TissGDB
Tissglogo

Home

Download

 Statistics

 Landscape

Help

Contact

Bioinformatics and Systems Medicine Laboratory Bioinformatics and Systems Medicine Laboratory

bullet point

TissGeneSummary

bullet point

TissGeneExp

bullet point

TissGene-miRNA

bullet point

TissGeneMut: TissGeneSNV, TissGeneCNV, and TissGeneFusions

bullet point

TissGeneNet

bullet point

TissGeneProg

bullet point

TissGeneClin: TissGeneDrug and TissGeneDisease

TissGeneSummary for ALB
check button Gene summary
Basic gene informationGene symbolALB
Gene namealbumin
SynonymsANALBA|FDAH|PRO0883|PRO0903|PRO1341
CytomapUCSC genome browser: 4q13.3
Type of geneprotein-coding
RefGenesNM_000477.5,
Descriptionalbumin (32 AA)albumin (AA 34)cell growth inhibiting protein 42growth-inhibiting protein 20serum albumin
Modification date20141207
dbXrefs MIM : 103600
HGNC : HGNC
Ensembl : ENSG00000163631
HPRD : 00062
Vega : OTTHUMG00000129919
ProteinUniProt:
go to UniProt's Cross Reference DB Table
ExpressionCleanEX: HS_ALB
BioGPS: 213
PathwayNCI Pathway Interaction Database: ALB
KEGG: ALB
REACTOME: ALB
Pathway Commons: ALB
ContextiHOP: ALB
ligand binding site mutation search in PubMed: ALB
UCL Cancer Institute: ALB
Assigned class in TissGDB*A
Included tissue-specific gene expression resourcesHPA,TiGER,GTEx
Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx)Liver
Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA)LIHC
Reference showing the relevant tissue of ALBDifferentiation of bone mesenchymal stem cells into hepatocyte-like cells induced by liver tissue homogenate. Xing XK, Feng HG, Yuan ZQ. Genet Mol Res. 2016 Jul 15;15(3). doi: 10.4238/gmr.15038550. (pmid:27525848)
go to article
Description by TissGene annotationsCancer gene
TissgsKTS
CNV gained TissGeneKTS
Fused withTSGene
* Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C.

check button Gene ontology having evidence of Inferred from Direct Assay (IDA) from Entrez
GO IDGO termPubMed ID
GO:0009267cellular response to starvation16245148
GO:0019836hemolysis by symbiont of host erythrocytes16394536
GO:0043066negative regulation of apoptotic process16153637
GO:0051659maintenance of mitochondrion location16153637
GO:0009267cellular response to starvation16245148
GO:0019836hemolysis by symbiont of host erythrocytes16394536
GO:0043066negative regulation of apoptotic process16153637
GO:0051659maintenance of mitochondrion location16153637


Top
TissGeneExp for ALB

check button Gene expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1))
(TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16)
gene exp


check button Gene isoform expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1))
(TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01)
gene isoform exp


check button Gene expressions across normal tissues of GTEx data
(GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct)
- Here, we shows the matched tissue types only among our 28 cancer types.
normal gene exp


check button Different expressions across 14 cancer types with more than 10 samples between matched tumors and normals (X-axis: cancer type and Y-axis: log2(norm_counts+1))
(TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16)
DEG exp

- Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05)
Cancer typeMean(exp) in tumorMean(exp) in matched normalLog2FCP-val.FDR
KICH-2.8813868933.712625107-6.5940121.38E-087.14E-08
KIRC-0.3436297824.472875773-4.8165055561.04E-145.12E-14
KIRP-1.7760721435.469727857-7.24582.43E-134.39E-12
BRCA-0.8845891393.046224019-3.9308131583.75E-182.33E-17
LIHC14.8125131117.44829111-2.6357781.12E-091.21E-08


Top
TissGene-miRNA for ALB

check button Significantly anti-correlated miRNAs of TissGene across 28 cancer types
(Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016)
(TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21)
(TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16)
(Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25))
Cancer typemiRNA idmiRNA accessionP-val.Coeff.# samples


Top
TissGeneMut for ALB
TissGeneSNV for ALB

check button nsSNV counts per each loci.
Different colors of circles represent different cancer types. Circle size denotes number of samples.
(TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25)

* Click on the image to enlarge it in a new window.
SNV lollipop
bullet point


check button Somatic nucleotide variants of TissGene across 28 cancer types
(X-axis: cancer type and Y-axis: % of mutated samples)
The numbers in parentheses are numbers of samples with mutation (nsSNVs).
(TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25)
SNV distribution

