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| TissGeneSummary for POTEG |
 Gene summary |
| Basic gene information | Gene symbol | POTEG |
| Gene name | ||
| Synonyms | ||
| Cytomap | UCSC genome browser: | |
| Type of gene | ||
| RefGenes | ||
| Description | ||
| Modification date | ||
| dbXrefs | ||
| Protein | UniProt: go to UniProt's Cross Reference DB Table | |
| Expression | CleanEX: HS_POTEG | |
| BioGPS: 653781 | ||
| Pathway | NCI Pathway Interaction Database: POTEG | |
| KEGG: POTEG | ||
| REACTOME: POTEG | ||
| Pathway Commons: POTEG | ||
| Context | iHOP: POTEG | |
| ligand binding site mutation search in PubMed: POTEG | ||
| UCL Cancer Institute: POTEG | ||
| Assigned class in TissGDB* | C | |
| Included tissue-specific gene expression resources | TiGER,GTEx | |
| Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx) | Prostate | |
| Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA) | PRAD | |
| Reference showing the relevant tissue of POTEG | ||
| Description by TissGene annotations | Significant up-regulated DEG TissgsKTS CNV lost TissGeneKTS | |
| * Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C. |
| Gene ontology having evidence of Inferred from Direct Assay (IDA) from Entrez |
| GO ID | GO term | PubMed ID |
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| TissGeneExp for POTEG |
| Gene expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
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| Gene isoform expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01) |
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| Gene expressions across normal tissues of GTEx data (GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct) - Here, we shows the matched tissue types only among our 28 cancer types. |
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| Different expressions across 14 cancer types with more than 10 samples between matched tumors and normals (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
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| - Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05) |
| Cancer type | Mean(exp) in tumor | Mean(exp) in matched normal | Log2FC | P-val. | FDR |
| PRAD | 4.864646886 | 3.763141117 | 1.101505769 | 0.0109 | 0.026322091 |
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| TissGene-miRNA for POTEG |
| Significantly anti-correlated miRNAs of TissGene across 28 cancer types (Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016) (TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21) (TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16) (Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25)) |
| Cancer type | miRNA id | miRNA accession | P-val. | Coeff. | # samples |
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| TissGeneMut for POTEG |
| TissGeneSNV for POTEG |
| nsSNV counts per each loci. Different colors of circles represent different cancer types. Circle size denotes number of samples. (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) * Click on the image to enlarge it in a new window. |
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| Somatic nucleotide variants of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of mutated samples) The numbers in parentheses are numbers of samples with mutation (nsSNVs). (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) |
 |
| - nsSNVs sorted by frequency. |
| AAchange | Cancer type | # samples |
| p.D51N | SKCM | 5 |
| p.D125N | SKCM | 5 |
| p.L379S | BRCA | 3 |
| p.E130K | SKCM | 3 |
| p.D122N | SKCM | 2 |
| p.D412N | SKCM | 2 |
| p.D50N | SKCM | 2 |
| p.H350Y | SKCM | 2 |
| p.M54I | SKCM | 2 |
| p.R136H | GBM | 2 |
| p.R137* | SKCM | 2 |
| p.D50Y | HNSC | 2 |
| p.M129I | SKCM | 2 |
| p.V135I | STAD | 1 |
| p.H49Y | SKCM | 1 |
| p.C103F | LUAD | 1 |
| p.R137Q | GBM | 1 |
| p.W64L | HNSC | 1 |
| p.Q355H | LUAD | 1 |
| p.H86N | LUAD | 1 |
| p.V135I | LUAD | 1 |
| p.R137* | LUAD | 1 |
| p.Q339K | LUSC | 1 |
| p.R95S | HNSC | 1 |
| p.D50H | LUAD | 1 |
| p.M98I | KIRC | 1 |
| p.P119L | SKCM | 1 |
| p.P70S | SKCM | 1 |
| p.H349Q | LUAD | 1 |
| p.L336V | LUAD | 1 |
| p.D87N | UCEC | 1 |
| p.S402F | SKCM | 1 |
| p.D125E | UCEC | 1 |
| p.A53S | LIHC | 1 |
| p.K63* | LIHC | 1 |
| p.M419I | UCEC | 1 |
| p.H134Q | HNSC | 1 |
