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TissGeneSummary for CD300LG |
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Basic gene information | Gene symbol | CD300LG |
Gene name | CD300 molecule-like family member g | |
Synonyms | CLM-9|CLM9|NEPMUCIN|TREM-4|TREM4 | |
Cytomap | UCSC genome browser: 17q21.31 | |
Type of gene | protein-coding | |
RefGenes | NM_001168322.1, NM_001168323.1,NM_001168324.1,NM_145273.3, | |
Description | CD300 antigen like family member GCD300 antigen-like family member GCD300 molecule like family member gCMRF35-like molecule 9triggering receptor expressed on myeloid cells 4 | |
Modification date | 20141207 | |
dbXrefs | MIM : 610520 | |
HGNC : HGNC | ||
Ensembl : ENSG00000161649 | ||
HPRD : 18222 | ||
Vega : OTTHUMG00000181796 | ||
Protein | UniProt: go to UniProt's Cross Reference DB Table | |
Expression | CleanEX: HS_CD300LG | |
BioGPS: 146894 | ||
Pathway | NCI Pathway Interaction Database: CD300LG | |
KEGG: CD300LG | ||
REACTOME: CD300LG | ||
Pathway Commons: CD300LG | ||
Context | iHOP: CD300LG | |
ligand binding site mutation search in PubMed: CD300LG | ||
UCL Cancer Institute: CD300LG | ||
Assigned class in TissGDB* | C | |
Included tissue-specific gene expression resources | ||
Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx) | BreastTestis | |
Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA) | BRCATGCT | |
Reference showing the relevant tissue of CD300LG | ||
Description by TissGene annotations |
* Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C. |
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GO ID | GO term | PubMed ID |
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TissGeneExp for CD300LG |
![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
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![]() (TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01) |
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![]() (GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct) - Here, we shows the matched tissue types only among our 28 cancer types. |
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![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
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- Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05) |
Cancer type | Mean(exp) in tumor | Mean(exp) in matched normal | Log2FC | P-val. | FDR |
LUSC | -1.028149883 | 5.182601097 | -6.21075098 | 7.35E-35 | 8.71E-33 |
PRAD | 0.204544423 | 1.888040577 | -1.683496154 | 4.72E-10 | 8.45E-09 |
COAD | -1.348626731 | 1.244111731 | -2.592738462 | 1.48E-06 | 8.03E-06 |
KIRP | 0.076569663 | 3.580360288 | -3.503790625 | 3.58E-14 | 7.95E-13 |
THCA | -0.324539182 | 1.976286242 | -2.300825424 | 8.79E-13 | 7.85E-12 |
LUAD | -0.440540789 | 5.263060935 | -5.703601724 | 1.03E-34 | 2.57E-32 |
KIRC | 1.478499872 | 3.634247094 | -2.155747222 | 4.57E-14 | 2.16E-13 |
BRCA | 1.262518951 | 7.473191758 | -6.210672807 | 1.05E-54 | 1.97E-52 |
KICH | 1.154238038 | 3.875222038 | -2.720984 | 4.21E-07 | 1.70E-06 |
BLCA | -1.72919333 | 2.516838249 | -4.246031579 | 4.88E-11 | 1.55E-08 |
STAD | -1.247567837 | 1.131863413 | -2.37943125 | 3.94E-08 | 1.34E-06 |
HNSC | -1.769343636 | 1.173605201 | -2.942948837 | 1.68E-14 | 1.02E-12 |
ESCA | -1.637309598 | 1.623254038 | -3.260563636 | 3.76E-05 | 0.001639655 |
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TissGene-miRNA for CD300LG |
![]() (Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016) (TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21) (TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16) (Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25)) |
Cancer type | miRNA id | miRNA accession | P-val. | Coeff. | # samples |
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TissGeneMut for CD300LG |
TissGeneSNV for CD300LG |
![]() Different colors of circles represent different cancer types. Circle size denotes number of samples. (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) * Click on the image to enlarge it in a new window. |
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![]() (X-axis: cancer type and Y-axis: % of mutated samples) The numbers in parentheses are numbers of samples with mutation (nsSNVs). (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) |
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- nsSNVs sorted by frequency. |
AAchange | Cancer type | # samples |
p.E299K | SKCM | 2 |
p.E110K | SKCM | 2 |
p.R47Q | LGG | 1 |
p.Y166N | LUSC | 1 |
p.E24K | SKCM | 1 |
p.P157L | READ | 1 |
p.Y190H | BRCA | 1 |
p.A150T | BLCA | 1 |
p.R146S | LUAD | 1 |
p.T98I | SKCM | 1 |
p.A152D | SARC | 1 |
p.E68D | STAD | 1 |
p.L119M | LUAD | 1 |
p.R47Q | STAD | 1 |
p.Q305* | BRCA | 1 |
p.E23Q | BLCA | 1 |
p.P148L | UCEC | 1 |
p.G143E | SKCM | 1 |
p.Y190* | LUSC | 1 |
p.V311L | HNSC | 1 |
p.P158L | LUAD | 1 |
p.R215C | LUAD | 1 |
p.K289N | UCEC | 1 |
p.P126S | SARC | 1 |
p.P303L | LUSC | 1 |
p.C37F | COAD | 1 |
p.E69* | UCEC | 1 |
p.P129S | SKCM | 1 |
p.Q280L | LUAD | 1 |
p.P185T | KIRC | 1 |
p.S26C | BLCA | 1 |
p.R247C | LIHC | 1 |
p.T319S | COAD | 1 |
p.P132S | SKCM | 1 |
p.E110K | LUAD | 1 |
p.E301K | SKCM | 1 |
p.C51R | OV | 1 |
p.S188F | SARC | 1 |
p.A306V | SKCM | 1 |
p.R294C | UCEC | 1 |
p.L184F | KIRC | 1 |
p.R112Q | LUAD | 1 |
p.P163S | SKCM | 1 |
p.R60H | KIRC | 1 |
p.P171T | COAD | 1 |
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TissGeneCNV for CD300LG |
![]() (TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16) |
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TissGeneFusions for CD300LG |
![]() (ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01) |
Database | Src | Cancer type | Sample | Fusion gene | ORF | 5'-gene BP | 3'-gene BP |
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TissGeneNet for CD300LG |
![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (PINA2 ppi data) |
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TissGeneProg for CD300LG |
![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image to enlarge it in a new window. |
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![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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![]() (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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TissGeneClin for CD300LG |
TissGeneDrug for CD300LG |
![]() (DrugBank Version 5.0.6, 2017-04-01) |
DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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TissGeneDisease for CD300LG |
![]() (DisGeNet, 2016-06-01) |
Disease ID | Disease name | # pubmeds | Source |
umls:C0020538 | Hypertensive disease | 1 | BeFree |