- nsSNVs sorted by frequency.
AAchangeCancer type# samples
p.L179FSKCM2
p.G455ESKCM2
p.R434CSKCM2
p.R138QSKCM2
p.L540ILUAD1
p.S217FCHOL1
p.A25VPAAD1
p.I288NSTAD1
p.A374SLIHC1
p.A234DOV1
p.V517LLUAD1
p.P142LSKCM1
p.E124DTHCA1
p.C302FLIHC1
p.P523SUCS1
p.P390SLGG1
p.D62ELIHC1
p.D283NSKCM1
p.E155KSKCM1
p.G231ESKCM1
p.V433FGBM1
p.S617YUCEC1
p.A585SHNSC1
p.E392KSKCM1
p.P171TREAD1
p.R138QGBM1
p.C277WSKCM1
p.D145NBLCA1
p.V506APAAD1
p.A237TREAD1
p.S513LSKCM1
p.R169ILUAD1
p.V259EHNSC1
p.E525KSKCM1
p.E268KLIHC1
p.L487VLIHC1
p.G20DUCEC1
p.S478FSKCM1
p.S541FSKCM1
p.P445LSKCM1
p.V497DLIHC1
p.S311FSKCM1
p.P390SUCEC1
p.N507KLUAD1
p.L540HGBM1
p.F592VSTAD1
p.R24QKIRC1
p.Y174HLIHC1
p.D80YBLCA1
p.E268XTHYM1
p.Y162NSTAD1
p.D207NSKCM1
p.P248SSKCM1
p.R23CSKCM1
p.E84QLIHC1
p.D197GUCEC1
p.K36RLIHC1
p.M572ISKCM1
p.S504FESCA1
p.584_585KA>NSHNSC1
p.I537VKIRC1
p.Y54FUCEC1
p.R210WUCEC1
p.E276*SKCM1
p.E589*LUAD1
p.V334AHNSC1
p.E165DCOAD1
p.D279NBLCA1
p.V356APAAD1
p.H152YSKCM1
p.E301KHNSC1
p.Y174FOV1
p.D211NSKCM1
p.P561SLIHC1
p.D587NSKCM1
p.S226GCOAD1
p.E566QUCEC1
p.P176ALIHC1
p.E417KCESC1
p.R138*UCEC1
p.L454QHNSC1
p.V367ALIHC1
p.Y17CLIHC1
p.R23HHNSC1
p.H170YLUSC1
p.E316KUCEC1
p.E268KHNSC1
p.P327SUCEC1
p.R210WCOAD1
p.R545KBLCA1
p.D279YLUAD1
p.R434PSKCM1
p.E191AKIRP1
p.P561RLIHC1
p.E268VBLCA1
p.A602SLIHC1
p.S8FLUSC1
p.E156VCHOL1
p.F13ISKCM1
p.L104VHNSC1
p.D364EUCEC1
p.A26GLUSC1
p.V405ALIHC1
p.S216LSKCM1
p.T520KTHYM1
p.K543ELIHC1
p.R105LHNSC1
p.E309KSKCM1
p.K584NHNSC1
p.A112VHNSC1
p.E424KSKCM1
p.D283EGBM1
p.E529KLUSC1
p.R24QCOAD1
p.T380NLUAD1
p.E121QHNSC1
p.R372SBLCA1
p.Q228KSKCM1
p.S294LSKCM1
p.D348NSKCM1
p.R434CSTAD1
p.R34WSKCM1
p.E268KSKCM1


Top
TissGeneCNV for ALB

check button Copy number variations of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of CNV samples)
(TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16)
CNV