| p.C65F | UCEC | 1 |
| p.S96R | BLCA | 1 |
| p.S369Y | LUSC | 1 |
| p.D302G | LGG | 1 |
| p.G305R | SKCM | 1 |
| p.K414_splice | LUSC | 1 |
| p.K367N | PAAD | 1 |
| p.G392* | UCEC | 1 |
| p.D219Y | ESCA | 1 |
| p.M98R | THCA | 1 |
| p.K77N | LUSC | 1 |
| p.C109S | LUAD | 1 |
| p.P235S | SKCM | 1 |
| p.G118C | LUAD | 1 |
| p.E394G | ESCA | 1 |
| p.W71C | LUAD | 1 |
| p.I353M | UCEC | 1 |
| p.P235S | LUSC | 1 |
| p.R58G | BLCA | 1 |
| p.K26N | DLBC | 1 |
| p.M54I | BLCA | 1 |
| p.S115R | KIRC | 1 |
| p.G121R | SKCM | 1 |
| p.N372S | UCEC | 1 |
| p.L253S | UCEC | 1 |
| p.G239E | SKCM | 1 |
| p.K23N | CESC | 1 |
| p.K114N | BLCA | 1 |
| p.Q334* | LUAD | 1 |
| p.P107S | LUAD | 1 |
| p.D85N | LUAD | 1 |
| p.D51N | CHOL | 1 |
| p.G411S | LUAD | 1 |
| p.R136H | STAD | 1 |
| p.V135I | HNSC | 1 |
| p.L336I | LUAD | 1 |
| p.V346L | HNSC | 1 |
| p.P107H | HNSC | 1 |
| p.S83F | SKCM | 1 |
| p.D51N | KIRP | 1 |
| p.W27R | UCEC | 1 |
| p.W71L | HNSC | 1 |
| p.W120L | LUAD | 1 |
| p.E130* | LUSC | 1 |
| p.A345V | HNSC | 1 |
| p.M365T | GBM | 1 |
| p.R110W | LUSC | 1 |
| p.S59R | LUAD | 1 |
| p.R58S | LUSC | 1 |
| p.W71C | HNSC | 1 |
| p.F106L | LIHC | 1 |
| p.W120* | BLCA | 1 |
| p.E237Q | SARC | 1 |
| p.H349N | LUAD | 1 |
| p.G39S | SARC | 1 |
| p.R136H | BLCA | 1 |
| p.Q355K | LUAD | 1 |
| p.G121E | SKCM | 1 |
| p.L57R | ESCA | 1 |
| p.E130K | LUAD | 1 |
| p.S89F | HNSC | 1 |
| p.H349N | LUSC | 1 |
| p.Y123C | STAD | 1 |
| p.D48N | LUSC | 1 |
| p.W120S | HNSC | 1 |
| p.Q403* | SKCM | 1 |
| p.V368F | ESCA | 1 |
| p.K63R | STAD | 1 |
| p.R137Q | LUAD | 1 |
| p.D125Y | LUAD | 1 |
| p.T56S | PAAD | 1 |
| p.D50G | STAD | 1 |
| p.M419I | SKCM | 1 |
| p.S59N | UCEC | 1 |
| p.R136C | UCEC | 1 |
| p.P455L | UCEC | 1 |
| p.G99V | SKCM | 1 |
| p.R136H | PAAD | 1 |
| p.H49D | HNSC | 1 |
| p.Y133* | STAD | 1 |
| p.P119L | LUAD | 1 |
| p.D51N | STAD | 1 |
| p.P375T | LUAD | 1 |
| p.G113D | PRAD | 1 |
| p.S12F | BRCA | 1 |
| p.D50N | UCS | 1 |
| p.R136H | OV | 1 |
| p.D88N | SKCM | 1 |
| p.G118V | LUAD | 1 |
| p.H134R | STAD | 1 |
| p.M54I | LUSC | 1 |
| p.K414Q | LUAD | 1 |
| p.E266K | UCEC | 1 |
| p.S46F | SKCM | 1 |
| p.R21I | UCEC | 1 |
| p.D124N | BLCA | 1 |
| p.S115C | LUAD | 1 |
| p.S369Y | KIRC | 1 |
| p.G74V | LUAD | 1 |
| p.S52F | CESC | 1 |
| p.W64L | LUAD | 1 |
| p.V368I | LIHC | 1 |
| p.R58S | LUAD | 1 |
| p.Q364R | BLCA | 1 |
| p.S115R | LUAD | 1 |
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| TissGeneCNV for POTEG |
| Copy number variations of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of CNV samples) (TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16) |
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| TissGeneFusions for POTEG |
| Fusion genes including TissGene (ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01) |
| Database | Src | Cancer type | Sample | Fusion gene | ORF | 5'-gene BP | 3'-gene BP |
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| TissGeneNet for POTEG |
| Co-expressed gene networks based on protein-protein interaction data (CePIN) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (PINA2 ppi data) |
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| TissGeneProg for POTEG |
| Kaplan-Meier plots with logrank tests of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image to enlarge it in a new window. |
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| Kaplan-Meier plots with logrank test of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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| Forest plot of Cox proportional hazard ratio (HR) and 95% CI of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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| Forest plot of Cox proportional hazard ratio (HR) and 95% CI of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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| TissGeneClin for POTEG |
| TissGeneDrug for POTEG |
| Drug information targeting TissGene (DrugBank Version 5.0.6, 2017-04-01) |
| DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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| TissGeneDisease for POTEG |
| Disease information associated with TissGene (DisGeNet, 2016-06-01) |
| Disease ID | Disease name | # pubmeds | Source |
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