TissGeneSummary for MAGEB16 |
Gene summary |
Basic gene information | Gene symbol | MAGEB16 |
Gene name | melanoma antigen family B, 16 | |
Synonyms | - | |
Cytomap | UCSC genome browser: Xp21.1 | |
Type of gene | protein-coding | |
RefGenes | NM_001099921.1, | |
Description | MAGE-B16 antigenmelanoma antigen family B, 16 (pseudogene)melanoma-associated antigen B16 | |
Modification date | 20141207 | |
dbXrefs | MIM : 300762 | |
HGNC : HGNC | ||
Ensembl : ENSG00000189023 | ||
Vega : OTTHUMG00000021348 | ||
Protein | UniProt: go to UniProt's Cross Reference DB Table | |
Expression | CleanEX: HS_MAGEB16 | |
BioGPS: 139604 | ||
Pathway | NCI Pathway Interaction Database: MAGEB16 | |
KEGG: MAGEB16 | ||
REACTOME: MAGEB16 | ||
Pathway Commons: MAGEB16 | ||
Context | iHOP: MAGEB16 | |
ligand binding site mutation search in PubMed: MAGEB16 | ||
UCL Cancer Institute: MAGEB16 | ||
Assigned class in TissGDB* | C | |
Included tissue-specific gene expression resources | HPA,GTEx | |
Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx) | Testis | |
Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA) | TGCT | |
Reference showing the relevant tissue of MAGEB16 | ||
Description by TissGene annotations | TissgsKTS CNV lost TissGeneKTS |
* Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C. |
Gene ontology having evidence of Inferred from Direct Assay (IDA) from Entrez |
GO ID | GO term | PubMed ID |
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TissGeneExp for MAGEB16 |
Gene expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
Gene isoform expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01) |
Gene expressions across normal tissues of GTEx data (GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct) - Here, we shows the matched tissue types only among our 28 cancer types. |
Different expressions across 14 cancer types with more than 10 samples between matched tumors and normals (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
- Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05) |
Cancer type | Mean(exp) in tumor | Mean(exp) in matched normal | Log2FC | P-val. | FDR |
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TissGene-miRNA for MAGEB16 |
Significantly anti-correlated miRNAs of TissGene across 28 cancer types (Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016) (TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21) (TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16) (Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25)) |
Cancer type | miRNA id | miRNA accession | P-val. | Coeff. | # samples |
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TissGeneMut for MAGEB16 |
TissGeneSNV for MAGEB16 |
nsSNV counts per each loci. Different colors of circles represent different cancer types. Circle size denotes number of samples. (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) * Click on the image to enlarge it in a new window. |
Somatic nucleotide variants of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of mutated samples) The numbers in parentheses are numbers of samples with mutation (nsSNVs). (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) |
- nsSNVs sorted by frequency. |
AAchange | Cancer type | # samples |
p.M130I | SKCM | 2 |
p.M164I | SKCM | 2 |
p.V31I | SKCM | 1 |
p.E261K | SKCM | 1 |
p.T189I | BLCA | 1 |
p.Q46* | CESC | 1 |
p.S268C | LUAD | 1 |
p.G199S | LUAD | 1 |
p.D94V | UCEC | 1 |
p.E82K | BLCA | 1 |
p.A312S | LGG | 1 |
p.V209F | LUAD | 1 |
p.S41F | SKCM | 1 |
p.E148K | SKCM | 1 |
p.V234L | SARC | 1 |
p.V27I | READ | 1 |
p.R272Q | SKCM | 1 |
p.R219H | PAAD | 1 |
p.P61T | BRCA | 1 |
p.E63K | SKCM | 1 |
p.R247K | BLCA | 1 |
p.Y190* | LUSC | 1 |
p.M288I | SKCM | 1 |
p.V265E | LUAD | 1 |
p.E93K | SKCM | 1 |
p.D147G | UCEC | 1 |
p.I250M | LUAD | 1 |
p.F151I | SARC | 1 |
p.M248I | COAD | 1 |
p.T232M | DLBC | 1 |
p.K32R | LIHC | 1 |
p.G244E | SKCM | 1 |
p.E91D | CESC | 1 |
p.P18T | LUAD | 1 |
p.Q90K | LUSC | 1 |
p.R247K | GBM | 1 |
p.C69F | THYM | 1 |
p.A112V | LUAD | 1 |
p.G233R | HNSC | 1 |
p.Q115H | UCEC | 1 |
p.Q115L | LUAD | 1 |
p.V121L | LUAD | 1 |
p.F166C | SKCM | 1 |
p.E224K | SKCM | 1 |
p.R304Q | CESC | 1 |
p.S99* | BLCA | 1 |
p.R30S | LUAD | 1 |
p.L276M | COAD | 1 |
p.S88N | SKCM | 1 |
p.L156Q | LUAD | 1 |
p.L156R | OV | 1 |
p.A310V | STAD | 1 |
p.P105L | SKCM | 1 |
p.E163X | COAD | 1 |
p.L125Q | LUAD | 1 |
p.D13N | LUSC | 1 |
p.A220V | UCEC | 1 |
p.D169Y | LUAD | 1 |
p.S60R | PAAD | 1 |
p.P61S | KIRC | 1 |
p.F151Y | GBM | 1 |
p.E21K | BRCA | 1 |
p.T176S | HNSC | 1 |
p.D101E | OV | 1 |
p.S99L | STAD | 1 |
p.T176R | HNSC | 1 |
p.P105L | LGG | 1 |
p.A33P | LUAD | 1 |
p.R9X | STAD | 1 |
p.A310E | HNSC | 1 |
p.T189S | LUAD | 1 |
p.D13N | SKCM | 1 |
p.R9* | STAD | 1 |
p.S60C | LGG | 1 |
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TissGeneCNV for MAGEB16 |
Copy number variations of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of CNV samples) (TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16) |
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TissGeneFusions for MAGEB16 |
Fusion genes including TissGene (ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01) |
Database | Src | Cancer type | Sample | Fusion gene | ORF | 5'-gene BP | 3'-gene BP |
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TissGeneNet for MAGEB16 |
Co-expressed gene networks based on protein-protein interaction data (CePIN) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (PINA2 ppi data) |
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TissGeneProg for MAGEB16 |
Kaplan-Meier plots with logrank tests of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image to enlarge it in a new window. |
Kaplan-Meier plots with logrank test of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
Forest plot of Cox proportional hazard ratio (HR) and 95% CI of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
Forest plot of Cox proportional hazard ratio (HR) and 95% CI of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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TissGeneClin for MAGEB16 |
TissGeneDrug for MAGEB16 |
Drug information targeting TissGene (DrugBank Version 5.0.6, 2017-04-01) |
DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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TissGeneDisease for MAGEB16 |
Disease information associated with TissGene (DisGeNet, 2016-06-01) |
Disease ID | Disease name | # pubmeds | Source |