TissGDB

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	TissGeneSummary
	TissGeneExp
	TissGene-miRNA
	TissGeneMut: TissGeneSNV, TissGeneCNV, and TissGeneFusions
	TissGeneNet
	TissGeneProg
	TissGeneClin: TissGeneDrug and TissGeneDisease

TissGeneSummary for AFP

Gene summary

Basic gene information	Gene symbol	AFP
	Gene name	alpha-fetoprotein
	Synonyms	AFPD\|FETA\|HPAFP
	Cytomap	UCSC genome browser: 4q13.3
	Type of gene	protein-coding
	RefGenes	NM_001134.2,
	Description	alpha-1-fetoproteinalpha-fetoglobulin
	Modification date	20141222
dbXrefs	MIM : 104150
	HGNC : HGNC
	Ensembl : ENSG00000081051
	HPRD : 00074
	Vega : OTTHUMG00000130011
Protein	UniProt: go to UniProt's Cross Reference DB Table
Expression	CleanEX: HS_AFP
	BioGPS: 174
Pathway	NCI Pathway Interaction Database: AFP
	KEGG: AFP
	REACTOME: AFP
	Pathway Commons: AFP
Context	iHOP: AFP
	ligand binding site mutation search in PubMed: AFP
	UCL Cancer Institute: AFP
Assigned class in TissGDB*	C
Included tissue-specific gene expression resources	TiGER,GTEx
Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx)	Liver
Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA)	LIHC
Reference showing the relevant tissue of AFP
Description by TissGene annotations

* Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C.

Gene ontology having evidence of Inferred from Direct Assay (IDA) from Entrez

GO ID

GO term

PubMed ID

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TissGeneExp for AFP

Gene expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1))
(TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16)

Gene isoform expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1))
(TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01)

Gene expressions across normal tissues of GTEx data
(GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct)
- Here, we shows the matched tissue types only among our 28 cancer types.

Different expressions across 14 cancer types with more than 10 samples between matched tumors and normals (X-axis: cancer type and Y-axis: log2(norm_counts+1))
(TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16)

- Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05)

Cancer type	Mean(exp) in tumor	Mean(exp) in matched normal	Log2FC	P-val.	FDR
KICH	-2.459340643	0.412691357	-2.872032	2.80E-06	9.75E-06
KIRC	-0.958089921	0.823519801	-1.781609722	2.85E-06	7.03E-06
BRCA	-0.692872011	2.094725357	-2.787597368	3.45E-15	1.81E-14
KIRP	-0.848568393	1.215872232	-2.064440625	3.26E-05	0.00012409

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TissGene-miRNA for AFP

Significantly anti-correlated miRNAs of TissGene across 28 cancer types
(Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016)
(TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21)
(TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16)
(Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25))

Cancer type

miRNA id

miRNA accession

P-val.

Coeff.

# samples

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TissGeneMut for AFP

TissGeneSNV for AFP

nsSNV counts per each loci.
Different colors of circles represent different cancer types. Circle size denotes number of samples.
(TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25)
* Click on the image to enlarge it in a new window.

Somatic nucleotide variants of TissGene across 28 cancer types
(X-axis: cancer type and Y-axis: % of mutated samples)
The numbers in parentheses are numbers of samples with mutation (nsSNVs).
(TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25)

- nsSNVs sorted by frequency.