Top
TissGeneFusions for ALB

check button Fusion genes including TissGene
(ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01)
DatabaseSrcCancer typeSampleFusion geneORF5'-gene BP3'-gene BP
Chimerdb3.0ChiTaRsNABP294362ALB-SERPING1chr4:74274476chr11:57381845
Chimerdb3.0ChiTaRsNADA643030EBNA1BP2-ALBchr1:43713713chr4:74270084
Chimerdb3.0ChiTaRsNAAI133546ALB-ZDHHC2chr4:74286029chr8:17078894
Chimerdb3.0ChiTaRsNAAW072570ALB-APPchr4:74286971chr21:27354655
Chimerdb3.0ChiTaRsNAAI174891ACTR3-ALBchr2:114677671chr4:74270078
Chimerdb3.0ChiTaRsNAAF116711ALB-RPS4Y1chr4:74283280chrY:2709643
Chimerdb3.0ChiTaRsNAAI064841RABGAP1L-ALBchr1:174189518chr4:74283248
Chimerdb3.0ChiTaRsNAAI114561MSL3-ALBchrX:11778966chr4:74283960
Chimerdb3.0ChiTaRsNAW86731ALB-VPS13Bchr4:74279288chr8:100222381
Chimerdb3.0ChiTaRsNAAI065112ALB-TFchr4:74286942chr3:133497528
Chimerdb3.0ChiTaRsNABG545312ALB-MALAT1chr4:74274400chr11:65267378
Chimerdb3.0ChiTaRsNAAI114654ALB-ALBchr4:74285332chr4:74279251
Chimerdb3.0ChiTaRsNAAI133207SASH3-ALBchrX:128929147chr4:74270004
Chimerdb3.0ChiTaRsNAAV654807ABLIM3-ALBchr5:148534277chr4:74270030
Chimerdb3.0ChiTaRsNAAI064877ALB-ALBchr4:74282070chr4:74283298
Chimerdb3.0ChiTaRsNAAF116688MATR3-ALBchr5:138632200chr4:74287034
Chimerdb3.0ChiTaRsNAAI110818ALB-ALBchr4:74284021chr4:74279160
Chimerdb3.0ChiTaRsNAAU120466ARID4B-ALBchr1:235456218chr4:74270005
Chimerdb3.0ChiTaRsNAAI207513ALB-SETD4chr4:74270868chr21:37444788
Chimerdb3.0ChiTaRsNAAI114516STK38L-ALBchr12:27476263chr4:74279302
Chimerdb3.0ChiTaRsNAAF119890GABPA-ALBchr21:27142279chr4:74277769
Chimerdb3.0ChiTaRsNAAF119840CMAS-ALBchr12:22215952chr4:74270004
Chimerdb3.0ChiTaRsNAAF118090ZNF536-ALBchr19:30864332chr4:74279313
Chimerdb3.0ChiTaRsNABG563936MYO18A-ALBchr17:27405893chr4:74280437
Chimerdb3.0ChiTaRsNADQ145726TXNL4B-ALBchr16:72094903chr4:74285996
Chimerdb3.0TopHat-FusionCHOLTCGA-W5-AA34-11AALB-TFCDS-3'UTRchr4:74283351chr3:133497492
Chimerdb3.0TopHat-FusionCHOLTCGA-W5-AA2R-11AALB-SERPING1CDS-3'UTRchr4:74280802chr11:57382101
Chimerdb3.0TopHat-FusionCHOLTCGA-ZU-A8S4-11AALB-SERPING1CDS-3'UTRchr4:74280817chr11:57382085
Chimerdb3.0TopHat-FusionCHOLTCGA-W5-AA2X-11AALB-TFIn-Framechr4:74272402chr3:133495984
Chimerdb3.0TopHat-FusionCHOLTCGA-W5-AA31-11AALB-TFOut-of-Framechr4:74285355chr3:133475820
TCGAfusionPortalPRADABRCATCGA-AR-A5QN-01AALB-SIAE3UTR-5UTRChr4:74286971Chr11:124543777


