TissGDB

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	TissGeneSummary
	TissGeneExp
	TissGene-miRNA
	TissGeneMut: TissGeneSNV, TissGeneCNV, and TissGeneFusions
	TissGeneNet
	TissGeneProg
	TissGeneClin: TissGeneDrug and TissGeneDisease

TissGeneSummary for F7

Gene summary

Basic gene information	Gene symbol	F7
	Gene name	coagulation factor VII (serum prothrombin conversion accelerator)
	Synonyms	SPCA
	Cytomap	UCSC genome browser: 13q34
	Type of gene	protein-coding
	RefGenes	NM_000131.4, NM_001267554.1,NM_019616.3,NR_051961.1,
	Description	FVII coagulation proteincoagulation factor VIIeptacog alfaproconvertin
	Modification date	20141207
dbXrefs	MIM : 613878
	HGNC : HGNC
	Ensembl : ENSG00000057593
	HPRD : 01965
	Vega : OTTHUMG00000017373
Protein	UniProt: go to UniProt's Cross Reference DB Table
Expression	CleanEX: HS_F7
	BioGPS: 2155
Pathway	NCI Pathway Interaction Database: F7
	KEGG: F7
	REACTOME: F7
	Pathway Commons: F7
Context	iHOP: F7
	ligand binding site mutation search in PubMed: F7
	UCL Cancer Institute: F7
Assigned class in TissGDB*	C
Included tissue-specific gene expression resources	HPA,GTEx
Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx)	Liver
Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA)	LIHC
Reference showing the relevant tissue of F7
Description by TissGene annotations	Cancer gene

* Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C.

Gene ontology having evidence of Inferred from Direct Assay (IDA) from Entrez

GO ID	GO term	PubMed ID
GO:0002690	positive regulation of leukocyte chemotaxis	17991872
GO:0010641	positive regulation of platelet-derived growth factor receptor signaling pathway	17991872
GO:0050927	positive regulation of positive chemotaxis	17991872
GO:0051897	positive regulation of protein kinase B signaling	18612547
GO:0002690	positive regulation of leukocyte chemotaxis	17991872
GO:0010641	positive regulation of platelet-derived growth factor receptor signaling pathway	17991872
GO:0050927	positive regulation of positive chemotaxis	17991872
GO:0051897	positive regulation of protein kinase B signaling	18612547

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TissGeneExp for F7

Gene expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1))
(TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16)

Gene isoform expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1))
(TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01)

Gene expressions across normal tissues of GTEx data
(GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct)
- Here, we shows the matched tissue types only among our 28 cancer types.

Different expressions across 14 cancer types with more than 10 samples between matched tumors and normals (X-axis: cancer type and Y-axis: log2(norm_counts+1))
(TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16)

- Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05)

Cancer type	Mean(exp) in tumor	Mean(exp) in matched normal	Log2FC	P-val.	FDR
BRCA	2.199766052	0.502668684	1.697097368	1.42E-10	5.54E-10
PRAD	-1.174195115	0.232737577	-1.406932692	1.84E-10	3.78E-09
LIHC	8.278334193	9.375018193	-1.096684	5.81E-06	2.60E-05
KIRC	-2.279112529	-0.091481974	-2.187630556	2.20E-20	1.80E-19
COAD	-0.421616269	-1.622593192	1.200976923	0.00419	0.010268781
KICH	1.775530193	-0.031181807	1.806712	0.00109	0.002352948
KIRP	-1.162971557	0.345153443	-1.508125	0.000119	0.000396431

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TissGene-miRNA for F7

Significantly anti-correlated miRNAs of TissGene across 28 cancer types
(Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016)
(TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21)
(TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16)
(Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25))

Cancer type

miRNA id

miRNA accession

P-val.

Coeff.

# samples

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TissGeneMut for F7

TissGeneSNV for F7

nsSNV counts per each loci.
Different colors of circles represent different cancer types. Circle size denotes number of samples.
(TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25)
* Click on the image to enlarge it in a new window.

Somatic nucleotide variants of TissGene across 28 cancer types
(X-axis: cancer type and Y-axis: % of mutated samples)
The numbers in parentheses are numbers of samples with mutation (nsSNVs).
(TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25)

- nsSNVs sorted by frequency.