AAchange	Cancer type	# samples
p.D338N	SKCM	2
p.M227I	SKCM	2
p.R184C	SKCM	1
p.L275P	STAD	1
p.S34Y	UCEC	1
p.C583S	BRCA	1
p.A182V	STAD	1
p.Q420H	COAD	1
p.R121I	LGG	1
p.F354C	UCEC	1
p.R233*	UCEC	1
p.P323L	SKCM	1
p.G272*	PAAD	1
p.Q221*	SKCM	1
p.T241N	LUSC	1
p.K65I	SKCM	1
p.G608V	BLCA	1
p.D395N	LUAD	1
p.L330Q	LUAD	1
p.R184H	LUAD	1
p.I104M	UCEC	1
p.S6L	LUSC	1
p.D529N	BLCA	1
p.E119Q	BLCA	1
p.L371I	UCEC	1
p.E17K	SKCM	1
p.E165K	BLCA	1
p.S135L	COAD	1
p.H22Y	UCEC	1
p.S18C	LUSC	1
p.L87F	LUAD	1
p.G585S	SKCM	1
p.K242R	UCEC	1
p.G585D	SKCM	1
p.A544V	COAD	1
p.E346K	SKCM	1
p.M285I	UCEC	1
p.E595Q	CESC	1
p.A476V	COAD	1
p.Q140E	LUSC	1
p.E474K	KIRP	1
p.S327F	SKCM	1
p.S368P	UCS	1
p.W181*	LUAD	1
p.R332K	ACC	1
p.E399K	LUAD	1
p.V265L	GBM	1
p.S216I	UCEC	1
p.P495L	BLCA	1
p.Q221X	SKCM	1
p.Q378X	SKCM	1
p.A471T	SKCM	1
p.D528V	LUAD	1
p.K298I	SKCM	1
p.K246N	BLCA	1
p.K249R	UCEC	1
p.L180I	UCEC	1
p.E57Q	LIHC	1
p.E489G	UCEC	1
p.M448I	LUSC	1
p.T615I	ESCA	1
p.F531L	UCEC	1
p.Q341R	LUAD	1
p.H100N	LUAD	1
p.S84L	CESC	1
p.Q378*	SKCM	1
p.Q541X	SKCM	1
p.F526L	UCEC	1
p.N123T	UCEC	1
p.E489K	LUSC	1
p.K322T	UCEC	1
p.G272X	PAAD	1
p.E388K	SKCM	1
p.C224Y	UCEC	1
p.K76N	LGG	1
p.A449V	LGG	1
p.A195V	SKCM	1
p.R23I	COAD	1
p.E106D	LUAD	1
p.Q541*	SKCM	1
p.F342L	LGG	1
p.L553H	THYM	1
p.P363L	SKCM	1
p.R233Q	SKCM	1
p.A182G	LUAD	1
p.Q312H	CESC	1

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TissGeneCNV for AFP

Copy number variations of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of CNV samples)
(TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16)

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TissGeneFusions for AFP

Fusion genes including TissGene
(ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01)

Database	Src	Cancer type	Sample	Fusion gene	ORF	5'-gene BP	3'-gene BP
Chimerdb3.0	ChiTaRs	NA	BP238936	AFP-SORT1		chr4:74315824	chr1:109855081

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TissGeneNet for AFP

Co-expressed gene networks based on protein-protein interaction data (CePIN)
(TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16)
(PINA2 ppi data)

BRCA (tumor)	BRCA (normal)
AFP, HMGB1, NR3C1, CASP3, HLA-B, PSMB7, ING1, XIAP, SGSM2, GNB1, PHB2, STAMBP, MED27, CCR5, ZFHX3, EHD4, AP4S1, NKX2-8 (tumor)	AFP, HMGB1, NR3C1, CASP3, HLA-B, PSMB7, ING1, XIAP, SGSM2, GNB1, PHB2, STAMBP, MED27, CCR5, ZFHX3, EHD4, AP4S1, NKX2-8 (normal)

COAD (tumor)	COAD (normal)
AFP, HMGB1, NR3C1, CASP3, HLA-B, PSMB7, ING1, XIAP, SGSM2, GNB1, PHB2, STAMBP, MED27, CCR5, ZFHX3, EHD4, AP4S1, NKX2-8 (tumor)	AFP, HMGB1, NR3C1, CASP3, HLA-B, PSMB7, ING1, XIAP, SGSM2, GNB1, PHB2, STAMBP, MED27, CCR5, ZFHX3, EHD4, AP4S1, NKX2-8 (normal)

HNSC (tumor)	HNSC (normal)
AFP, HMGB1, NR3C1, CASP3, HLA-B, PSMB7, ING1, XIAP, SGSM2, GNB1, PHB2, STAMBP, MED27, CCR5, ZFHX3, EHD4, AP4S1, NKX2-8 (tumor)	AFP, HMGB1, NR3C1, CASP3, HLA-B, PSMB7, ING1, XIAP, SGSM2, GNB1, PHB2, STAMBP, MED27, CCR5, ZFHX3, EHD4, AP4S1, NKX2-8 (normal)

