TissGeneSummary for FNDC7 |
Gene summary |
Basic gene information | Gene symbol | FNDC7 |
Gene name | fibronectin type III domain containing 7 | |
Synonyms | - | |
Cytomap | UCSC genome browser: 1p13.3 | |
Type of gene | protein-coding | |
RefGenes | NM_001144937.1, NM_173532.1, | |
Description | fibronectin type III domain-containing protein 7 | |
Modification date | 20141207 | |
dbXrefs | HGNC : HGNC | |
Ensembl : ENSG00000143107 | ||
HPRD : 08195 | ||
Vega : OTTHUMG00000011120 | ||
Protein | UniProt: go to UniProt's Cross Reference DB Table | |
Expression | CleanEX: HS_FNDC7 | |
BioGPS: 163479 | ||
Pathway | NCI Pathway Interaction Database: FNDC7 | |
KEGG: FNDC7 | ||
REACTOME: FNDC7 | ||
Pathway Commons: FNDC7 | ||
Context | iHOP: FNDC7 | |
ligand binding site mutation search in PubMed: FNDC7 | ||
UCL Cancer Institute: FNDC7 | ||
Assigned class in TissGDB* | C | |
Included tissue-specific gene expression resources | HPA,GTEx | |
Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx) | Testis | |
Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA) | TGCT | |
Reference showing the relevant tissue of FNDC7 | ||
Description by TissGene annotations |
* Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C. |
Gene ontology having evidence of Inferred from Direct Assay (IDA) from Entrez |
GO ID | GO term | PubMed ID |
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TissGeneExp for FNDC7 |
Gene expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
Gene isoform expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01) |
Gene expressions across normal tissues of GTEx data (GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct) - Here, we shows the matched tissue types only among our 28 cancer types. |
Different expressions across 14 cancer types with more than 10 samples between matched tumors and normals (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
- Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05) |
Cancer type | Mean(exp) in tumor | Mean(exp) in matched normal | Log2FC | P-val. | FDR |
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TissGene-miRNA for FNDC7 |
Significantly anti-correlated miRNAs of TissGene across 28 cancer types (Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016) (TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21) (TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16) (Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25)) |
Cancer type | miRNA id | miRNA accession | P-val. | Coeff. | # samples |
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TissGeneMut for FNDC7 |
TissGeneSNV for FNDC7 |
nsSNV counts per each loci. Different colors of circles represent different cancer types. Circle size denotes number of samples. (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) * Click on the image to enlarge it in a new window. |
Somatic nucleotide variants of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of mutated samples) The numbers in parentheses are numbers of samples with mutation (nsSNVs). (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) |
- nsSNVs sorted by frequency. |
AAchange | Cancer type | # samples |
p.R510W | UCEC | 2 |
p.P372L | SKCM | 2 |
p.E525K | SKCM | 2 |
p.S717Y | UCEC | 1 |
p.S265L | BLCA | 1 |
p.A205S | THYM | 1 |
p.N560K | DLBC | 1 |
p.W307R | THYM | 1 |
p.S376T | LUAD | 1 |
p.D271N | LUAD | 1 |
p.V542L | STAD | 1 |
p.A317V | BRCA | 1 |
p.G496E | LUAD | 1 |
p.R224L | LUAD | 1 |
p.H329L | BLCA | 1 |
p.F348V | THCA | 1 |
p.L497V | LUAD | 1 |
p.R638S | THYM | 1 |
p.G595R | SKCM | 1 |
p.M411I | SKCM | 1 |
p.E733K | CESC | 1 |
p.G65W | LIHC | 1 |
p.G640D | STAD | 1 |
p.P533H | LUAD | 1 |
p.E399K | SKCM | 1 |
p.S448L | SKCM | 1 |
p.D416N | LIHC | 1 |
p.R510W | STAD | 1 |
p.W222C | LUAD | 1 |
p.P708L | SKCM | 1 |
p.L382F | PCPG | 1 |
p.E399K | READ | 1 |
p.I146S | LIHC | 1 |
p.Q589X | SKCM | 1 |
p.R5L | THYM | 1 |
p.D469N | SKCM | 1 |
p.N560K | BRCA | 1 |
p.A205T | ESCA | 1 |
p.M234T | LIHC | 1 |
p.P513S | UCEC | 1 |
p.P631L | SKCM | 1 |
p.V542_splice | LUSC | 1 |
p.Q499* | BLCA | 1 |
p.S696L | CESC | 1 |
p.G728R | SKCM | 1 |
p.Y637H | SKCM | 1 |
p.A420V | UCEC | 1 |
p.I15S | UCEC | 1 |
p.T669M | STAD | 1 |
p.P631S | SKCM | 1 |
p.A405T | SKCM | 1 |
p.V293A | BLCA | 1 |
p.S611I | THYM | 1 |
p.R292I | UCEC | 1 |
p.D323N | SKCM | 1 |
p.E505Q | BLCA | 1 |
p.Q209K | CESC | 1 |
p.E733X | COAD | 1 |
p.L236F | LUSC | 1 |
p.S76F | UCEC | 1 |
p.V724M | KIRC | 1 |
p.G259R | SKCM | 1 |
p.Q589* | SKCM | 1 |
p.T508I | SKCM | 1 |
p.A470V | PRAD | 1 |
p.P361S | BRCA | 1 |
p.G325V | THYM | 1 |
p.F345L | BLCA | 1 |
p.C374R | HNSC | 1 |
p.L593F | LIHC | 1 |
p.T488M | BRCA | 1 |
p.Y262H | SKCM | 1 |
p.S695L | BLCA | 1 |
p.E402K | SKCM | 1 |
p.S448P | STAD | 1 |
p.P543S | UCEC | 1 |
p.E399* | LUAD | 1 |
p.E261D | SKCM | 1 |
p.S193F | SARC | 1 |
p.R224L | SKCM | 1 |
p.T613N | ESCA | 1 |
p.M473I | SKCM | 1 |
p.S279L | DLBC | 1 |
p.R638M | LUAD | 1 |
p.G65R | COAD | 1 |
p.P451S | LUAD | 1 |
p.G687E | STAD | 1 |
p.N230I | STAD | 1 |
p.Y603C | STAD | 1 |
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TissGeneCNV for FNDC7 |
Copy number variations of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of CNV samples) (TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16) |
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TissGeneFusions for FNDC7 |
Fusion genes including TissGene (ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01) |
Database | Src | Cancer type | Sample | Fusion gene | ORF | 5'-gene BP | 3'-gene BP |
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TissGeneNet for FNDC7 |
Co-expressed gene networks based on protein-protein interaction data (CePIN) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (PINA2 ppi data) |
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TissGeneProg for FNDC7 |
Kaplan-Meier plots with logrank tests of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image to enlarge it in a new window. |
Kaplan-Meier plots with logrank test of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
Forest plot of Cox proportional hazard ratio (HR) and 95% CI of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
Forest plot of Cox proportional hazard ratio (HR) and 95% CI of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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TissGeneClin for FNDC7 |
TissGeneDrug for FNDC7 |
Drug information targeting TissGene (DrugBank Version 5.0.6, 2017-04-01) |
DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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TissGeneDisease for FNDC7 |
Disease information associated with TissGene (DisGeNet, 2016-06-01) |
Disease ID | Disease name | # pubmeds | Source |