AAchange	Cancer type	# samples
p.R364Q	HNSC	1
p.G222E	SKCM	1
p.R284W	LGG	1
p.G177W	HNSC	1
p.V336M	UVM	1
p.Q116H	CESC	1
p.D123E	LUAD	1
p.A304V	STAD	1
p.L273F	SKCM	1
p.G156D	STAD	1
p.R170C	LGG	1
p.P407Q	BLCA	1
p.A25S	SARC	1
p.G150R	SKCM	1
p.M282I	SKCM	1
p.L333M	STAD	1
p.S72C	ESCA	1
p.E325K	STAD	1
p.P207R	SKCM	1
p.A251V	STAD	1
p.G196X	THYM	1
p.E325K	BRCA	1
p.G157V	CHOL	1
p.R307H	LUAD	1
p.A266V	STAD	1
p.G184R	LUAD	1
p.G278R	PRAD	1
p.A251E	LUAD	1
p.D183H	BLCA	1
p.R364W	COAD	1
p.E330K	BLCA	1
p.G138E	SKCM	1
p.D277N	STAD	1
p.S207I	LUAD	1
p.V232M	SKCM	1
p.F328L	UCEC	1
p.E159Q	CESC	1
p.H408Y	LUSC	1
p.G157V	OV	1
p.A25T	THYM	1
p.R462P	LUSC	1
p.S396I	LUAD	1
p.P199L	STAD	1
p.G30R	STAD	1
p.R69W	COAD	1
p.V377M	SKCM	1
p.N361D	DLBC	1
p.G234R	SKCM	1
p.T419M	LUAD	1
p.S393L	SKCM	1
p.M366I	SKCM	1
p.T168N	LUAD	1
p.Q116H	BLCA	1
p.K259N	BLCA	1
p.T143M	THCA	1
p.P291R	SKCM	1
p.L189F	SKCM	1
p.A390T	STAD	1
p.V293M	SKCM	1
p.T59M	THCA	1
p.G184R	SKCM	1
p.T332M	BLCA	1
p.R413W	PRAD	1
p.N62S	SARC	1
p.H144Y	STAD	1
p.V148M	SKCM	1
p.A266T	UCEC	1
p.R86C	LGG	1
p.T332S	LUAD	1

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TissGeneCNV for F7

Copy number variations of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of CNV samples)
(TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16)

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TissGeneFusions for F7

Fusion genes including TissGene
(ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01)

Database	Src	Cancer type	Sample	Fusion gene	ORF	5'-gene BP	3'-gene BP
Chimerdb3.0	FusionScan	LUSC	TCGA-56-7823-01B	ATP11A-F7	Out-of-Frame	chr13:113439571	chr13:113768160

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TissGeneNet for F7

Co-expressed gene networks based on protein-protein interaction data (CePIN)
(TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16)
(PINA2 ppi data)

BRCA (tumor)	BRCA (normal)
F7, HNF4A, IKBKG, CEBPB, CEBPE, UIMC1, ALB, F3, BECN1, CEBPG, USP49, DMWD, RCHY1, F10, GGCX, F9, HPN (tumor)	F7, HNF4A, IKBKG, CEBPB, CEBPE, UIMC1, ALB, F3, BECN1, CEBPG, USP49, DMWD, RCHY1, F10, GGCX, F9, HPN (normal)

COAD (tumor)	COAD (normal)
F7, HNF4A, IKBKG, CEBPB, CEBPE, UIMC1, ALB, F3, BECN1, CEBPG, USP49, DMWD, RCHY1, F10, GGCX, F9, HPN (tumor)	F7, HNF4A, IKBKG, CEBPB, CEBPE, UIMC1, ALB, F3, BECN1, CEBPG, USP49, DMWD, RCHY1, F10, GGCX, F9, HPN (normal)

HNSC (tumor)	HNSC (normal)
F7, HNF4A, IKBKG, CEBPB, CEBPE, UIMC1, ALB, F3, BECN1, CEBPG, USP49, DMWD, RCHY1, F10, GGCX, F9, HPN (tumor)	F7, HNF4A, IKBKG, CEBPB, CEBPE, UIMC1, ALB, F3, BECN1, CEBPG, USP49, DMWD, RCHY1, F10, GGCX, F9, HPN (normal)

KICH (tumor)	KICH (normal)
F7, HNF4A, IKBKG, CEBPB, CEBPE, UIMC1, ALB, F3, BECN1, CEBPG, USP49, DMWD, RCHY1, F10, GGCX, F9, HPN (tumor)	F7, HNF4A, IKBKG, CEBPB, CEBPE, UIMC1, ALB, F3, BECN1, CEBPG, USP49, DMWD, RCHY1, F10, GGCX, F9, HPN (normal)