Top
TissGeneNet for ALB

check button Co-expressed gene networks based on protein-protein interaction data (CePIN)
(TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16)
(PINA2 ppi data)
BRCA (tumor)BRCA (normal)
ALB, TK1, YWHAG, PFDN1, LUC7L2, ADRA1B, IMMT, ZNF232, KLK3, GABBR1, LRP2, KRT14, AMBP, TLN2, CDCP1, CUBN, KRT9, F7, PDE4B, CACNA1I, KCNMA1 (tumor)ALB, TK1, KIAA0101, YWHAG, FN1, NR5A2, FCGRT, PSMA3, HNF1A, IMMT, TTR, FGA, TF, KLK3, LRP2, CDC45, KRT14, AMBP, CDCP1, F7, KCNMA1 (normal)
bullet pointbullet point
COAD (tumor)COAD (normal)
ALB, USP37, APOE, LUC7L2, IL7R, ATM, ZNF232, FGA, ST13, TF, HP, AMBP, RLF, SRGN, ORM1, AGA, RBP4, CDCP1, PLAG1, PDE4B, APOC1 (tumor)ALB, TK1, NFKB1, CTSL1, FN1, KRT1, PFDN1, PSMA3, TTR, DDB1, APOA1, FGA, TF, HP, CDC45, AMBP, RLF, SRGN, ORM1, PDE4B, PON1 (normal)
bullet pointbullet point
HNSC (tumor)HNSC (normal)
ALB, CEBPB, USP37, CTSL1, APOE, KRT1, LUC7L2, TTR, KRT10, APOA1, FGA, HP, AMBP, RLF, EEF2K, ORM1, RBP4, KRT9, SETX, PON1, APOC1 (tumor)ALB, FN1, PSMA3, IL7R, TTR, APOA1, ZNF232, FGA, KLK3, GABBR1, HP, AMBP, RLF, ORM1, AGA, RBP4, CUBN, F7, PDE4B, KCNMA1, PON1 (normal)
bullet pointbullet point
KICH (tumor)KICH (normal)
ALB, TK1, APOE, NR5A2, FCGRT, PITX3, HNF1A, TTR, ATM, APOA1, FGA, ST13, KLK3, CRYAA, GABBR1, LRP2, ZFHX3, RBP4, CUBN, PON1, APOC1 (tumor)ALB, FBXO25, TK1, USP37, CTSL1, FN1, NR5A2, ADRA1B, IL7R, TTR, KRT10, ZNF232, GABBR1, AMBP, EEF2K, ZFHX3, TLN2, DBP, PLAG1, CACNA1I, KCNMA1 (normal)
bullet pointbullet point
KIRC (tumor)KIRC (normal)
ALB, FBXO25, TK1, APOE, NR5A2, FCGRT, UIMC1, PITX3, HNF1A, IL7R, TTR, APOA1, ST13, KLK3, CRYAA, LRP2, AMBP, SRGN, RBP4, CUBN, F7 (tumor)ALB, YWHAG, PFDN1, ADRA1B, HNF1A, TTR, APOA1, FGA, TF, CRYAA, AMBP, ORM1, TLN2, RBP4, CDCP1, DBP, F7, SETX, PON1, OR2T6, OR8D2 (normal)
bullet pointbullet point
KIRP (tumor)KIRP (normal)
ALB, FBXO25, TK1, APOE, NR5A2, FCGRT, UIMC1, PITX3, LUC7L2, HNF1A, TTR, APOA1, ST13, CRYAA, GABBR1, LRP2, CDC45, TLN2, RBP4, CUBN, PON1 (tumor)ALB, FBXO25, NFKB1, YWHAG, PFDN1, LUC7L2, HNF1A, IL7R, TTR, DDB1, APOA1, FGA, TF, HP, AMBP, SRGN, ORM1, ZFHX3, CDCP1, CUBN, PON1 (normal)
bullet pointbullet point
LIHC (tumor)LIHC (normal)
ALB, FBXO25, FN1, APOE, FCGRT, LUC7L2, HNF1A, DMWD, TTR, APOA1, ST13, TF, AMBP, ORM1, RBP4, CDCP1, DBP, F7, SETX, PON1, APOC1 (tumor)ALB, FN1, APOE, PFDN1, NR5A2, UIMC1, HNF1A, DMWD, TTR, APOA1, FGA, TF, CRYAA, HP, AMBP, ORM1, RBP4, CDCP1, F7, PON1, APOC1 (normal)
bullet pointbullet point
LUAD (tumor)LUAD (normal)
ALB, TK1, KIAA0101, ADRA1B, PSMA3, HNF1A, DMWD, IMMT, ATM, RYR2, CRYAA, GABBR1, AMBP, RLF, EEF2K, ORM1, AGA, RBP4, CUBN, KCNMA1, PRB3 (tumor)ALB, TK1, KIAA0101, CEBPB, YWHAG, CTSL1, KRT1, PFDN1, NR5A2, HNF1A, TTR, APOA1, ZNF232, TF, CDC45, AMBP, EEF2K, SRGN, CUBN, PON1, OR8D2 (normal)
bullet pointbullet point
LUSC (tumor)LUSC (normal)
ALB, KRT1, PSMA3, HNF1A, DMWD, KRT10, DDB1, APOA1, TF, HP, KRT14, AMBP, EEF2K, ZFHX3, AGA, CDCP1, KRT9, F7, PON1, APOC1, GJC2 (tumor)ALB, PITX3, HNF1A, TTR, DDB1, APOA1, PSMD4, ZNF232, FGA, TF, KLK3, CRYAA, AMBP, RBP4, CDCP1, CUBN, DBP, F7, PON1, OR2T6, GJC2 (normal)
bullet pointbullet point
PRAD (tumor)PRAD (normal)
ALB, FBXO25, TK1, KIAA0101, FN1, HNF1A, TTR, DDB1, ATM, ST13, KLK3, CDC45, KRT14, AMBP, ZFHX3, TLN2, AGA, KRT9, PLAG1, SETX, PRB3 (tumor)ALB, KIAA0101, NFKB1, APOE, PFDN1, HNF1A, IL7R, TTR, KRT10, DDB1, APOA1, ZNF232, FGA, CRYAA, AMBP, RLF, ZFHX3, CDCP1, SETX, KCNMA1, APOC1 (normal)
bullet pointbullet point
STAD (tumor)STAD (normal)
ALB, FBXO25, TK1, YWHAG, FN1, APOE, LUC7L2, HNF1A, IL7R, TTR, FGA, GABBR1, CDC45, AMBP, RLF, SRGN, ORM1, ZFHX3, KRT9, PDE4B, APOC1 (tumor)ALB, NR5A2, FCGRT, HNF1A, TTR, APOA1, FGA, TF, CRYAA, HP, LRP2, AMBP, ORM1, AGA, RBP4, PLAG1, F7, CACNA1I, PON1, PRB3, OR8D2 (normal)
bullet pointbullet point
THCA (tumor)THCA (normal)
ALB, TK1, KIAA0101, YWHAG, KRT1, LUC7L2, ADRA1B, IMMT, APOA1, FGA, RYR2, GABBR1, CDC45, AMBP, SRGN, AGA, CUBN, PLAG1, CACNA1I, KCNMA1, PRB3 (tumor)ALB, NFKB1, YWHAG, FN1, FCGRT, IL7R, IMMT, TTR, KRT10, DDB1, APOA1, FGA, TF, GABBR1, HP, AMBP, ORM1, CDCP1, CUBN, CACNA1I, PON1 (normal)
bullet pointbullet point


