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Bioinformatics and Systems Medicine Laboratory Bioinformatics and Systems Medicine Laboratory

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TissGeneSummary

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TissGeneExp

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TissGene-miRNA

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TissGeneMut: TissGeneSNV, TissGeneCNV, and TissGeneFusions

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TissGeneNet

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TissGeneProg

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TissGeneClin: TissGeneDrug and TissGeneDisease

TissGeneSummary for E2F1
check button Gene summary
Basic gene informationGene symbolE2F1
Gene nameE2F transcription factor 1
SynonymsE2F-1|RBAP1|RBBP3|RBP3
CytomapUCSC genome browser: 20q11.2
Type of geneprotein-coding
RefGenesNM_005225.2,
DescriptionPBR3PRB-binding protein E2F-1RBAP-1RBBP-3retinoblastoma-associated protein 1retinoblastoma-binding protein 3transcription factor E2F1
Modification date20141222
dbXrefs MIM : 189971
HGNC : HGNC
Ensembl : ENSG00000101412
HPRD : 01806
Vega : OTTHUMG00000032265
ProteinUniProt:
go to UniProt's Cross Reference DB Table
ExpressionCleanEX: HS_E2F1
BioGPS: 1869
PathwayNCI Pathway Interaction Database: E2F1
KEGG: E2F1
REACTOME: E2F1
Pathway Commons: E2F1
ContextiHOP: E2F1
ligand binding site mutation search in PubMed: E2F1
UCL Cancer Institute: E2F1
Assigned class in TissGDB*C
Included tissue-specific gene expression resourcesTiGER,GTEx
Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx)CervixTestis
Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA)CESCTGCT
Reference showing the relevant tissue of E2F1
Description by TissGene annotationsCancer gene
Have significant anti-correlated miRNA
TissgsLTS
Fused withTSGene
* Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C.

check button Gene ontology having evidence of Inferred from Direct Assay (IDA) from Entrez
GO IDGO termPubMed ID
GO:0006355regulation of transcription, DNA-templated12717439
GO:0010628positive regulation of gene expression15766563
GO:0048255mRNA stabilization15766563
GO:0006355regulation of transcription, DNA-templated12717439
GO:0010628positive regulation of gene expression15766563
GO:0048255mRNA stabilization15766563


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TissGeneExp for E2F1

check button Gene expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1))
(TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16)
gene exp


check button Gene isoform expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1))
(TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01)
gene isoform exp


check button Gene expressions across normal tissues of GTEx data
(GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct)
- Here, we shows the matched tissue types only among our 28 cancer types.
normal gene exp


check button Different expressions across 14 cancer types with more than 10 samples between matched tumors and normals (X-axis: cancer type and Y-axis: log2(norm_counts+1))
(TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16)
DEG exp

- Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05)
Cancer typeMean(exp) in tumorMean(exp) in matched normalLog2FCP-val.FDR
STAD0.196605734-1.8629786412.0595843753.39E-129.53E-10
LUSC0.009783431-1.7325773541.7423607846.32E-185.69E-17
BRCA-0.828644485-2.8653629062.0367184212.63E-334.30E-32
KICH-0.757406766-4.1535827663.3961761.18E-163.72E-15
KIRP-1.756631766-4.5021411412.7455093756.99E-162.24E-14
THCA-1.331486427-3.5585355792.2270491532.72E-232.08E-21
COAD0.373381696-1.2489683041.622355.62E-142.05E-12
LUAD-0.531030903-1.5529015931.021870693.87E-091.84E-08
KIRC-2.205467877-4.4256539882.2201861111.00E-271.52E-26
HNSC-0.425634672-1.914983511.4893488372.43E-141.40E-12
LIHC-0.430254766-4.0575247663.627271.28E-221.35E-20
ESCA-0.16825222-1.9386704021.7704181829.68E-050.003175741
BLCA-0.130154134-1.9758436081.8456894745.06E-050.000649306