KIRC (tumor)	KIRC (normal)
F7, HNF4A, IKBKG, CEBPB, CEBPE, UIMC1, ALB, F3, BECN1, CEBPG, USP49, DMWD, RCHY1, F10, GGCX, F9, HPN (tumor)	F7, HNF4A, IKBKG, CEBPB, CEBPE, UIMC1, ALB, F3, BECN1, CEBPG, USP49, DMWD, RCHY1, F10, GGCX, F9, HPN (normal)

KIRP (tumor)	KIRP (normal)
F7, HNF4A, IKBKG, CEBPB, CEBPE, UIMC1, ALB, F3, BECN1, CEBPG, USP49, DMWD, RCHY1, F10, GGCX, F9, HPN (tumor)	F7, HNF4A, IKBKG, CEBPB, CEBPE, UIMC1, ALB, F3, BECN1, CEBPG, USP49, DMWD, RCHY1, F10, GGCX, F9, HPN (normal)

LIHC (tumor)	LIHC (normal)
F7, HNF4A, IKBKG, CEBPB, CEBPE, UIMC1, ALB, F3, BECN1, CEBPG, USP49, DMWD, RCHY1, F10, GGCX, F9, HPN (tumor)	F7, HNF4A, IKBKG, CEBPB, CEBPE, UIMC1, ALB, F3, BECN1, CEBPG, USP49, DMWD, RCHY1, F10, GGCX, F9, HPN (normal)

LUAD (tumor)	LUAD (normal)
F7, HNF4A, IKBKG, CEBPB, CEBPE, UIMC1, ALB, F3, BECN1, CEBPG, USP49, DMWD, RCHY1, F10, GGCX, F9, HPN (tumor)	F7, HNF4A, IKBKG, CEBPB, CEBPE, UIMC1, ALB, F3, BECN1, CEBPG, USP49, DMWD, RCHY1, F10, GGCX, F9, HPN (normal)

LUSC (tumor)	LUSC (normal)
F7, HNF4A, IKBKG, CEBPB, CEBPE, UIMC1, ALB, F3, BECN1, CEBPG, USP49, DMWD, RCHY1, F10, GGCX, F9, HPN (tumor)	F7, HNF4A, IKBKG, CEBPB, CEBPE, UIMC1, ALB, F3, BECN1, CEBPG, USP49, DMWD, RCHY1, F10, GGCX, F9, HPN (normal)

PRAD (tumor)	PRAD (normal)
F7, HNF4A, IKBKG, CEBPB, CEBPE, UIMC1, ALB, F3, BECN1, CEBPG, USP49, DMWD, RCHY1, F10, GGCX, F9, HPN (tumor)	F7, HNF4A, IKBKG, CEBPB, CEBPE, UIMC1, ALB, F3, BECN1, CEBPG, USP49, DMWD, RCHY1, F10, GGCX, F9, HPN (normal)

STAD (tumor)	STAD (normal)
F7, HNF4A, IKBKG, CEBPB, CEBPE, UIMC1, ALB, F3, BECN1, CEBPG, USP49, DMWD, RCHY1, F10, GGCX, F9, HPN (tumor)	F7, HNF4A, IKBKG, CEBPB, CEBPE, UIMC1, ALB, F3, BECN1, CEBPG, USP49, DMWD, RCHY1, F10, GGCX, F9, HPN (normal)

THCA (tumor)	THCA (normal)
F7, HNF4A, IKBKG, CEBPB, CEBPE, UIMC1, ALB, F3, BECN1, CEBPG, USP49, DMWD, RCHY1, F10, GGCX, F9, HPN (tumor)	F7, HNF4A, IKBKG, CEBPB, CEBPE, UIMC1, ALB, F3, BECN1, CEBPG, USP49, DMWD, RCHY1, F10, GGCX, F9, HPN (normal)

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TissGeneProg for F7

Kaplan-Meier plots with logrank tests of overall survival (OS) using 28 cancer types
(TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16)
(TCGA clinicalMatrix, phenotype data, version 2016-04-27)
* Click on the image to enlarge it in a new window.

Kaplan-Meier plots with logrank test of relapse free survival (RFS) using 28 cancer types
(TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16)
(TCGA clinicalMatrix, phenotype data, version 2016-04-27)
* Click on the image enlarge it in a new window.

Forest plot of Cox proportional hazard ratio (HR) and 95% CI of overall survival (OS) using 28 cancer types
(TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16)
(TCGA clinicalMatrix, phenotype data, version 2016-04-27)
* Click on the image enlarge it in a new window.

Forest plot of Cox proportional hazard ratio (HR) and 95% CI of relapse free survival (RFS) using 28 cancer types
(TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16)
(TCGA clinicalMatrix, phenotype data, version 2016-04-27)
* Click on the image enlarge it in a new window.