KICH (tumor)	KICH (normal)
AFP, HMGB1, NR3C1, CASP3, HLA-B, PSMB7, ING1, XIAP, SGSM2, GNB1, PHB2, STAMBP, MED27, CCR5, ZFHX3, EHD4, AP4S1, NKX2-8 (tumor)	AFP, HMGB1, NR3C1, CASP3, HLA-B, PSMB7, ING1, XIAP, SGSM2, GNB1, PHB2, STAMBP, MED27, CCR5, ZFHX3, EHD4, AP4S1, NKX2-8 (normal)

KIRC (tumor)	KIRC (normal)
AFP, HMGB1, NR3C1, CASP3, HLA-B, PSMB7, ING1, XIAP, SGSM2, GNB1, PHB2, STAMBP, MED27, CCR5, ZFHX3, EHD4, AP4S1, NKX2-8 (tumor)	AFP, HMGB1, NR3C1, CASP3, HLA-B, PSMB7, ING1, XIAP, SGSM2, GNB1, PHB2, STAMBP, MED27, CCR5, ZFHX3, EHD4, AP4S1, NKX2-8 (normal)

KIRP (tumor)	KIRP (normal)
AFP, HMGB1, NR3C1, CASP3, HLA-B, PSMB7, ING1, XIAP, SGSM2, GNB1, PHB2, STAMBP, MED27, CCR5, ZFHX3, EHD4, AP4S1, NKX2-8 (tumor)	AFP, HMGB1, NR3C1, CASP3, HLA-B, PSMB7, ING1, XIAP, SGSM2, GNB1, PHB2, STAMBP, MED27, CCR5, ZFHX3, EHD4, AP4S1, NKX2-8 (normal)

LIHC (tumor)	LIHC (normal)
AFP, HMGB1, NR3C1, CASP3, HLA-B, PSMB7, ING1, XIAP, SGSM2, GNB1, PHB2, STAMBP, MED27, CCR5, ZFHX3, EHD4, AP4S1, NKX2-8 (tumor)	AFP, HMGB1, NR3C1, CASP3, HLA-B, PSMB7, ING1, XIAP, SGSM2, GNB1, PHB2, STAMBP, MED27, CCR5, ZFHX3, EHD4, AP4S1, NKX2-8 (normal)

LUAD (tumor)	LUAD (normal)
AFP, HMGB1, NR3C1, CASP3, HLA-B, PSMB7, ING1, XIAP, SGSM2, GNB1, PHB2, STAMBP, MED27, CCR5, ZFHX3, EHD4, AP4S1, NKX2-8 (tumor)	AFP, HMGB1, NR3C1, CASP3, HLA-B, PSMB7, ING1, XIAP, SGSM2, GNB1, PHB2, STAMBP, MED27, CCR5, ZFHX3, EHD4, AP4S1, NKX2-8 (normal)

LUSC (tumor)	LUSC (normal)
AFP, HMGB1, NR3C1, CASP3, HLA-B, PSMB7, ING1, XIAP, SGSM2, GNB1, PHB2, STAMBP, MED27, CCR5, ZFHX3, EHD4, AP4S1, NKX2-8 (tumor)	AFP, HMGB1, NR3C1, CASP3, HLA-B, PSMB7, ING1, XIAP, SGSM2, GNB1, PHB2, STAMBP, MED27, CCR5, ZFHX3, EHD4, AP4S1, NKX2-8 (normal)

PRAD (tumor)	PRAD (normal)
AFP, HMGB1, NR3C1, CASP3, HLA-B, PSMB7, ING1, XIAP, SGSM2, GNB1, PHB2, STAMBP, MED27, CCR5, ZFHX3, EHD4, AP4S1, NKX2-8 (tumor)	AFP, HMGB1, NR3C1, CASP3, HLA-B, PSMB7, ING1, XIAP, SGSM2, GNB1, PHB2, STAMBP, MED27, CCR5, ZFHX3, EHD4, AP4S1, NKX2-8 (normal)