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TissGene-miRNA for E2F1

check button Significantly anti-correlated miRNAs of TissGene across 28 cancer types
(Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016)
(TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21)
(TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16)
(Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25))
Cancer typemiRNA idmiRNA accessionP-val.Coeff.# samples
UVMhsa-miR-93-5pMIMAT00000930.021-0.2680
ACChsa-miR-362-3pMIMAT00046830.0098-0.3278
ACChsa-miR-362-3pMIMAT00046830.0098-0.3278


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TissGeneMut for E2F1
TissGeneSNV for E2F1

check button nsSNV counts per each loci.
Different colors of circles represent different cancer types. Circle size denotes number of samples.
(TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25)

* Click on the image to enlarge it in a new window.
SNV lollipop
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check button Somatic nucleotide variants of TissGene across 28 cancer types
(X-axis: cancer type and Y-axis: % of mutated samples)
The numbers in parentheses are numbers of samples with mutation (nsSNVs).
(TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25)
SNV distribution

- nsSNVs sorted by frequency.
AAchangeCancer type# samples
p.R166HPRAD1
p.G110SSKCM1
p.E280QUCEC1
p.C227FLUSC1
p.H98YSKCM1
p.R165QUCEC1
p.F391LESCA1
p.H406YSKCM1
p.Q99*BLCA1
p.R232CSTAD1
p.Q208LLIHC1
p.V295DUCEC1
p.R165QLUAD1
p.Q189XSKCM1
p.Q272LLIHC1
p.F437LLUAD1
p.G200SDLBC1
p.V246ASTAD1
p.S144RUCEC1
p.G291VLIHC1
p.E389KSKCM1
p.G363RBLCA1
p.R165WBRCA1
p.E301DESCA1
p.Y168CBRCA1
p.R138CUCS1
p.D148NLUSC1
p.L273HTHYM1
p.R252CBRCA1
p.Q189*SKCM1
p.V246AUCEC1
p.R252HPRAD1
p.S131*UCEC1
p.P299HUCEC1
p.R166HUCEC1
p.D426NLGG1
p.D294NSTAD1
p.P312QESCA1
p.R91TBLCA1
p.D294NSKCM1
p.P346SSKCM1
p.E321DUCEC1
p.I306VLUAD1
p.P346LSKCM1


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TissGeneCNV for E2F1

check button Copy number variations of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of CNV samples)
(TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16)
CNV


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TissGeneFusions for E2F1

check button Fusion genes including TissGene
(ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01)
DatabaseSrcCancer typeSampleFusion geneORF5'-gene BP3'-gene BP
Chimerdb3.0ChiTaRsNABQ962146E2F1-RDH11chr20:32274170chr14:68156930
Chimerdb3.0ChiTaRsNABG252912E2F1-E2F1chr20:32264041chr20:32263489
Chimerdb3.0FusionScanHNSCTCGA-HD-8314-01AE2F1-NECAB3Out-of-Framechr20:32264910chr20:32260228
Chimerdb3.0FusionScanCESCTCGA-MU-A5YI-01AE2F1-NECAB3Out-of-Framechr20:32264910chr20:32260228
Chimerdb3.0FusionScanBRCATCGA-AO-A128-01AE2F1-NECAB3Out-of-Framechr20:32264910chr20:32260228
Chimerdb3.0FusionScanBRCATCGA-AR-A0TS-01AE2F1-NECAB3Out-of-Framechr20:32264910chr20:32260228
Chimerdb3.0FusionScanESCATCGA-LN-A49L-01AE2F1-NECAB3Out-of-Framechr20:32264910chr20:32260228
Chimerdb3.0FusionScanESCATCGA-LN-A5U7-01AE2F1-NECAB3Out-of-Framechr20:32264910chr20:32260228
Chimerdb3.0FusionScanESCATCGA-LN-A49U-01AE2F1-NECAB3Out-of-Framechr20:32264910chr20:32260228
Chimerdb3.0FusionScanESCATCGA-L5-A88T-01AE2F1-NECAB3Out-of-Framechr20:32264910chr20:32260228
Chimerdb3.0FusionScanESCATCGA-VR-AA4G-01AE2F1-NECAB3Out-of-Framechr20:32264910chr20:32260228