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TissGeneClin for F7

TissGeneDrug for F7

Drug information targeting TissGene
(DrugBank Version 5.0.6, 2017-04-01)

DrugBank ID	Drug name	Drug activity	Drug type	Drug status
DB00036	Coagulation factor VIIa Recombinant Human		Biotech	Approved

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TissGeneDisease for F7

Disease information associated with TissGene
(DisGeNet, 2016-06-01)

Disease ID	Disease name	# pubmeds	Source
umls:C0015503	Factor VII Deficiency	44	BeFree,CLINVAR,CTD_human,GAD,LHGDN,MGD,ORPHANET,UNIPROT
umls:C0010054	Coronary Arteriosclerosis	36	BeFree,GAD
umls:C0010068	Coronary heart disease	36	BeFree,GAD,LHGDN
umls:C0005779	Blood Coagulation Disorders	34	BeFree,GAD,LHGDN
umls:C0027051	Myocardial Infarction	34	BeFree,GAD,LHGDN
umls:C1956346	Coronary Artery Disease	22	BeFree,GAD
umls:C0151744	Myocardial Ischemia	21	BeFree,GAD
umls:C0007222	Cardiovascular Diseases	19	BeFree,GAD
umls:C0019069	Hemophilia A	16	BeFree,GAD
umls:C0038454	Cerebrovascular accident	13	BeFree,GAD,LHGDN
umls:C0684275	Hemophilia, NOS	12	BeFree
umls:C0004153	Atherosclerosis	8	BeFree,GAD,LHGDN
umls:C0011860	Diabetes Mellitus, Non-Insulin-Dependent	6	BeFree,GAD,RGD
umls:C0019080	Hemorrhage	6	CTD_human,GAD,LHGDN
umls:C0003850	Arteriosclerosis	5	BeFree
umls:C0008533	Hemophilia B	5	BeFree,GAD
umls:C0020538	Hypertensive disease	5	BeFree,GAD,LHGDN,RGD
umls:C0028754	Obesity	5	BeFree,GAD
umls:C0151699	Intracranial Hemorrhages	5	CTD_human
umls:C0155626	Acute myocardial infarction	5	BeFree
umls:C0948008	Ischemic stroke	5	BeFree,GAD
umls:C2239176	Liver carcinoma	5	BeFree
umls:C3272363	Ischemic Cerebrovascular Accident	5	BeFree
umls:C0006142	Malignant neoplasm of breast	4	BeFree
umls:C0007789	Cerebral Palsy	4	GAD
umls:C0019087	Hemorrhagic Disorders	4	BeFree,CTD_human,GAD
umls:C0027627	Neoplasm Metastasis	4	BeFree,LHGDN
umls:C0040038	Thromboembolism	4	BeFree,CTD_human,GAD
umls:C0042487	Venous Thrombosis	4	CTD_human,GAD
umls:C0151526	Premature Birth	4	GAD
umls:C0584960	Factor V Leiden mutation	4	BeFree
umls:C0678222	Breast Carcinoma	4	BeFree
umls:C0948089	Acute Coronary Syndrome	4	BeFree,GAD
umls:C1458155	Mammary Neoplasms	4	BeFree,LHGDN
umls:C2608079	WARFARIN SENSITIVITY (disorder)	4	BeFree,GAD
umls:C0007785	Cerebral Infarction	3	BeFree,GAD,LHGDN
umls:C0011849	Diabetes Mellitus	3	BeFree,RGD
umls:C0015519	Factor X Deficiency	3	BeFree
umls:C0021368	Inflammation	3	GAD,LHGDN
umls:C0022116	Ischemia	3	BeFree,RGD
umls:C0023903	Liver neoplasms	3	BeFree
umls:C0042974	von Willebrand Disease	3	BeFree
umls:C0151942	Arterial thrombosis	3	BeFree
umls:C0243026	Sepsis	3	BeFree,LHGDN,RGD
umls:C0272320	Hereditary factor VII deficiency disease	3	BeFree
umls:C1861172	Venous Thromboembolism	3	GAD,LHGDN
umls:C2937358	Cerebral Hemorrhage	3	CTD_human,GAD,LHGDN
umls:C0002895	Anemia, Sickle Cell	2	BeFree,GAD
umls:C0007786	Brain Ischemia	2	GAD
umls:C0009402	Colorectal Carcinoma	2	BeFree
umls:C0011853	Diabetes Mellitus, Experimental	2	RGD