Top
TissGeneProg for ALB

check button Kaplan-Meier plots with logrank tests of overall survival (OS) using 28 cancer types
(TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16)
(TCGA clinicalMatrix, phenotype data, version 2016-04-27)

* Click on the image to enlarge it in a new window.
survival 1

check button Kaplan-Meier plots with logrank test of relapse free survival (RFS) using 28 cancer types
(TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16)
(TCGA clinicalMatrix, phenotype data, version 2016-04-27)

* Click on the image enlarge it in a new window.
survival 2

check button Forest plot of Cox proportional hazard ratio (HR) and 95% CI of overall survival (OS) using 28 cancer types
(TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16)
(TCGA clinicalMatrix, phenotype data, version 2016-04-27)

* Click on the image enlarge it in a new window.
survival 3

check button Forest plot of Cox proportional hazard ratio (HR) and 95% CI of relapse free survival (RFS) using 28 cancer types
(TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16)
(TCGA clinicalMatrix, phenotype data, version 2016-04-27)

* Click on the image enlarge it in a new window.
survival 4

Top
TissGeneClin for ALB
TissGeneDrug for ALB

check button Drug information targeting TissGene
(DrugBank Version 5.0.6, 2017-04-01)
DrugBank IDDrug nameDrug activityDrug typeDrug status