STAD (tumor)	STAD (normal)
AFP, HMGB1, NR3C1, CASP3, HLA-B, PSMB7, ING1, XIAP, SGSM2, GNB1, PHB2, STAMBP, MED27, CCR5, ZFHX3, EHD4, AP4S1, NKX2-8 (tumor)	AFP, HMGB1, NR3C1, CASP3, HLA-B, PSMB7, ING1, XIAP, SGSM2, GNB1, PHB2, STAMBP, MED27, CCR5, ZFHX3, EHD4, AP4S1, NKX2-8 (normal)

THCA (tumor)	THCA (normal)
AFP, HMGB1, NR3C1, CASP3, HLA-B, PSMB7, ING1, XIAP, SGSM2, GNB1, PHB2, STAMBP, MED27, CCR5, ZFHX3, EHD4, AP4S1, NKX2-8 (tumor)	AFP, HMGB1, NR3C1, CASP3, HLA-B, PSMB7, ING1, XIAP, SGSM2, GNB1, PHB2, STAMBP, MED27, CCR5, ZFHX3, EHD4, AP4S1, NKX2-8 (normal)

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TissGeneProg for AFP

Kaplan-Meier plots with logrank tests of overall survival (OS) using 28 cancer types
(TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16)
(TCGA clinicalMatrix, phenotype data, version 2016-04-27)
* Click on the image to enlarge it in a new window.

Kaplan-Meier plots with logrank test of relapse free survival (RFS) using 28 cancer types
(TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16)
(TCGA clinicalMatrix, phenotype data, version 2016-04-27)
* Click on the image enlarge it in a new window.

Forest plot of Cox proportional hazard ratio (HR) and 95% CI of overall survival (OS) using 28 cancer types
(TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16)
(TCGA clinicalMatrix, phenotype data, version 2016-04-27)
* Click on the image enlarge it in a new window.

Forest plot of Cox proportional hazard ratio (HR) and 95% CI of relapse free survival (RFS) using 28 cancer types
(TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16)
(TCGA clinicalMatrix, phenotype data, version 2016-04-27)
* Click on the image enlarge it in a new window.

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TissGeneClin for AFP

TissGeneDrug for AFP

Drug information targeting TissGene
(DrugBank Version 5.0.6, 2017-04-01)

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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TissGeneDisease for AFP

Disease information associated with TissGene
(DisGeNet, 2016-06-01)

