p.E378K | SKCM | 3 |
| p.Y60C | LUAD | 2 |
| p.R576Q | SKCM | 2 |
| p.P713L | SKCM | 2 |
| p.D3N | SKCM | 2 |
| p.S105F | SKCM | 2 |
| p.P573L | SKCM | 2 |
| p.S519* | LUAD | 2 |
| p.R361H | BLCA | 2 |
| p.W705* | SKCM | 2 |
| p.R544C | SKCM | 2 |
| p.G372W | LUSC | 2 |
| p.R518C | SKCM | 2 |
| p.R487Q | READ | 1 |
| p.V595I | CESC | 1 |
| p.S685P | OV | 1 |
| p.M776I | SKCM | 1 |
| p.R255H | BLCA | 1 |
| p.R72C | LUSC | 1 |
| p.R345S | LUAD | 1 |
| p.R37H | COAD | 1 |
| p.T291R | LIHC | 1 |
| p.E726K | SKCM | 1 |
| p.T537N | UCEC | 1 |
| p.K574N | UCS | 1 |
| p.G747C | HNSC | 1 |
| p.E307K | PAAD | 1 |
| p.P317T | HNSC | 1 |
| p.R314C | SKCM | 1 |
| p.L337F | SKCM | 1 |
| p.R412C | SKCM | 1 |
| p.E307K | UCEC | 1 |
| p.P109L | SKCM | 1 |
| p.H246N | LUAD | 1 |
| p.E507D | BRCA | 1 |
| p.R73H | GBM | 1 |
| p.R361H | PCPG | 1 |
| p.D664N | SKCM | 1 |
| p.R576Q | LGG | 1 |
| p.K368N | LUAD | 1 |
| p.H492Y | SKCM | 1 |
| p.D268N | LUAD | 1 |
| p.F58L | LUAD | 1 |
| p.D268Y | LIHC | 1 |
| p.E446Q | LGG | 1 |
| p.R500Q | COAD | 1 |
| p.R551H | LIHC | 1 |
| p.G735V | PRAD | 1 |
| p.K667T | READ | 1 |
| p.C166F | LUAD | 1 |
| p.D443N | SKCM | 1 |
| p.T287A | UCEC | 1 |
| p.G531D | UCEC | 1 |
| p.V118I | COAD | 1 |
| p.P192S | SKCM | 1 |
| p.G619E | SKCM | 1 |
| p.R602G | COAD | 1 |
| p.E158K | SKCM | 1 |
| p.P290A | LIHC | 1 |
| p.H376R | LUSC | 1 |
| p.H479Y | DLBC | 1 |
| p.S476F | SKCM | 1 |
| p.D732N | SKCM | 1 |
| p.E571Q | LUAD | 1 |
| p.V118I | GBM | 1 |
| p.P252A | HNSC | 1 |
| p.R448Q | HNSC | 1 |
| p.Q755* | BLCA | 1 |
| p.V729I | LUAD | 1 |
| p.P63L | SKCM | 1 |
| p.E390K | SKCM | 1 |
| p.W698R | OV | 1 |
| p.P179A | LUAD | 1 |
| p.A88V | SKCM | 1 |
| p.P391L | SKCM | 1 |
| p.P483S | SKCM | 1 |
| p.C188S | SKCM | 1 |
| p.R224L | ACC | 1 |
| p.K405E | LUAD | 1 |
| p.P717S | SKCM | 1 |
| p.A759S | LUAD | 1 |
| p.R277Q | READ | 1 |
| p.E289K | SKCM | 1 |
| p.P183T | LUAD | 1 |
| p.E378K | HNSC | 1 |
| p.E66K | BRCA | 1 |
| p.D275Y | LUAD | 1 |
| p.M658I | LUAD | 1 |
| p.E122K | SKCM | 1 |
| p.E378* | UCEC | 1 |
| p.E205K | SKCM | 1 |
| p.P279L | SKCM | 1 |
| p.A688S | LUAD | 1 |
| p.S570L | SKCM | 1 |
| p.I737V | LIHC | 1 |
| p.L599F | LUAD | 1 |
| p.P297S | SARC | 1 |
| p.G282D | LUAD | 1 |
| p.S685C | LUSC | 1 |
| p.R338C | BRCA | 1 |
| p.R690L | LUAD | 1 |
| p.P237Q | LUAD | 1 |
| p.P42L | SKCM | 1 |
| p.W698* | HNSC | 1 |
| p.E672K | SKCM | 1 |
| p.Q420L | LUAD | 1 |
| p.R370C | UCEC | 1 |
| p.P130S | SKCM | 1 |
| p.P213T | ESCA | 1 |
| p.P462S | HNSC | 1 |
| p.E622K | SKCM | 1 |
| p.P249Q | HNSC | 1 |
| p.P462L | HNSC | 1 |
| p.R314H | ESCA | 1 |
| p.R255C | HNSC | 1 |
| p.G333E | SKCM | 1 |
| p.L77F | HNSC | 1 |
| p.S570L | HNSC | 1 |
| p.R609C | UCEC | 1 |
| p.A88P | STAD | 1 |
| p.P330T | GBM | 1 |
| p.V595A | LIHC | 1 |
| p.E465K | HNSC | 1 |
| p.K549N | LUAD | 1 |