Top
TissGeneDisease for ALB

check button Disease information associated with TissGene
(DisGeNet, 2016-06-01)
Disease IDDisease name# pubmedsSource
umls:C2239176Liver carcinoma97BeFree,LHGDN
umls:C0022658Kidney Diseases49BeFree,CTD_human,LHGDN
umls:C0023903Liver neoplasms45BeFree
umls:C0730345Microalbuminuria45BeFree
umls:C0011881Diabetic Nephropathy41BeFree,CTD_human,RGD
umls:C0011849Diabetes Mellitus40BeFree
umls:C0011847Diabetes38BeFree
umls:C0011860Diabetes Mellitus, Non-Insulin-Dependent37BeFree,GAD,LHGDN
umls:C0342185Hyperthyroxinemia, Familial Dysalbuminemic30BeFree,CLINVAR,CTD_human
umls:C0011854Diabetes Mellitus, Insulin-Dependent22BeFree
umls:C0020538Hypertensive disease21BeFree,CTD_human
umls:C0019163Hepatitis B17BeFree
umls:C0023890Liver Cirrhosis16BeFree,CTD_human
umls:C0007222Cardiovascular Diseases14BeFree,CTD_human
umls:C0022661Kidney Failure, Chronic12BeFree,CTD_human
umls:C0023895Liver diseases12BeFree,GAD
umls:C0017658Glomerulonephritis10BeFree,CTD_human
umls:C0019693HIV Infections10BeFree,CTD_human
umls:C1623038Cirrhosis10BeFree
umls:C0010068Coronary heart disease9BeFree,LHGDN
umls:C0033687Proteinuria9CTD_human
umls:C0017665Membranous glomerulonephritis8BeFree,CTD_human
umls:C1956346Coronary Artery Disease8BeFree,LHGDN
umls:C0010054Coronary Arteriosclerosis7BeFree
umls:C0035309Retinal Diseases7BeFree
umls:C1561643Chronic Kidney Diseases7BeFree
umls:C2316810Chronic kidney disease stage 57BeFree
umls:C0004153Atherosclerosis6BeFree,LHGDN
umls:C0006142Malignant neoplasm of breast6BeFree
umls:C0027697Nephritis6CTD_human
umls:C0038454Cerebrovascular accident6BeFree,CTD_human
umls:C0239981Hypoalbuminemia6BeFree,CTD_human
umls:C0678222Breast Carcinoma6BeFree
umls:C0003850Arteriosclerosis5BeFree
umls:C0008626Congenital chromosomal disease5BeFree
umls:C0011884Diabetic Retinopathy5BeFree
umls:C0019158Hepatitis5BeFree,CTD_human,LHGDN
umls:C0027726Nephrotic Syndrome5BeFree,CTD_human
umls:C0162429Malnutrition5BeFree
umls:C0206698Cholangiocarcinoma5BeFree
umls:C1512409Hepatocarcinogenesis5BeFree
umls:C0009402Colorectal Carcinoma4BeFree
umls:C0011265Presenile dementia4BeFree
umls:C0019159Hepatitis A4BeFree
umls:C0019196Hepatitis C4BeFree
umls:C0027627Neoplasm Metastasis4BeFree
umls:C0027707Nephritis, Interstitial4CTD_human
umls:C0028754Obesity4BeFree
umls:C0035078Kidney Failure4BeFree
umls:C0042769Virus Diseases4BeFree
umls:C0162557Liver Failure, Acute4BeFree,CTD_human
umls:C0178664Glomerulosclerosis (disorder)4BeFree
umls:C0497327Dementia4BeFree
umls:C0699791Stomach Carcinoma4BeFree
umls:C0745744End Stage Liver Disease4BeFree
umls:C0003873Rheumatoid Arthritis3BeFree
umls:C0009324Ulcerative Colitis3BeFree
umls:C0014544Epilepsy3BeFree,CTD_human
umls:C0020456Hyperglycemia3BeFree
umls:C0021051Immunologic Deficiency Syndromes3BeFree
umls:C0022116Ischemia3BeFree
umls:C0023893Liver Cirrhosis, Experimental3CTD_human
umls:C0024623Malignant neoplasm of stomach3BeFree
umls:C0025290Aseptic Meningitis3CTD_human
umls:C0026764Multiple Myeloma3BeFree
umls:C0034063Pulmonary Edema3BeFree
umls:C0085110Severe Combined Immunodeficiency3BeFree
umls:C0152025Polyneuropathy3BeFree
umls:C0206624Hepatoblastoma3BeFree
umls:C0239946Fibrosis, Liver3BeFree
umls:C0268731Renal glomerular disease3BeFree
umls:C0279000Liver and Intrahepatic Biliary Tract Carcinoma3BeFree
umls:C0345904Malignant neoplasm of liver3BeFree
umls:C0494165Secondary malignant neoplasm of liver3BeFree
umls:C0524909Hepatitis B, Chronic3BeFree
umls:C0596263Carcinogenesis3BeFree
umls:C1527249Colorectal Cancer3BeFree
umls:C1559271Non-Malignant Ascites Adverse Event3BeFree
umls:C2609414Acute kidney injury3CTD_human
umls:C0001418Adenocarcinoma2BeFree
umls:C0002395Alzheimer's Disease2BeFree
umls:C0002871Anemia2BeFree,LHGDN
umls:C0004698Balkan Nephropathy2BeFree
umls:C0010346Crohn Disease2BeFree,LHGDN
umls:C0014072Experimental Autoimmune Encephalomyelitis2BeFree
umls:C0015672Fatigue2BeFree
umls:C0015695Fatty Liver2BeFree,LHGDN
umls:C0018801Heart failure2BeFree,CTD_human
umls:C0019069Hemophilia A2BeFree
umls:C0019189Hepatitis, Chronic2BeFree