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TissGeneNet for E2F1

check button Co-expressed gene networks based on protein-protein interaction data (CePIN)
(TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16)
(PINA2 ppi data)
BRCA (tumor)BRCA (normal)
E2F1, MAP3K5, RBL2, BAX, SETD1A, CDK1, CCNE1, BCL2, PURA, SIRT1, CCNA2, NPDC1, DNMT1, CDT1, FZR1, MYBL2, CDC25A, CTDP1, TERT, TIMELESS, RECQL4 (tumor)E2F1, CDK1, CDK2, CCNE1, CHEK2, RB1, CCNA2, DNMT1, CDT1, CDKN2C, MYBL2, CDC25A, LAPTM4B, TERT, CYC1, TIMELESS, IGF1, RECQL4, DBF4, ATAD2, PRDM2 (normal)
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COAD (tumor)COAD (normal)
E2F1, BRCA1, HDAC1, NDN, KAT2A, CDK1, CCNE1, SKP2, ATR, CHEK2, CCNA2, DNMT1, CDT1, TFDP1, MYBL2, CDC25A, TOPBP1, TIMELESS, RECQL4, DBF4, ATAD2 (tumor)E2F1, MAP3K5, BRCA1, E2F4, KAT2A, CDK1, CDK2, CCNE1, CHEK2, RBL1, DNMT1, CDT1, MYBL2, CDC25A, DUSP4, TOPBP1, TIMELESS, MIR17HG, RECQL4, DBF4, ATAD2 (normal)
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HNSC (tumor)HNSC (normal)
E2F1, HDAC3, BAX, E2F4, KAT2A, CDK1, CCNE1, CEBPA, CHEK2, SP4, TRIM28, CCNA2, DDB2, MCPH1, CDT1, MYBL2, CDC25A, PA2G4, TIMELESS, TP53BP1, RECQL4 (tumor)E2F1, BRCA1, BAX, PIN1, NRIP1, CDK1, CDK2, CHEK2, TRIM28, DDB2, CDK3, CDT1, CDKN2C, MYBL2, CDC25A, NRF1, TIMELESS, TFDP2, CBS, RECQL4, ATAD2 (normal)
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KICH (tumor)KICH (normal)
E2F1, TP53, BRCA1, CDKN2A, CDK1, CCNE1, TCF4, ATR, CHEK2, CCNA2, IFI16, DDB2, DNMT1, ATM, CDT1, MYBL2, DUSP4, TIMELESS, RECQL4, ATAD2, TRIM16 (tumor)E2F1, MAP3K5, PIN1, NRIP1, CDK1, CCNE1, RAB3GAP2, SIRT1, BECN1, NEDD8, RB1, CCNA2, CDT1, FZR1, CDKN2C, MYBL2, CDC25A, ARID3A, RECQL4, ZMYND10, ATAD2 (normal)
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KIRC (tumor)KIRC (normal)
E2F1, BRCA1, YWHAQ, CDK1, CDK2, CCNE1, TP73, CHEK2, CSNK1A1, CCNA2, DDB2, DNMT1, CDT1, MYBL2, DUSP4, TIMELESS, RECQL4, DBF4, ATAD2, TRIM16, STOML1 (tumor)E2F1, BAX, CDK1, CCNE1, TP73, BCL2, PURA, RAB3GAP2, SIRT1, CHEK2, TRIM28, RB1, CCNA2, ANAPC5, CDT1, MYBL2, CDC25A, TIMELESS, RECQL4, ATAD2, STOML1 (normal)
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KIRP (tumor)KIRP (normal)
E2F1, TP53, BAX, CDK1, CCNE1, STAT1, PURA, CHEK2, CCNA2, IFI16, DDB2, DNMT1, MYBL2, LAPTM4B, KDM1A, RECQL4, DBF4, ZMYND10, ATAD2, PRMT2, STOML1 (tumor)E2F1, BRCA1, NFKB1, E2F4, CCND1, CDK1, CCNE1, TP73, TRIM28, CCNA2, NPDC1, DNMT1, CDT1, MYBL2, CDC25A, CHL1, PA2G4, TIMELESS, DIRAS3, RECQL4, ATAD2 (normal)
