TissGeneSummary for ZNF679 |
Gene summary |
Basic gene information | Gene symbol | ZNF679 |
Gene name | zinc finger protein 679 | |
Synonyms | - | |
Cytomap | UCSC genome browser: 7q11.21 | |
Type of gene | protein-coding | |
RefGenes | NM_153363.2, | |
Description | hypothetical protein MGC42415 | |
Modification date | 20141207 | |
dbXrefs | HGNC : HGNC | |
Ensembl : ENSG00000197123 | ||
HPRD : 14621 | ||
Vega : OTTHUMG00000156486 | ||
Protein | UniProt: go to UniProt's Cross Reference DB Table | |
Expression | CleanEX: HS_ZNF679 | |
BioGPS: 168417 | ||
Pathway | NCI Pathway Interaction Database: ZNF679 | |
KEGG: ZNF679 | ||
REACTOME: ZNF679 | ||
Pathway Commons: ZNF679 | ||
Context | iHOP: ZNF679 | |
ligand binding site mutation search in PubMed: ZNF679 | ||
UCL Cancer Institute: ZNF679 | ||
Assigned class in TissGDB* | C | |
Included tissue-specific gene expression resources | HPA,GTEx | |
Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx) | Testis | |
Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA) | TGCT | |
Reference showing the relevant tissue of ZNF679 | ||
Description by TissGene annotations |
* Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C. |
Gene ontology having evidence of Inferred from Direct Assay (IDA) from Entrez |
GO ID | GO term | PubMed ID |
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TissGeneExp for ZNF679 |
Gene expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
Gene isoform expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01) |
Gene expressions across normal tissues of GTEx data (GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct) - Here, we shows the matched tissue types only among our 28 cancer types. |
Different expressions across 14 cancer types with more than 10 samples between matched tumors and normals (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
- Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05) |
Cancer type | Mean(exp) in tumor | Mean(exp) in matched normal | Log2FC | P-val. | FDR |
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TissGene-miRNA for ZNF679 |
Significantly anti-correlated miRNAs of TissGene across 28 cancer types (Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016) (TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21) (TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16) (Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25)) |
Cancer type | miRNA id | miRNA accession | P-val. | Coeff. | # samples |
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TissGeneMut for ZNF679 |
TissGeneSNV for ZNF679 |
nsSNV counts per each loci. Different colors of circles represent different cancer types. Circle size denotes number of samples. (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) * Click on the image to enlarge it in a new window. |
Somatic nucleotide variants of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of mutated samples) The numbers in parentheses are numbers of samples with mutation (nsSNVs). (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) |
- nsSNVs sorted by frequency. |
AAchange | Cancer type | # samples |
p.H262Y | SKCM | 3 |
p.F25L | UCEC | 2 |
p.R260K | UCEC | 2 |
p.R11Q | SKCM | 2 |
p.F363L | UCEC | 2 |
p.S26F | SKCM | 2 |
p.H35Y | SKCM | 2 |
p.Y352F | COAD | 1 |
p.R19K | SKCM | 1 |
p.S130I | UCEC | 1 |
p.S400I | UCEC | 1 |
p.L33Q | LUAD | 1 |
p.R11* | PRAD | 1 |
p.E299K | SKCM | 1 |
p.E378V | SKCM | 1 |
p.R316I | COAD | 1 |
p.S169L | SKCM | 1 |
p.N51D | HNSC | 1 |
p.E209K | SKCM | 1 |
p.G404V | SKCM | 1 |
p.E12Q | BLCA | 1 |
p.S306N | SKCM | 1 |
p.L123I | KIRC | 1 |
p.T176K | ESCA | 1 |
p.E216D | PRAD | 1 |
p.Y212* | LUAD | 1 |
p.E24K | SKCM | 1 |
p.E300K | SKCM | 1 |
p.H370Y | SKCM | 1 |
p.L64M | BLCA | 1 |
p.K167N | COAD | 1 |
p.D34N | SKCM | 1 |
p.C186R | BRCA | 1 |
p.C354F | LUAD | 1 |
p.Q203K | LUAD | 1 |
p.R316I | UCEC | 1 |
p.V83L | LUAD | 1 |
p.K72E | UCEC | 1 |