umls:C0019243Angioedemas, Hereditary2BeFree
umls:C0020443Hypercholesterolemia2BeFree
umls:C0020476Hyperlipoproteinemias2BeFree
umls:C0020551Hyperthyroxinemia2BeFree
umls:C0020649Hypotension2CTD_human
umls:C0022660Kidney Failure, Acute2BeFree
umls:C0027720Nephrosis2BeFree,CTD_human
umls:C0029925Ovarian Carcinoma2BeFree
umls:C0036202Sarcoidosis2BeFree
umls:C0036830Serum Sickness2CTD_human
umls:C0042373Vascular Diseases2BeFree
umls:C0085207Gestational Diabetes2BeFree
umls:C0278488Carcinoma breast stage IV2BeFree
umls:C0333980Focal Nodular Hyperplasia2BeFree
umls:C0341439Chronic liver disease2BeFree
umls:C0375023Respiratory syncytial virus (RSV) infection in conditions classified elsewhere and of unspecified site2BeFree
umls:C0391861Plasma cell inflammation2BeFree
umls:C0403447Chronic Kidney Insufficiency2BeFree
umls:C0524620Metabolic Syndrome X2BeFree
umls:C0524910Hepatitis C, Chronic2BeFree
umls:C0740380Varicella zoster2BeFree
umls:C0860207Drug-Induced Liver Injury2CTD_human
umls:C1140680Malignant neoplasm of ovary2BeFree
umls:C1863119Dysalbuminemic Hyperthyroxinemia2BeFree
umls:C2919365Macroalbuminuric diabetic nephropathy2BeFree
umls:C0001430Adenoma1BeFree
umls:C0001925Albuminuria1RGD
umls:C0002793Anaplasia1BeFree
umls:C0002994Angioedema1CTD_human
umls:C0003123Anorexia1BeFree
umls:C0003460Anuria1CTD_human
umls:C0004364Autoimmune Diseases1BeFree
umls:C0005779Blood Coagulation Disorders1BeFree
umls:C0006111Brain Diseases1CTD_human
umls:C0006118Brain Neoplasms1BeFree
umls:C0006625Cachexia1BeFree
umls:C0007102Malignant tumor of colon1BeFree
umls:C0007121Bronchogenic Carcinoma1LHGDN
umls:C0007134Renal Cell Carcinoma1BeFree
umls:C0007786Brain Ischemia1CTD_human
umls:C0008031Chest Pain1LHGDN
umls:C0008312Primary biliary cirrhosis1BeFree
umls:C0010051Coronary Aneurysm1BeFree
umls:C0010308Congenital Hypothyroidism1BeFree
umls:C0010380Croup1BeFree
umls:C0011269Dementia, Vascular1BeFree
umls:C0011581Depressive disorder1CTD_human
umls:C0011615Dermatitis, Atopic1BeFree
umls:C0011875Diabetic Angiopathies1CTD_human
umls:C0011882Diabetic Neuropathies1BeFree
umls:C0012236DiGeorge Syndrome1BeFree
umls:C0013146Drug abuse1BeFree
umls:C0013338Pituitary dwarfism1BeFree
umls:C0013502Echinococcosis1CTD_human
umls:C0013595Eczema1BeFree
umls:C0014867Esophageal Varices1BeFree
umls:C0016059Fibrosis1CTD_human
umls:C0017662Glomerulonephritis, Membranoproliferative1CTD_human
umls:C0017667Nodular glomerulosclerosis1BeFree
umls:C0017668Focal glomerulosclerosis1BeFree
umls:C0018133Graft-vs-Host Disease1BeFree
umls:C0018378Guillain-Barre Syndrome1BeFree
umls:C0018799Heart Diseases1CTD_human
umls:C0018802Congestive heart failure1BeFree
umls:C0018995Hemochromatosis1BeFree
umls:C0019061Hemolytic-Uremic Syndrome1CTD_human
umls:C0019348Herpes Simplex Infections1BeFree
umls:C0019699HIV Seropositivity1CTD_human
umls:C0020179Huntington Disease1BeFree
umls:C0020445Hypercholesterolemia, Familial1BeFree
umls:C0020459Hyperinsulinism1BeFree
umls:C0020473Hyperlipidemia1RGD
umls:C0020474Hyperlipidemia, Familial Combined1BeFree
umls:C0020517Hypersensitivity1CTD_human
umls:C0020522Delayed Hypersensitivity1CTD_human
umls:C0020639Hypoproteinemia1RGD
umls:C0021053Immune System Diseases1BeFree
umls:C0021400Influenza1BeFree
umls:C0022548Keloid1CTD_human
umls:C0022806Kwashiorkor1BeFree
umls:C0023195Lecithin Acyltransferase Deficiency1BeFree
umls:C0023418leukemia1BeFree
umls:C0024291Lymphohistiocytosis, Hemophagocytic1BeFree
umls:C0024301Lymphoma, Follicular1BeFree
umls:C0026691Mucocutaneous Lymph Node Syndrome1BeFree
umls:C0026769Multiple Sclerosis1BeFree
umls:C0026780Mumps1BeFree
umls:C0026848Myopathy1CTD_human
umls:C0027055Myocardial Reperfusion Injury1CTD_human
umls:C0027719Nephrosclerosis1BeFree
umls:C0028797Occupational Diseases1CTD_human
umls:C0030193Pain1CTD_human
umls:C0030286Pancreatic Diseases1CTD_human
umls:C0030305Pancreatitis1CTD_human
umls:C0031039Pericardial effusion1BeFree
umls:C0031099Periodontitis1BeFree
umls:C0032002Pituitary Diseases1BeFree
umls:C0032131Plasmacytoma1BeFree
umls:C0032460Polycystic Ovary Syndrome1BeFree