| p.G735E | SKCM | 1 |
| p.P109S | SKCM | 1 |
| p.G180C | HNSC | 1 |
| p.P130L | SKCM | 1 |
| p.P480T | LUAD | 1 |
| p.Q111L | LUAD | 1 |
| p.C298* | PRAD | 1 |
| p.R576Q | LUSC | 1 |
| p.S685Y | UCEC | 1 |
| p.V729I | THCA | 1 |
| p.P179H | LUAD | 1 |
| p.A31V | PRAD | 1 |
| p.R412H | UCEC | 1 |
| p.P79S | SKCM | 1 |
| p.S519P | SARC | 1 |
| p.R371L | LUAD | 1 |
| p.K106T | LUAD | 1 |
| p.R412C | UCEC | 1 |
| p.R518H | STAD | 1 |
| p.E649* | LUSC | 1 |
| p.E193K | LGG | 1 |
| p.G616A | LUAD | 1 |
| p.L730I | UCEC | 1 |
| p.E582* | UCEC | 1 |
| p.R37H | STAD | 1 |
| p.P713S | SKCM | 1 |
| p.A278D | LUAD | 1 |
| p.H567N | LUAD | 1 |
| p.T501M | COAD | 1 |
| p.P225R | LUAD | 1 |
| p.R500W | OV | 1 |
| p.D728N | UCEC | 1 |
| p.V51M | SKCM | 1 |
| p.F76I | STAD | 1 |
| p.K746N | LUAD | 1 |
| p.E292V | LUAD | 1 |
| p.S683L | UCEC | 1 |
| p.F569L | UCEC | 1 |
| p.E160D | UCEC | 1 |
| p.E75K | SKCM | 1 |
| p.E665V | LIHC | 1 |
| p.P79L | LGG | 1 |
| p.R539* | UCEC | 1 |
| p.K746* | LUSC | 1 |
| p.D144Y | HNSC | 1 |
| p.A365V | UCEC | 1 |
| p.E75K | UCEC | 1 |
| p.E292* | LUAD | 1 |
| p.L337V | LUAD | 1 |
| p.R72H | HNSC | 1 |
| p.D57N | LUAD | 1 |
| p.R774C | STAD | 1 |
| p.T230S | UCEC | 1 |
| p.R448W | LGG | 1 |
| p.P366T | LUAD | 1 |
| p.H336N | LUAD | 1 |
| p.R544G | BLCA | 1 |
| p.P290L | SKCM | 1 |
| p.G407A | HNSC | 1 |
| p.G735R | SKCM | 1 |
| p.E649K | SKCM | 1 |
| p.S434P | BRCA | 1 |
| p.Q46H | LUAD | 1 |
| p.R361H | HNSC | 1 |
| p.P713T | OV | 1 |
| p.R371Q | SKCM | 1 |
| p.E533D | STAD | 1 |
| p.E472K | SKCM | 1 |
| p.E593* | HNSC | 1 |
| p.C188F | LUAD | 1 |
| p.K643N | STAD | 1 |
| p.L375P | LUAD | 1 |
| p.R539Q | LGG | 1 |
| p.P401T | LUAD | 1 |
| p.P192L | SKCM | 1 |
| p.A563T | LUSC | 1 |
| p.R326C | HNSC | 1 |
| p.F76I | PRAD | 1 |
| p.H198P | LIHC | 1 |
| p.R538C | UCEC | 1 |
| p.K607E | UVM | 1 |
| p.P633H | LUAD | 1 |
| p.L387R | READ | 1 |
| p.E559K | CESC | 1 |
| p.V118I | KIRC | 1 |
| p.E356K | LUSC | 1 |
| p.K663T | STAD | 1 |
| p.R371W | STAD | 1 |
| p.F631L | SKCM | 1 |
| p.A116T | SKCM | 1 |
| p.R487Q | PAAD | 1 |
| p.R760K | LGG | 1 |
| p.S245C | ESCA | 1 |
| p.S269F | SKCM | 1 |
| p.T194A | LIHC | 1 |
| p.R72H | OV | 1 |
| p.H557Y | SKCM | 1 |
| p.P219L | LUAD | 1 |
| p.S590R | STAD | 1 |
| p.P354S | SKCM | 1 |
| p.R351H | LIHC | 1 |
| p.P213Q | SKCM | 1 |
| p.R345C | SKCM | 1 |
| p.Q755* | LUAD | 1 |
| p.K746N | HNSC | 1 |
| p.E726G | LUAD | 1 |
| p.G372W | HNSC | 1 |
| p.P532L | UCEC | 1 |
| p.H567Q | BRCA | 1 |
| p.D641N | SKCM | 1 |
| p.T537I | SKCM | 1 |
| p.E786* | LUAD | 1 |
| p.C298X | PRAD | 1 |
| p.F668L | UCEC | 1 |
| p.R59C | LUAD | 1 |
| p.R544L | LUAD | 1 |
| p.S92N | UCEC | 1 |
| p.S419R | HNSC | 1 |
| p.R326C | COAD | 1 |
| p.P201S | BLCA | 1 |
| p.R609H | SARC | 1 |
| p.P176H | LUAD | 1 |
| p.R224H | ESCA | 1 |
| p.C445S | LIHC | 1 |
