TissGeneSummary for FAM47A |
Gene summary |
Basic gene information | Gene symbol | FAM47A |
Gene name | family with sequence similarity 47, member A | |
Synonyms | - | |
Cytomap | UCSC genome browser: Xp21.1 | |
Type of gene | protein-coding | |
RefGenes | NM_203408.3, | |
Description | protein FAM47A | |
Modification date | 20141207 | |
dbXrefs | HGNC : HGNC | |
Ensembl : ENSG00000185448 | ||
HPRD : 10947 | ||
Vega : OTTHUMG00000021339 | ||
Protein | UniProt: go to UniProt's Cross Reference DB Table | |
Expression | CleanEX: HS_FAM47A | |
BioGPS: 158724 | ||
Pathway | NCI Pathway Interaction Database: FAM47A | |
KEGG: FAM47A | ||
REACTOME: FAM47A | ||
Pathway Commons: FAM47A | ||
Context | iHOP: FAM47A | |
ligand binding site mutation search in PubMed: FAM47A | ||
UCL Cancer Institute: FAM47A | ||
Assigned class in TissGDB* | C | |
Included tissue-specific gene expression resources | HPA,GTEx | |
Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx) | Testis | |
Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA) | TGCT | |
Reference showing the relevant tissue of FAM47A | ||
Description by TissGene annotations |
* Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C. |
Gene ontology having evidence of Inferred from Direct Assay (IDA) from Entrez |
GO ID | GO term | PubMed ID |
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TissGeneExp for FAM47A |
Gene expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
Gene isoform expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01) |
Gene expressions across normal tissues of GTEx data (GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct) - Here, we shows the matched tissue types only among our 28 cancer types. |
Different expressions across 14 cancer types with more than 10 samples between matched tumors and normals (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
- Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05) |
Cancer type | Mean(exp) in tumor | Mean(exp) in matched normal | Log2FC | P-val. | FDR |
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TissGene-miRNA for FAM47A |
Significantly anti-correlated miRNAs of TissGene across 28 cancer types (Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016) (TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21) (TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16) (Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25)) |
Cancer type | miRNA id | miRNA accession | P-val. | Coeff. | # samples |
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TissGeneMut for FAM47A |
TissGeneSNV for FAM47A |
nsSNV counts per each loci. Different colors of circles represent different cancer types. Circle size denotes number of samples. (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) * Click on the image to enlarge it in a new window. |
Somatic nucleotide variants of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of mutated samples) The numbers in parentheses are numbers of samples with mutation (nsSNVs). (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) |
- nsSNVs sorted by frequency. |
AAchange | Cancer type | # samples |
p.E378K | SKCM | 3 |
p.Y60C | LUAD | 2 |
p.R576Q | SKCM | 2 |
p.P713L | SKCM | 2 |
p.D3N | SKCM | 2 |
p.S105F | SKCM | 2 |
p.P573L | SKCM | 2 |
p.S519* | LUAD | 2 |
p.R361H | BLCA | 2 |
p.W705* | SKCM | 2 |
p.R544C | SKCM | 2 |
p.G372W | LUSC | 2 |
p.R518C | SKCM | 2 |
p.R487Q | READ | 1 |
p.V595I | CESC | 1 |
p.S685P | OV | 1 |
p.M776I | SKCM | 1 |
p.R255H | BLCA | 1 |
p.R72C | LUSC | 1 |
p.R345S | LUAD | 1 |
p.R37H | COAD | 1 |
p.T291R | LIHC | 1 |
p.E726K | SKCM | 1 |