Disease ID	Disease name	# pubmeds	Source
umls:C2239176	Liver carcinoma	425	BeFree,CTD_human,LHGDN
umls:C0023903	Liver neoplasms	83	BeFree,LHGDN
umls:C0019163	Hepatitis B	30	BeFree
umls:C0027627	Neoplasm Metastasis	30	BeFree
umls:C0345904	Malignant neoplasm of liver	30	BeFree
umls:C0023890	Liver Cirrhosis	26	BeFree
umls:C0013080	Down Syndrome	21	BeFree
umls:C0279000	Liver and Intrahepatic Biliary Tract Carcinoma	19	BeFree
umls:C0596263	Carcinogenesis	15	BeFree
umls:C1623038	Cirrhosis	15	BeFree
umls:C0521158	Recurrent tumor	12	BeFree
umls:C0699791	Stomach Carcinoma	12	BeFree
umls:C0004135	Ataxia Telangiectasia	11	BeFree
umls:C0023895	Liver diseases	10	BeFree,CTD_human
umls:C0024623	Malignant neoplasm of stomach	10	BeFree
umls:C1512409	Hepatocarcinogenesis	10	BeFree
umls:C0019348	Herpes Simplex Infections	9	BeFree
umls:C0205851	Germ cell tumor	9	BeFree
umls:C0004134	Ataxia	8	BeFree
umls:C0041107	Trisomy	8	BeFree
umls:C0152096	Complete trisomy 18 syndrome	8	BeFree
umls:C0206624	Hepatoblastoma	8	BeFree
umls:C0524910	Hepatitis C, Chronic	8	BeFree
umls:C0019158	Hepatitis	7	BeFree
umls:C0019159	Hepatitis A	7	BeFree
umls:C0008626	Congenital chromosomal disease	6	BeFree
umls:C0019189	Hepatitis, Chronic	6	BeFree
umls:C0206698	Cholangiocarcinoma	5	BeFree,LHGDN
umls:C0494165	Secondary malignant neoplasm of liver	5	BeFree
umls:C0001418	Adenocarcinoma	4	BeFree
umls:C0019196	Hepatitis C	4	BeFree
umls:C0178874	Tumor Progression	4	BeFree
umls:C0206659	Embryonal Carcinoma	4	BeFree
umls:C0278701	Gastric Adenocarcinoma	4	BeFree
umls:C0000768	Congenital Abnormality	3	BeFree
umls:C0014145	Yolk Sac Tumor	3	BeFree
umls:C0024299	Lymphoma	3	BeFree
umls:C0024620	Primary malignant neoplasm of liver	3	BeFree
umls:C0036631	Seminoma	3	BeFree
umls:C0039446	Telangiectasis	3	BeFree
umls:C0042769	Virus Diseases	3	BeFree
umls:C0260037	Multiple tumors	3	BeFree
umls:C0271270	Oculovestibuloauditory syndrome	3	BeFree
umls:C0346647	Malignant neoplasm of pancreas	3	BeFree
umls:C1318485	Liver regeneration disorder	3	BeFree
umls:C3163918	Tumor thrombus	3	BeFree
umls:C3489733	Oculomotor apraxia	3	BeFree
umls:C3501848	Nephrosis, congenital	3	BeFree
umls:C0004903	Beckwith-Wiedemann Syndrome	2	BeFree,LHGDN
umls:C0006142	Malignant neoplasm of breast	2	BeFree
umls:C0007758	Cerebellar Ataxia	2	BeFree
umls:C0012546	Diphtheria	2	BeFree
umls:C0029925	Ovarian Carcinoma	2	BeFree
umls:C0031117	Peripheral Neuropathy	2	BeFree
umls:C0036868	Sex Chromosome Aberrations	2	BeFree
umls:C0039538	Teratoma	2	BeFree
umls:C0149925	Small cell carcinoma of lung	2	BeFree
umls:C0153594	Malignant neoplasm of testis	2	BeFree
umls:C0235974	Pancreatic carcinoma	2	BeFree
umls:C0239946	Fibrosis, Liver	2	BeFree
umls:C0266159	Pyloric Atresia	2	BeFree
umls:C0275524	Coinfection	2	BeFree
umls:C0280100	Solid tumour	2	BeFree
umls:C0333693	Triploidy syndrome	2	BeFree
umls:C0334520	Teratoma, Malignant	2	BeFree
umls:C0442874	Neuropathy	2	BeFree
umls:C0677886	Epithelial ovarian cancer	2	BeFree
umls:C0678222	Breast Carcinoma	2	BeFree
umls:C0740279	Cerebellar atrophy	2	BeFree
umls:C0740380	Varicella zoster	2	BeFree
umls:C0795801	trisomy 2	2	BeFree
umls:C0855197	Testicular malignant germ cell tumor	2	BeFree
umls:C1266090	Hepatoid adenocarcinoma	2	BeFree
umls:C1336708	Testicular Germ Cell Tumor	2	BeFree
umls:C1519680	Tumor Immunity	2	BeFree
umls:C1853761	SPINOCEREBELLAR ATAXIA, AUTOSOMAL RECESSIVE 1	2	BeFree
umls:C0001430	Adenoma	1	BeFree
umls:C0002793	Anaplasia	1	BeFree