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LIHC (tumor)LIHC (normal)
E2F1, GADD45B, CDKN2A, BAX, CDK1, CCNE1, STAT1, TP73, PURA, CEBPA, CSNK1A1, CEBPD, CCNA2, CDT1, FZR1, MYBL2, CDC25A, HDAC8, RECQL4, PRMT2, STOML1 (tumor)E2F1, BRCA1, CDKN2A, CDK1, CDK2, CCNE1, TP73, CCNA2, RBL1, DNMT1, CDT1, CDKN2C, MYBL2, CDC25A, TOPBP1, PA2G4, TIMELESS, RECQL4, DBF4, ZMYND10, ATAD2 (normal)
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LUAD (tumor)LUAD (normal)
E2F1, RBL2, HDAC3, TUBA4A, CDK1, CCNE1, KAT2B, TCF4, CEBPA, RAB3GAP2, SIRT1, SP4, CCNA2, MCPH1, CDT1, MYBL2, CDC25A, RNF144A, HDAC8, TIMELESS, RECQL4 (tumor)E2F1, BRCA1, RBL2, HDAC2, CDK1, CDK2, CCNE1, KAT2B, SKP2, CHEK2, CCNA2, RBL1, DNMT1, CDT1, MYBL2, CDC25A, TOPBP1, TIMELESS, RECQL4, DBF4, ATAD2 (normal)
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LUSC (tumor)LUSC (normal)
E2F1, HDAC3, BAX, CDK1, CCNE1, BIRC2, CEBPA, SKP2, SIRT1, UBXN1, SP4, CSNK1A1, CCNA2, DNMT1, CDT1, MYBL2, CDC25A, TIMELESS, RECQL4, STOML1, ARID4B (tumor)E2F1, MAP3K5, BRCA1, KAT2A, CDK1, CDK2, CCNE1, TRIM28, RB1, CCNA2, RBL1, DNMT1, CDT1, MYBL2, CDC25A, TOPBP1, TERT, NRF1, TIMELESS, RECQL4, ATAD2 (normal)
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PRAD (tumor)PRAD (normal)
E2F1, TP53, BRCA1, RBL2, TUBA4A, CDKN2A, CCNE1, KAT2B, BCL2, THBS1, CCNA2, PKIB, CDT1, PAX8, MYBL2, CDC25A, LEF1, PCSK6, TERT, HIST1H2AB, SNX19 (tumor)E2F1, BRCA1, KAT2A, CDK1, CCNE1, PURA, CHEK2, PDK4, NEDD8, TRIM28, CCNA2, CDT1, CDKN2C, MYBL2, CDC25A, CYC1, TIMELESS, DIRAS3, RECQL4, ZMYND10, PRDM2 (normal)
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STAD (tumor)STAD (normal)
E2F1, CDKN2A, HDAC1, NDN, CDK1, PURA, SIRT1, CHEK2, CCNA2, PKIB, CDT1, MYBL2, CDC25A, DUSP4, CTDP1, TERT, TIMELESS, TFDP2, TEAD3, RECQL4, CWC27 (tumor)E2F1, BRCA1, KAT2A, CDK1, CDK2, CCNE1, KAT2B, SKP2, CHEK2, TRIM28, CCNA2, RBL1, DNMT1, CDT1, MYBL2, CDC25A, SETD7, TIMELESS, RECQL4, ATAD2, PRMT2 (normal)
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THCA (tumor)THCA (normal)
E2F1, BIRC3, TUBA4A, CDKN2A, BAX, TNFSF11, CDK1, SPIB, CHEK2, CCNA2, DDB2, PARP1, DNMT1, CDT1, CDKN2C, MYBL2, DUSP4, ARID3A, TERT, DRAM1, RECQL4 (tumor)E2F1, CDKN1A, TUBA4A, BAX, BRD2, PIN1, CCNE1, TP73, UBXN1, SP4, SP3, DDB2, SIN3A, MCPH1, CDT1, MYBL2, TIMELESS, RECQL4, MGA, ARID4B, PRDM2 (normal)
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TissGeneProg for E2F1