p.Y240C | STAD | 1 |
p.E143D | LIHC | 1 |
p.S253L | BLCA | 1 |
p.E28* | LUAD | 1 |
p.F249Y | SKCM | 1 |
p.Q275K | LUAD | 1 |
p.R42I | LUAD | 1 |
p.E73K | KIRP | 1 |
p.D121E | CESC | 1 |
p.R173K | SKCM | 1 |
p.Q157* | SKCM | 1 |
p.G292V | LUAD | 1 |
p.H262N | LUAD | 1 |
p.R11Q | LGG | 1 |
p.S118R | STAD | 1 |
p.K117Q | SKCM | 1 |
p.T84I | SKCM | 1 |
p.S211F | SKCM | 1 |
p.S252F | LUAD | 1 |
p.D121G | COAD | 1 |
p.E237Q | LUAD | 1 |
p.K343N | COAD | 1 |
p.R79I | SKCM | 1 |
p.S400N | DLBC | 1 |
p.P239T | LUAD | 1 |
p.A58V | SKCM | 1 |
p.T375N | UCEC | 1 |
p.C298F | LUAD | 1 |
p.T366N | UCEC | 1 |
p.A58V | HNSC | 1 |
p.C67Y | PRAD | 1 |
p.L107V | LGG | 1 |
p.S10T | BRCA | 1 |
p.Q37H | PAAD | 1 |
p.Q203* | CESC | 1 |
p.G246D | PRAD | 1 |
p.H234Y | SKCM | 1 |
p.T291I | SKCM | 1 |
p.H206D | HNSC | 1 |
p.A2S | ESCA | 1 |
p.C410F | ESCA | 1 |
p.S54F | SKCM | 1 |
p.L64M | SKCM | 1 |
p.E73X | ESCA | 1 |
p.E143K | SKCM | 1 |
p.E209X | THYM | 1 |
p.E300* | HNSC | 1 |
p.E81D | UCEC | 1 |
p.H86Y | BLCA | 1 |
p.M401L | DLBC | 1 |
p.S130I | COAD | 1 |
p.K315N | SKCM | 1 |
p.L27Q | LIHC | 1 |
p.S278I | THYM | 1 |
p.K229E | SKCM | 1 |
p.E328K | TGCT | 1 |
p.H346Y | SKCM | 1 |
p.R42T | LUAD | 1 |
p.C223S | LIHC | 1 |
p.P323R | KIRP | 1 |
p.K188T | UCEC | 1 |
p.T17K | KIRP | 1 |
p.S169L | HNSC | 1 |
p.E73* | ESCA | 1 |
p.A360D | PAAD | 1 |
p.P220S | SARC | 1 |
p.P98L | COAD | 1 |
p.G139V | LUAD | 1 |
p.S130R | UCEC | 1 |
p.K355E | THCA | 1 |
p.E29K | SKCM | 1 |
p.S310F | SKCM | 1 |
p.R113I | COAD | 1 |
p.K181N | LUAD | 1 |
p.C273Y | MESO | 1 |
p.K78N | LUAD | 1 |
p.C385Y | LIHC | 1 |
p.P295S | UCEC | 1 |
p.D386N | HNSC | 1 |
p.F184C | LIHC | 1 |
p.G264R | SKCM | 1 |
p.T263A | LUAD | 1 |
p.E47Q | LUAD | 1 |
p.W75* | SKCM | 1 |
p.Y212H | ACC | 1 |
p.E356V | SKCM | 1 |
p.G190D | SKCM | 1 |
p.E47D | UCEC | 1 |
p.E328K | ACC | 1 |
p.R288I | UCEC | 1 |
p.R113K | SKCM | 1 |
p.D20Y | OV | 1 |
p.K343N | LUAD | 1 |
p.K61N | PRAD | 1 |
p.S118C | LIHC | 1 |
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TissGeneCNV for ZNF679 |
Copy number variations of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of CNV samples) (TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16) |
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TissGeneFusions for ZNF679 |
Fusion genes including TissGene (ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01) |
Database | Src | Cancer type | Sample | Fusion gene | ORF | 5'-gene BP | 3'-gene BP |
Chimerdb3.0 | FusionScan | LUAD | TCGA-05-4402-01A | ZNF679-VOPP1 | In-Frame | chr7:63709534 | chr7:55588823 |
TCGAfusionPortal | PRADA | LUAD | TCGA-05-4402-01A | ZNF679-VOPP1 | In-frame | Chr7:63709534 | Chr7:55588823 |
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TissGeneNet for ZNF679 |
Co-expressed gene networks based on protein-protein interaction data (CePIN) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (PINA2 ppi data) |
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TissGeneProg for ZNF679 |
Kaplan-Meier plots with logrank tests of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image to enlarge it in a new window. |
Kaplan-Meier plots with logrank test of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
Forest plot of Cox proportional hazard ratio (HR) and 95% CI of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
Forest plot of Cox proportional hazard ratio (HR) and 95% CI of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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TissGeneClin for ZNF679 |
TissGeneDrug for ZNF679 |
Drug information targeting TissGene (DrugBank Version 5.0.6, 2017-04-01) |
DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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TissGeneDisease for ZNF679 |
Disease information associated with TissGene (DisGeNet, 2016-06-01) |
Disease ID | Disease name | # pubmeds | Source |
umls:C0040336 | Tobacco Use Disorder | 1 | GAD |