umls:C0003130	Anoxia	1	LHGDN
umls:C0003635	Apraxias	1	BeFree
umls:C0005411	Biliary Atresia	1	BeFree
umls:C0007102	Malignant tumor of colon	1	BeFree
umls:C0007137	Squamous cell carcinoma	1	BeFree
umls:C0009207	Cockayne Syndrome	1	BeFree
umls:C0010674	Cystic Fibrosis	1	BeFree
umls:C0011849	Diabetes Mellitus	1	BeFree
umls:C0013377	Dysgerminoma	1	BeFree
umls:C0013930	Embolism, Tumor	1	BeFree
umls:C0018050	Gonadal Disorders	1	BeFree
umls:C0019322	Umbilical hernia	1	BeFree
umls:C0020443	Hypercholesterolemia	1	BeFree
umls:C0020615	Hypoglycemia	1	BeFree
umls:C0022658	Kidney Diseases	1	BeFree
umls:C0022660	Kidney Failure, Acute	1	BeFree
umls:C0023893	Liver Cirrhosis, Experimental	1	CTD_human
umls:C0023904	Liver Neoplasms, Experimental	1	CTD_human
umls:C0024668	Mammary Neoplasms, Experimental	1	CTD_human
umls:C0026650	Movement Disorders	1	BeFree
umls:C0027613	Neonatal hepatitis	1	BeFree
umls:C0027658	Neoplasms, Germ Cell and Embryonal	1	LHGDN
umls:C0027773	Nesidioblastosis	1	BeFree
umls:C0028860	Oculocerebrorenal Syndrome	1	BeFree
umls:C0032580	Adenomatous Polyposis Coli	1	BeFree
umls:C0035369	Retroviridae Infections	1	BeFree
umls:C0038356	Stomach Neoplasms	1	CTD_human
umls:C0038454	Cerebrovascular accident	1	BeFree
umls:C0042721	Viral hepatitis	1	BeFree
umls:C0042963	Vomiting	1	BeFree
umls:C0080178	Spina Bifida	1	BeFree
umls:C0085548	Autosomal Recessive Polycystic Kidney Disease	1	BeFree
umls:C0085605	Liver Failure	1	BeFree
umls:C0151747	Renal tubular disorder	1	BeFree
umls:C0162530	Porphyria, Erythropoietic	1	BeFree
umls:C0162872	Aortic Aneurysm, Thoracic	1	BeFree
umls:C0205824	Liposarcoma, Dedifferentiated	1	BeFree
umls:C0206664	Teratocarcinoma	1	BeFree
umls:C0206666	Trophoblastic Tumor, Placental Site	1	BeFree
umls:C0206716	Ganglioglioma	1	BeFree
umls:C0206754	Neuroendocrine Tumors	1	LHGDN
umls:C0235325	Gastric hemorrhage	1	BeFree
umls:C0235833	Congenital diaphragmatic hernia	1	BeFree
umls:C0265706	Gastroschisis	1	BeFree
umls:C0270246	Meconium plug syndrome	1	BeFree
umls:C0279661	Acinar cell carcinoma of pancreas	1	BeFree
umls:C0332890	Congenital hemihypertrophy	1	BeFree
umls:C0334529	Hydatidiform Mole, Partial	1	BeFree
umls:C0341439	Chronic liver disease	1	BeFree
umls:C0346627	Intestinal Cancer	1	BeFree
umls:C0400936	Autoimmune liver disease	1	BeFree
umls:C0443306	Spastic	1	BeFree
umls:C0496870	Benign neoplasm of liver	1	BeFree
umls:C0524909	Hepatitis B, Chronic	1	BeFree
umls:C0546982	Cystic fibrosis with meconium ileus	1	BeFree
umls:C0677607	Hashimoto Disease	1	BeFree
umls:C0699790	Colon Carcinoma	1	BeFree
umls:C0796154	SIMPSON-GOLABI-BEHMEL SYNDROME, TYPE 1	1	BeFree
umls:C0877373	Advanced cancer	1	BeFree
umls:C0920350	Autoimmune thyroiditis	1	BeFree
umls:C0950121	Denys-Drash Syndrome	1	BeFree
umls:C1266158	Nonseminomatous germ cell tumor	1	BeFree
umls:C1285291	Fetal ascites	1	BeFree
umls:C1306503	Congenital exomphalos	1	BeFree
umls:C1368683	Epithelioma	1	BeFree
umls:C1384670	Single umbilical artery	1	BeFree
umls:C1389280	Basal ganglia calcification	1	BeFree
umls:C1458155	Mammary Neoplasms	1	CTD_human
umls:C1519670	Tumor Angiogenesis	1	BeFree
umls:C1833561	UV-Sensitive Syndrome	1	BeFree
umls:C1840311	Laryngeal cleft	1	BeFree
umls:C1856184	HEMIHYPERPLASIA, ISOLATED	1	BeFree
umls:C2939175	Meconium ileus	1	BeFree
umls:C2986703	Overgrowth Syndrome	1	BeFree
umls:C1863080	ALPHA-FETOPROTEIN, HEREDITARY PERSISTENCE OF	0	CLINVAR,ORPHANET
umls:C1863081	alpha-Fetoprotein Deficiency	0	CLINVAR,ORPHANET