check button Kaplan-Meier plots with logrank tests of overall survival (OS) using 28 cancer types
(TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16)
(TCGA clinicalMatrix, phenotype data, version 2016-04-27)

* Click on the image to enlarge it in a new window.
survival 1

check button Kaplan-Meier plots with logrank test of relapse free survival (RFS) using 28 cancer types
(TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16)
(TCGA clinicalMatrix, phenotype data, version 2016-04-27)

* Click on the image enlarge it in a new window.
survival 2

check button Forest plot of Cox proportional hazard ratio (HR) and 95% CI of overall survival (OS) using 28 cancer types
(TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16)
(TCGA clinicalMatrix, phenotype data, version 2016-04-27)

* Click on the image enlarge it in a new window.
survival 3

check button Forest plot of Cox proportional hazard ratio (HR) and 95% CI of relapse free survival (RFS) using 28 cancer types
(TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16)
(TCGA clinicalMatrix, phenotype data, version 2016-04-27)

* Click on the image enlarge it in a new window.
survival 4

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TissGeneClin for E2F1
TissGeneDrug for E2F1

check button Drug information targeting TissGene
(DrugBank Version 5.0.6, 2017-04-01)
DrugBank IDDrug nameDrug activityDrug typeDrug status


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TissGeneDisease for E2F1

check button Disease information associated with TissGene
(DisGeNet, 2016-06-01)
Disease IDDisease name# pubmedsSource
umls:C0035335Retinoblastoma29BeFree
umls:C0596263Carcinogenesis26BeFree
umls:C0678222Breast Carcinoma25BeFree
umls:C0006142Malignant neoplasm of breast23BeFree
umls:C2239176Liver carcinoma23BeFree,CTD_human
umls:C0376358Malignant neoplasm of prostate22BeFree
umls:C0600139Prostate carcinoma22BeFree
umls:C0025202melanoma16BeFree,CTD_human,LHGDN
umls:C0699791Stomach Carcinoma14BeFree
umls:C0027627Neoplasm Metastasis13BeFree
umls:C0007131Non-Small Cell Lung Carcinoma12BeFree
umls:C0024623Malignant neoplasm of stomach12BeFree
umls:C0007102Malignant tumor of colon11BeFree
umls:C0017638Glioma11BeFree,LHGDN
umls:C0699790Colon Carcinoma11BeFree
umls:C0178874Tumor Progression9BeFree
umls:C0009402Colorectal Carcinoma8BeFree
umls:C0025268Multiple Endocrine Neoplasia Type 2a8BeFree
umls:C0017636Glioblastoma7BeFree
umls:C0027819Neuroblastoma7BeFree
umls:C0029925Ovarian Carcinoma7BeFree
umls:C1140680Malignant neoplasm of ovary7BeFree,GAD
umls:C1458155Mammary Neoplasms7BeFree,CTD_human,LHGDN
umls:C1527249Colorectal Cancer7BeFree
umls:C0242379Malignant neoplasm of lung6BeFree
umls:C0279626Squamous cell carcinoma of esophagus6BeFree
umls:C0684249Carcinoma of lung6BeFree
umls:C0700095Central neuroblastoma6BeFree
umls:C1168401Squamous cell carcinoma of the head and neck6BeFree
umls:C0001418Adenocarcinoma5BeFree,LHGDN
umls:C0007137Squamous cell carcinoma5BeFree
umls:C0023467Leukemia, Myelocytic, Acute5BeFree
umls:C0023903Liver neoplasms5BeFree,LHGDN