umls:C0034065Pulmonary Embolism1LHGDN
umls:C0035126Reperfusion Injury1RGD
umls:C0035222Respiratory Distress Syndrome, Adult1CTD_human
umls:C0035242Respiratory Tract Diseases1CTD_human
umls:C0035457Rhinitis, Allergic, Perennial1CTD_human
umls:C0036572Seizures1BeFree
umls:C0038325Stevens-Johnson Syndrome1CTD_human
umls:C0038356Stomach Neoplasms1CTD_human
umls:C0038586Substance Use Disorders1BeFree
umls:C0040034Thrombocytopenia1CTD_human
umls:C0040128Thyroid Diseases1BeFree
umls:C0040435Tooth Diseases1BeFree
umls:C0041755Adverse reaction to drug1CTD_human
umls:C0042109Urticaria1CTD_human
umls:C0042164Uveitis1CTD_human
umls:C0042749Viremia1BeFree
umls:C0085580Essential Hypertension1BeFree
umls:C0085584Encephalopathies1BeFree
umls:C0085663Plasmacytosis1BeFree
umls:C0086981Sicca Syndrome1BeFree
umls:C0151744Myocardial Ischemia1BeFree
umls:C0152013Adenocarcinoma of lung (disorder)1CTD_human
umls:C0205851Germ cell tumor1BeFree
umls:C0206686Adrenocortical carcinoma1BeFree
umls:C0206734Hemangioblastoma1BeFree
umls:C0221002Hyperparathyroidism, Primary1BeFree
umls:C0235025Peripheral motor neuropathy1BeFree
umls:C0235833Congenital diaphragmatic hernia1BeFree
umls:C0238198Gastrointestinal Stromal Tumors1BeFree
umls:C0238339Hereditary pancreatitis1BeFree
umls:C0240035Interstitial fibrosis1BeFree
umls:C0242379Malignant neoplasm of lung1BeFree
umls:C0242383Age related macular degeneration1BeFree
umls:C0242488Acute Lung Injury1RGD
umls:C0259744dysproteinemia1BeFree
umls:C0259749Autonomic neuropathy1BeFree
umls:C0271650Impaired glucose tolerance1BeFree
umls:C0272051Xerocytosis1BeFree
umls:C0275524Coinfection1BeFree
umls:C0276622Acute viral hepatitis1BeFree
umls:C0280100Solid tumour1BeFree
umls:C0333186Restenosis1BeFree
umls:C0333463Senile Plaques1BeFree
umls:C0334524Mixed Germ Cell Tumor1BeFree
umls:C0338106Adenocarcinoma of colon1BeFree
umls:C0338656Impaired cognition1BeFree
umls:C0339467Proliferative retinopathy1BeFree
umls:C0342200Endemic Cretinism1BeFree
umls:C0342257Complications of Diabetes Mellitus1LHGDN
umls:C0342276Maturity onset diabetes mellitus in young1BeFree
umls:C0342613Danish type familial amyloid cardiomyopathy1BeFree
umls:C0346402Malignant neoplasm of adrenal cortex1BeFree
umls:C0393578Pallidoluysian degeneration1BeFree
umls:C0393799Miller Fisher Syndrome1BeFree
umls:C0398623Thrombophilia1BeFree
umls:C0403518Microalbuminuric diabetic nephropathy1BeFree
umls:C0442874Neuropathy1BeFree
umls:C0451641Urolithiasis1BeFree
umls:C0684249Carcinoma of lung1BeFree
umls:C0699790Colon Carcinoma1BeFree
umls:C0745103Hyperlipoproteinemia Type IIa1BeFree
umls:C0751781Dentatorubral-Pallidoluysian Atrophy1BeFree
umls:C0865274High-oxygen-affinity hemoglobin1BeFree
umls:C0948089Acute Coronary Syndrome1LHGDN
umls:C0993582Arthritis, Experimental1CTD_human
umls:C1096063Drug Resistant Epilepsy1BeFree
umls:C1112211Hepatic infection1BeFree
umls:C1260959Drusen1BeFree
umls:C1266090Hepatoid adenocarcinoma1BeFree
umls:C1274282Acral pseudolymphomatous angiokeratoma of children (APACHE)1BeFree
umls:C1298180Single tumor1BeFree
umls:C1318485Liver regeneration disorder1BeFree
umls:C1516490Cholangiolocellular Carcinoma1BeFree
umls:C1658953tumor vasculature1BeFree
umls:C1704321Nephrotic Syndrome, Minimal Change1BeFree
umls:C1704328Osteoblastic Osteosarcoma1BeFree
umls:C1704330Dental Diseases1BeFree
umls:C1704380Distal Renal Tubular Acidosis1BeFree
umls:C1709246Non-Neoplastic Disorder1BeFree
umls:C1709661Primary Focal Segmental Glomerulosclerosis1BeFree
umls:C1800706Idiopathic Pulmonary Fibrosis1BeFree
umls:C1840264IMMUNE SUPPRESSION1BeFree
umls:C1855796Hypoproteinemia, Hypercatabolic1BeFree
umls:C1959635Parvovirus B19 (disease)1BeFree
umls:C2349595Fetal anemia1BeFree
umls:C2931687Dysferlinopathy1BeFree
umls:C2936349Plaque, Amyloid1BeFree
umls:C3542021Duchenne and Becker Muscular Dystrophy1BeFree
umls:C3714619Insulin resistance syndrome1BeFree
umls:C3714796Isolated somatotropin deficiency1BeFree
umls:C0268345EHLERS-DANLOS SYNDROME, ARTHROCHALASIA TYPE0CLINVAR
umls:C0878666Analbuminemia0ORPHANET
umls:C1860228ZINC, ELEVATED PLASMA0CTD_human