| p.R518G | CESC | 1 |
| p.S490G | HNSC | 1 |
| p.A759G | LUAD | 1 |
| p.S461F | SKCM | 1 |
| p.R690H | LUAD | 1 |
| p.E481K | SKCM | 1 |
| p.R486L | LUSC | 1 |
| p.P558L | STAD | 1 |
| p.N627I | LUSC | 1 |
| p.T218P | HNSC | 1 |
| p.V595I | SKCM | 1 |
| p.W163C | LIHC | 1 |
| p.E593V | LUAD | 1 |
| p.R59H | HNSC | 1 |
| p.R505H | UCEC | 1 |
| p.R73L | LUAD | 1 |
| p.P219L | STAD | 1 |
| p.R283W | STAD | 1 |
| p.E571* | LUSC | 1 |
| p.R346Q | COAD | 1 |
| p.R283W | LGG | 1 |
| p.P471T | LUAD | 1 |
| p.E66K | GBM | 1 |
| p.T177N | HNSC | 1 |
| p.Q671* | LUAD | 1 |
| p.P219L | SKCM | 1 |
| p.H234Y | LIHC | 1 |
| p.L150R | COAD | 1 |
| p.R72L | LUAD | 1 |
| p.R248G | LUAD | 1 |
| p.P195L | SKCM | 1 |
| p.P534L | ESCA | 1 |
| p.R436T | LUAD | 1 |
| p.E284K | THYM | 1 |
| p.A365V | PRAD | 1 |
| p.E586K | SKCM | 1 |
| p.R487Q | KIRP | 1 |
| p.P155S | SKCM | 1 |
| p.S108F | LAML | 1 |
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| TissGeneCNV for FAM47A |
| Copy number variations of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of CNV samples) (TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16) |
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| TissGeneFusions for FAM47A |
| Fusion genes including TissGene (ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01) |
| Database | Src | Cancer type | Sample | Fusion gene | ORF | 5'-gene BP | 3'-gene BP |
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| TissGeneNet for FAM47A |
| Co-expressed gene networks based on protein-protein interaction data (CePIN) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (PINA2 ppi data) |
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| TissGeneProg for FAM47A |
| Kaplan-Meier plots with logrank tests of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image to enlarge it in a new window. |
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| Kaplan-Meier plots with logrank test of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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| Forest plot of Cox proportional hazard ratio (HR) and 95% CI of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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| Forest plot of Cox proportional hazard ratio (HR) and 95% CI of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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| TissGeneClin for FAM47A |
| TissGeneDrug for FAM47A |
| Drug information targeting TissGene (DrugBank Version 5.0.6, 2017-04-01) |
| DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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| TissGeneDisease for FAM47A |
| Disease information associated with TissGene (DisGeNet, 2016-06-01) |
| Disease ID | Disease name | # pubmeds | Source |
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