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TissGeneSummary for RASL10A |
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Basic gene information | Gene symbol | RASL10A |
Gene name | RAS-like, family 10, member A | |
Synonyms | RRP22 | |
Cytomap | UCSC genome browser: 22q12.2 | |
Type of gene | protein-coding | |
RefGenes | NM_001007279.1, NM_006477.4, | |
Description | ras-like protein RRP22ras-like protein family member 10Aras-related protein on chromosome 22 | |
Modification date | 20141207 | |
dbXrefs | MIM : 602220 | |
HGNC : HGNC | ||
Ensembl : ENSG00000100276 | ||
HPRD : 03744 | ||
Vega : OTTHUMG00000151106 | ||
Protein | UniProt: go to UniProt's Cross Reference DB Table | |
Expression | CleanEX: HS_RASL10A | |
BioGPS: 10633 | ||
Pathway | NCI Pathway Interaction Database: RASL10A | |
KEGG: RASL10A | ||
REACTOME: RASL10A | ||
Pathway Commons: RASL10A | ||
Context | iHOP: RASL10A | |
ligand binding site mutation search in PubMed: RASL10A | ||
UCL Cancer Institute: RASL10A | ||
Assigned class in TissGDB* | C | |
Included tissue-specific gene expression resources | ||
Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx) | Brain | |
Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA) | GBM,LGG | |
Reference showing the relevant tissue of RASL10A | ||
Description by TissGene annotations | Protective TissGene in OS Protective TissGene in RFS Cancer gene Fused withTSGene |
* Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C. |
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GO ID | GO term | PubMed ID |
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TissGeneExp for RASL10A |
![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
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![]() (TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01) |
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![]() (GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct) - Here, we shows the matched tissue types only among our 28 cancer types. |
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![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
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- Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05) |
Cancer type | Mean(exp) in tumor | Mean(exp) in matched normal | Log2FC | P-val. | FDR |
BRCA | -0.21925745 | 1.869895182 | -2.089152632 | 6.20E-22 | 5.12E-21 |
LUAD | -1.184858176 | -0.112354728 | -1.072503448 | 1.01E-08 | 4.54E-08 |
LUSC | -1.195501516 | -0.030193673 | -1.165307843 | 1.40E-08 | 4.34E-08 |
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TissGene-miRNA for RASL10A |
![]() (Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016) (TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21) (TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16) (Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25)) |
Cancer type | miRNA id | miRNA accession | P-val. | Coeff. | # samples |
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TissGeneMut for RASL10A |
TissGeneSNV for RASL10A |
![]() Different colors of circles represent different cancer types. Circle size denotes number of samples. (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) * Click on the image to enlarge it in a new window. |
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![]() (X-axis: cancer type and Y-axis: % of mutated samples) The numbers in parentheses are numbers of samples with mutation (nsSNVs). (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) |
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- nsSNVs sorted by frequency. |
AAchange | Cancer type | # samples |
p.R149P | HNSC | 1 |
p.V92I | PRAD | 1 |
p.P98L | SKCM | 1 |
p.W81C | BLCA | 1 |
p.S100I | UCEC | 1 |
p.P116L | STAD | 1 |
p.K105M | LUAD | 1 |
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TissGeneCNV for RASL10A |
![]() (TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16) |
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TissGeneFusions for RASL10A |
![]() (ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01) |
Database | Src | Cancer type | Sample | Fusion gene | ORF | 5'-gene BP | 3'-gene BP |
Chimerdb3.0 | ChiTaRs | NA | AI880234 | RASL10A-RASL10A | chr22:29709497 | chr22:29709009 |
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TissGeneNet for RASL10A |
![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (PINA2 ppi data) |
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TissGeneProg for RASL10A |
![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image to enlarge it in a new window. |
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![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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TissGeneClin for RASL10A |
TissGeneDrug for RASL10A |
![]() (DrugBank Version 5.0.6, 2017-04-01) |
DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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TissGeneDisease for RASL10A |
![]() (DisGeNet, 2016-06-01) |
Disease ID | Disease name | # pubmeds | Source |
umls:C0017638 | Glioma | 2 | BeFree |
umls:C0017636 | Glioblastoma | 1 | BeFree |
umls:C0555198 | Malignant Glioma | 1 | BeFree |
umls:C1709246 | Non-Neoplastic Disorder | 1 | BeFree |