p.T537N | UCEC | 1 |
p.K574N | UCS | 1 |
p.G747C | HNSC | 1 |
p.E307K | PAAD | 1 |
p.P317T | HNSC | 1 |
p.R314C | SKCM | 1 |
p.L337F | SKCM | 1 |
p.R412C | SKCM | 1 |
p.E307K | UCEC | 1 |
p.P109L | SKCM | 1 |
p.H246N | LUAD | 1 |
p.E507D | BRCA | 1 |
p.R73H | GBM | 1 |
p.R361H | PCPG | 1 |
p.D664N | SKCM | 1 |
p.R576Q | LGG | 1 |
p.K368N | LUAD | 1 |
p.H492Y | SKCM | 1 |
p.D268N | LUAD | 1 |
p.F58L | LUAD | 1 |
p.D268Y | LIHC | 1 |
p.E446Q | LGG | 1 |
p.R500Q | COAD | 1 |
p.R551H | LIHC | 1 |
p.G735V | PRAD | 1 |
p.K667T | READ | 1 |
p.C166F | LUAD | 1 |
p.D443N | SKCM | 1 |
p.T287A | UCEC | 1 |
p.G531D | UCEC | 1 |
p.V118I | COAD | 1 |
p.P192S | SKCM | 1 |
p.G619E | SKCM | 1 |
p.R602G | COAD | 1 |
p.E158K | SKCM | 1 |
p.P290A | LIHC | 1 |
p.H376R | LUSC | 1 |
p.H479Y | DLBC | 1 |
p.S476F | SKCM | 1 |
p.D732N | SKCM | 1 |
p.E571Q | LUAD | 1 |
p.V118I | GBM | 1 |
p.P252A | HNSC | 1 |
p.R448Q | HNSC | 1 |
p.Q755* | BLCA | 1 |
p.V729I | LUAD | 1 |
p.P63L | SKCM | 1 |
p.E390K | SKCM | 1 |
p.W698R | OV | 1 |
p.P179A | LUAD | 1 |
p.A88V | SKCM | 1 |
p.P391L | SKCM | 1 |
p.P483S | SKCM | 1 |
p.C188S | SKCM | 1 |
p.R224L | ACC | 1 |
p.K405E | LUAD | 1 |
p.P717S | SKCM | 1 |
p.A759S | LUAD | 1 |
p.R277Q | READ | 1 |
p.E289K | SKCM | 1 |
p.P183T | LUAD | 1 |
p.E378K | HNSC | 1 |
p.E66K | BRCA | 1 |
p.D275Y | LUAD | 1 |
p.M658I | LUAD | 1 |
p.E122K | SKCM | 1 |
p.E378* | UCEC | 1 |
p.E205K | SKCM | 1 |
p.P279L | SKCM | 1 |
p.A688S | LUAD | 1 |
p.S570L | SKCM | 1 |
p.I737V | LIHC | 1 |
p.L599F | LUAD | 1 |
p.P297S | SARC | 1 |
p.G282D | LUAD | 1 |
p.S685C | LUSC | 1 |
p.R338C | BRCA | 1 |
p.R690L | LUAD | 1 |
p.P237Q | LUAD | 1 |
p.P42L | SKCM | 1 |
p.W698* | HNSC | 1 |
p.E672K | SKCM | 1 |
p.Q420L | LUAD | 1 |
p.R370C | UCEC | 1 |
p.P130S | SKCM | 1 |
p.P213T | ESCA | 1 |
p.P462S | HNSC | 1 |
p.E622K | SKCM | 1 |
p.P249Q | HNSC | 1 |
p.P462L | HNSC | 1 |
p.R314H | ESCA | 1 |
p.R255C | HNSC | 1 |
p.G333E | SKCM | 1 |
p.L77F | HNSC | 1 |
p.S570L | HNSC | 1 |
p.R609C | UCEC | 1 |
p.A88P | STAD | 1 |
p.P330T | GBM | 1 |
p.V595A | LIHC | 1 |
p.E465K | HNSC | 1 |
p.K549N | LUAD | 1 |
p.G735E | SKCM | 1 |
p.P109S | SKCM | 1 |
p.G180C | HNSC | 1 |
p.P130L | SKCM | 1 |
p.P480T | LUAD | 1 |
p.Q111L | LUAD | 1 |
p.C298* | PRAD | 1 |
p.R576Q | LUSC | 1 |
p.S685Y | UCEC | 1 |
p.V729I | THCA | 1 |
p.P179H | LUAD | 1 |
p.A31V | PRAD | 1 |
p.R412H | UCEC | 1 |
p.P79S | SKCM | 1 |
p.S519P | SARC | 1 |
p.R371L | LUAD | 1 |
p.K106T | LUAD | 1 |
p.R412C | UCEC | 1 |
p.R518H | STAD | 1 |
p.E649* | LUSC | 1 |
p.E193K | LGG | 1 |
p.G616A | LUAD | 1 |
p.L730I | UCEC | 1 |
p.E582* | UCEC | 1 |
p.R37H | STAD | 1 |
p.P713S | SKCM | 1 |
p.A278D | LUAD | 1 |
p.H567N | LUAD | 1 |
p.T501M | COAD | 1 |
p.P225R | LUAD | 1 |
p.R500W | OV | 1 |
p.D728N | UCEC | 1 |
p.V51M | SKCM | 1 |
p.F76I | STAD | 1 |
p.K746N | LUAD | 1 |
p.E292V | LUAD | 1 |
p.S683L | UCEC | 1 |
p.F569L | UCEC | 1 |
p.E160D | UCEC | 1 |
p.E75K | SKCM | 1 |
p.E665V | LIHC | 1 |
p.P79L | LGG | 1 |
p.R539* | UCEC | 1 |
p.K746* | LUSC | 1 |
p.D144Y | HNSC | 1 |
p.A365V | UCEC | 1 |
p.E75K | UCEC | 1 |
p.E292* | LUAD | 1 |
p.L337V | LUAD | 1 |
p.R72H | HNSC | 1 |
p.D57N | LUAD | 1 |
p.R774C | STAD | 1 |
p.T230S | UCEC | 1 |
p.R448W | LGG | 1 |
p.P366T | LUAD | 1 |
p.H336N | LUAD | 1 |
p.R544G | BLCA | 1 |
p.P290L | SKCM | 1 |
p.G407A | HNSC | 1 |
p.G735R | SKCM | 1 |
p.E649K | SKCM | 1 |
p.S434P | BRCA | 1 |
p.Q46H | LUAD | 1 |
p.R361H | HNSC | 1 |
p.P713T | OV | 1 |
p.R371Q | SKCM | 1 |
p.E533D | STAD | 1 |
p.E472K | SKCM | 1 |
p.E593* | HNSC | 1 |
p.C188F | LUAD | 1 |
p.K643N | STAD | 1 |
p.L375P | LUAD | 1 |