umls:C0235974Pancreatic carcinoma5BeFree
umls:C0238198Gastrointestinal Stromal Tumors5BeFree
umls:C0005684Malignant neoplasm of urinary bladder4BeFree
umls:C0029463Osteosarcoma4BeFree
umls:C0033578Prostatic Neoplasms4BeFree,LHGDN
umls:C0037286Skin Neoplasms4BeFree
umls:C0038356Stomach Neoplasms4BeFree,LHGDN
umls:C0152013Adenocarcinoma of lung (disorder)4BeFree
umls:C0345904Malignant neoplasm of liver4BeFree
umls:C0346647Malignant neoplasm of pancreas4BeFree
umls:C0585442Osteosarcoma of bone4BeFree
umls:C0677886Epithelial ovarian cancer4BeFree,GAD
umls:C0686619Secondary malignant neoplasm of lymph node4BeFree
umls:C0699885Carcinoma of bladder4BeFree
umls:C0014859Esophageal Neoplasms3BeFree
umls:C0024121Lung Neoplasms3BeFree
umls:C0024299Lymphoma3BeFree
umls:C0032000Pituitary Adenoma3BeFree
umls:C0032002Pituitary Diseases3BeFree
umls:C0152018Esophageal carcinoma3BeFree
umls:C0302592Cervix carcinoma3BeFree
umls:C0546837Malignant neoplasm of esophagus3BeFree
umls:C0919267ovarian neoplasm3BeFree,LHGDN
umls:C1512409Hepatocarcinogenesis3BeFree
umls:C0001486Adenovirus Infections2BeFree
umls:C0002395Alzheimer's Disease2BeFree,LHGDN
umls:C0005695Bladder Neoplasm2BeFree
umls:C0006118Brain Neoplasms2BeFree,LHGDN
umls:C0007134Renal Cell Carcinoma2BeFree,LHGDN
umls:C0007847Malignant tumor of cervix2BeFree
umls:C0011265Presenile dementia2BeFree
umls:C0019693HIV Infections2BeFree
umls:C0023434Chronic Lymphocytic Leukemia2BeFree
umls:C0024141Lupus Erythematosus, Systemic2BeFree
umls:C0026764Multiple Myeloma2BeFree
umls:C0031511Pheochromocytoma2BeFree
umls:C0035334Retinitis Pigmentosa2BeFree
umls:C0149925Small cell carcinoma of lung2BeFree
umls:C0156312Atrophy of testis2BeFree
umls:C0279000Liver and Intrahepatic Biliary Tract Carcinoma2BeFree
umls:C0497327Dementia2BeFree,LHGDN
umls:C0555198Malignant Glioma2BeFree
umls:C0854723Retinal Dystrophies2BeFree
umls:C1261473Sarcoma2BeFree
umls:C1335302Pancreatic Ductal Adenocarcinoma2BeFree
umls:C1621958Glioblastoma Multiforme2BeFree
umls:C0000768Congenital Abnormality1BeFree
umls:C0004135Ataxia Telangiectasia1LHGDN
umls:C0006413Burkitt Lymphoma1BeFree
umls:C0007121Bronchogenic Carcinoma1BeFree
umls:C0007138Carcinoma, Transitional Cell1BeFree
umls:C0007873Uterine Cervical Neoplasm1LHGDN
umls:C0009375Colonic Neoplasms1LHGDN
umls:C0011065Cessation of life1LHGDN
umls:C0011875Diabetic Angiopathies1LHGDN
umls:C0011881Diabetic Nephropathy1BeFree
umls:C0013264Muscular Dystrophy, Duchenne1BeFree
umls:C0014072Experimental Autoimmune Encephalomyelitis1BeFree
umls:C0015672Fatigue1BeFree
umls:C0016057Fibrosarcoma1BeFree
umls:C0019163Hepatitis B1BeFree
umls:C0019196Hepatitis C1LHGDN
umls:C0020179Huntington Disease1RGD
umls:C0021367Mammary Ductal Carcinoma1BeFree
umls:C0022116Ischemia1BeFree
umls:C0022665Kidney Neoplasm1BeFree
umls:C0023269leiomyosarcoma1BeFree
umls:C0023418leukemia1BeFree
umls:C0023440Acute Erythroblastic Leukemia1BeFree
umls:C0023448Lymphoid leukemia1BeFree
umls:C0023473Myeloid Leukemia, Chronic1BeFree
umls:C0023890Liver Cirrhosis1BeFree
umls:C0024305Lymphoma, Non-Hodgkin1LHGDN