p.R539Q | LGG | 1 |
p.P401T | LUAD | 1 |
p.P192L | SKCM | 1 |
p.A563T | LUSC | 1 |
p.R326C | HNSC | 1 |
p.F76I | PRAD | 1 |
p.H198P | LIHC | 1 |
p.R538C | UCEC | 1 |
p.K607E | UVM | 1 |
p.P633H | LUAD | 1 |
p.L387R | READ | 1 |
p.E559K | CESC | 1 |
p.V118I | KIRC | 1 |
p.E356K | LUSC | 1 |
p.K663T | STAD | 1 |
p.R371W | STAD | 1 |
p.F631L | SKCM | 1 |
p.A116T | SKCM | 1 |
p.R487Q | PAAD | 1 |
p.R760K | LGG | 1 |
p.S245C | ESCA | 1 |
p.S269F | SKCM | 1 |
p.T194A | LIHC | 1 |
p.R72H | OV | 1 |
p.H557Y | SKCM | 1 |
p.P219L | LUAD | 1 |
p.S590R | STAD | 1 |
p.P354S | SKCM | 1 |
p.R351H | LIHC | 1 |
p.P213Q | SKCM | 1 |
p.R345C | SKCM | 1 |
p.Q755* | LUAD | 1 |
p.K746N | HNSC | 1 |
p.E726G | LUAD | 1 |
p.G372W | HNSC | 1 |
p.P532L | UCEC | 1 |
p.H567Q | BRCA | 1 |
p.D641N | SKCM | 1 |
p.T537I | SKCM | 1 |
p.E786* | LUAD | 1 |
p.C298X | PRAD | 1 |
p.F668L | UCEC | 1 |
p.R59C | LUAD | 1 |
p.R544L | LUAD | 1 |
p.S92N | UCEC | 1 |
p.S419R | HNSC | 1 |
p.R326C | COAD | 1 |
p.P201S | BLCA | 1 |
p.R609H | SARC | 1 |
p.P176H | LUAD | 1 |
p.R224H | ESCA | 1 |
p.C445S | LIHC | 1 |
p.R518G | CESC | 1 |
p.S490G | HNSC | 1 |
p.A759G | LUAD | 1 |
p.S461F | SKCM | 1 |
p.R690H | LUAD | 1 |
p.E481K | SKCM | 1 |
p.R486L | LUSC | 1 |
p.P558L | STAD | 1 |
p.N627I | LUSC | 1 |
p.T218P | HNSC | 1 |
p.V595I | SKCM | 1 |
p.W163C | LIHC | 1 |
p.E593V | LUAD | 1 |
p.R59H | HNSC | 1 |
p.R505H | UCEC | 1 |
p.R73L | LUAD | 1 |
p.P219L | STAD | 1 |
p.R283W | STAD | 1 |
p.E571* | LUSC | 1 |
p.R346Q | COAD | 1 |
p.R283W | LGG | 1 |
p.P471T | LUAD | 1 |
p.E66K | GBM | 1 |
p.T177N | HNSC | 1 |
p.Q671* | LUAD | 1 |
p.P219L | SKCM | 1 |
p.H234Y | LIHC | 1 |
p.L150R | COAD | 1 |
p.R72L | LUAD | 1 |
p.R248G | LUAD | 1 |
p.P195L | SKCM | 1 |
p.P534L | ESCA | 1 |
p.R436T | LUAD | 1 |
p.E284K | THYM | 1 |
p.A365V | PRAD | 1 |
p.E586K | SKCM | 1 |
p.R487Q | KIRP | 1 |
p.P155S | SKCM | 1 |
p.S108F | LAML | 1 |
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TissGeneCNV for FAM47A |
Copy number variations of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of CNV samples) (TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16) |
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TissGeneFusions for FAM47A |
Fusion genes including TissGene (ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01) |
Database | Src | Cancer type | Sample | Fusion gene | ORF | 5'-gene BP | 3'-gene BP |
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TissGeneNet for FAM47A |
Co-expressed gene networks based on protein-protein interaction data (CePIN) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (PINA2 ppi data) |
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TissGeneProg for FAM47A |
Kaplan-Meier plots with logrank tests of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image to enlarge it in a new window. |
Kaplan-Meier plots with logrank test of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
Forest plot of Cox proportional hazard ratio (HR) and 95% CI of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
Forest plot of Cox proportional hazard ratio (HR) and 95% CI of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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TissGeneClin for FAM47A |
TissGeneDrug for FAM47A |
Drug information targeting TissGene (DrugBank Version 5.0.6, 2017-04-01) |
DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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TissGeneDisease for FAM47A |
Disease information associated with TissGene (DisGeNet, 2016-06-01) |
Disease ID | Disease name | # pubmeds | Source |