umls:C0025149Medulloblastoma1BeFree
umls:C0025500Mesothelioma1BeFree
umls:C0025517Metabolic Diseases1BeFree
umls:C0026010Microphthalmos1BeFree
umls:C0026640Mouth Neoplasms1LHGDN
umls:C0026850Muscular Dystrophy1BeFree
umls:C0026948Mycosis Fungoides1BeFree
umls:C0026985Myelodysplasia1BeFree
umls:C0027019Myelomonocytic leukemia1BeFree
umls:C0027051Myocardial Infarction1BeFree
umls:C0027126Myotonic Dystrophy1BeFree
umls:C0030521Parathyroid Neoplasms1BeFree
umls:C0030567Parkinson Disease1LHGDN
umls:C0032019Pituitary Neoplasms1BeFree
umls:C0032584polyps1BeFree
umls:C0032927Precancerous Conditions1BeFree
umls:C0033027Preleukemia1BeFree
umls:C0033375Prolactinoma1BeFree
umls:C0035309Retinal Diseases1BeFree
umls:C0040136Thyroid Neoplasm1BeFree
umls:C0079744Diffuse Large B-Cell Lymphoma1BeFree
umls:C0079773Lymphoma, T-Cell, Cutaneous1BeFree
umls:C0085669Acute leukemia1BeFree
umls:C0151468Thyroid Gland Follicular Adenoma1BeFree
umls:C0151779Cutaneous Melanoma1BeFree
umls:C0153633Malignant neoplasm of brain1BeFree
umls:C0205647Follicular adenoma1BeFree
umls:C0206655Alveolar rhabdomyosarcoma1BeFree
umls:C0206682Follicular thyroid carcinoma1BeFree
umls:C0220633Uveal melanoma1BeFree
umls:C0238461Anaplastic thyroid carcinoma1BeFree
umls:C0238462Medullary carcinoma of thyroid1BeFree
umls:C0239946Fibrosis, Liver1BeFree
umls:C0263641Epithelial hyperplasia of skin1BeFree
umls:C0271183Severe myopia1BeFree
umls:C0271933Congenital dyserythropoietic anemia, type I1BeFree
umls:C0275524Coinfection1BeFree
umls:C0278484Malignant neoplasm of colon stage IV1BeFree
umls:C0278838Prostate cancer recurrent1BeFree
umls:C0278883Metastatic melanoma1BeFree
umls:C0279702Conventional (Clear Cell) Renal Cell Carcinoma1BeFree
umls:C0334634Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse1BeFree
umls:C0346429Multiple malignancy1BeFree
umls:C0374997Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site1BeFree
umls:C0409974Lupus Erythematosus1BeFree
umls:C0410226Congenital Myotonic Dystrophy1BeFree
umls:C0494165Secondary malignant neoplasm of liver1BeFree
umls:C0520571Fibrosis of bile duct1BeFree
umls:C0598766Leukemogenesis1BeFree
umls:C0730321Punctate inner choroidopathy1BeFree
umls:C0850741Smoker's lung1BeFree
umls:C0877373Advanced cancer1BeFree
umls:C1336077Sporadic Burkitt's lymphoma1BeFree
umls:C1337012Well Differentiated Papillary Mesothelioma1BeFree
umls:C1377610Peritoneal Mesothelioma1BeFree
umls:C1510885Angiogenic Switch1BeFree
umls:C1518296Neuropathogenesis1BeFree
umls:C1519670Tumor Angiogenesis1BeFree
umls:C1520166Xenograft Model1BeFree
umls:C1527349Ductal Breast Carcinoma1BeFree
umls:C1623038Cirrhosis1BeFree
umls:C1709246Non-Neoplastic Disorder1BeFree
umls:C1847540Azoospermia, Nonobstructive1BeFree
umls:C2349952Oropharyngeal Carcinoma1BeFree
umls:C2931822Nasopharyngeal carcinoma1BeFree
umls:C3241937Nonalcoholic Steatohepatitis1BeFree
umls:C3463824MYELODYSPLASTIC SYNDROME1LHGDN
umls:C3539878Triple Negative Breast Neoplasms1BeFree
umls:C3714514Infection1LHGDN
umls:C0011854Diabetes Mellitus, Insulin-Dependent0MGD
umls:C1527336Sjogren's Syndrome0MGD