umls:C0015523	Factor XI Deficiency	2	BeFree
umls:C0020473	Hyperlipidemia	2	BeFree,RGD
umls:C0023890	Liver Cirrhosis	2	BeFree
umls:C0023895	Liver diseases	2	BeFree
umls:C0040053	Thrombosis	2	GAD
umls:C0042880	Vitamin K Deficiency	2	BeFree,LHGDN
umls:C0149871	Deep Vein Thrombosis	2	BeFree,GAD
umls:C0242339	Dyslipidemias	2	BeFree
umls:C0398623	Thrombophilia	2	BeFree,GAD
umls:C0856761	Budd-Chiari Syndrome	2	GAD,RGD
umls:C1096116	Acquired haemophilia	2	BeFree
umls:C1527249	Colorectal Cancer	2	BeFree
umls:C1623038	Cirrhosis	2	BeFree
umls:C0000744	Abetalipoproteinemia	1	BeFree
umls:C0001815	Primary Myelofibrosis	1	BeFree
umls:C0002395	Alzheimer's Disease	1	GAD
umls:C0002736	Amyotrophic Lateral Sclerosis	1	GAD
umls:C0003130	Anoxia	1	LHGDN
umls:C0004238	Atrial Fibrillation	1	GAD,LHGDN
umls:C0006287	Bronchopulmonary Dysplasia	1	BeFree
umls:C0007102	Malignant tumor of colon	1	BeFree
umls:C0007282	Carotid Stenosis	1	GAD
umls:C0007820	Cerebrovascular Disorders	1	GAD
umls:C0008495	Chorioamnionitis	1	GAD
umls:C0009782	Connective Tissue Diseases	1	GAD
umls:C0010324	Crigler Najjar syndrome, type 1	1	BeFree
umls:C0011875	Diabetic Angiopathies	1	GAD
umls:C0012739	Disseminated Intravascular Coagulation	1	CTD_human
umls:C0013080	Down Syndrome	1	BeFree
umls:C0015929	Fetal Diseases	1	GAD
umls:C0015944	Fetal Membranes, Premature Rupture	1	GAD
umls:C0017327	Generalized atherosclerosis	1	GAD
umls:C0017638	Glioma	1	BeFree
umls:C0018965	Hematuria	1	CTD_human
umls:C0019158	Hepatitis	1	GAD
umls:C0020433	Hyperbilirubinemia	1	RGD
umls:C0020640	Inherited Factor II deficiency	1	RGD
umls:C0020676	Hypothyroidism	1	RGD
umls:C0021655	Insulin Resistance	1	GAD
umls:C0022658	Kidney Diseases	1	BeFree
umls:C0022661	Kidney Failure, Chronic	1	GAD
umls:C0022876	Premature Obstetric Labor	1	GAD
umls:C0023418	leukemia	1	BeFree
umls:C0025517	Metabolic Diseases	1	BeFree
umls:C0026827	Muscle hypotonia	1	BeFree
umls:C0026857	Musculoskeletal Diseases	1	GAD
umls:C0027660	Neoplasms, Glandular and Epithelial	1	RGD
umls:C0029925	Ovarian Carcinoma	1	BeFree
umls:C0031090	Periodontal Diseases	1	GAD
umls:C0032787	Postoperative Complications	1	CTD_human
umls:C0032914	Pre-Eclampsia	1	GAD
umls:C0032964	Pregnancy Complications, Hematologic	1	GAD
umls:C0036690	Septicemia	1	BeFree
umls:C0037274	Dermatologic disorders	1	GAD
umls:C0040028	Thrombocythemia, Essential	1	BeFree
umls:C0042373	Vascular Diseases	1	BeFree
umls:C0085096	Peripheral Vascular Diseases	1	BeFree,GAD,LHGDN
umls:C0085110	Severe Combined Immunodeficiency	1	BeFree
umls:C0149931	Migraine Disorders	1	BeFree,GAD
umls:C0162316	Iron deficiency anemia	1	BeFree
umls:C0232197	Fibrillation	1	BeFree
umls:C0242231	Coronary Stenosis	1	GAD
umls:C0263675	Chronic arthropathy	1	BeFree
umls:C0268542	Ornithine carbamoyltransferase deficiency	1	BeFree
umls:C0273058	Traumatic intracranial hemorrhage	1	CTD_human
umls:C0280100	Solid tumour	1	BeFree
umls:C0282666	Very Low Birth Weight	1	BeFree
umls:C0333186	Restenosis	1	GAD
umls:C0333203	Occlusive thrombus	1	BeFree
umls:C0340288	Stable angina	1	BeFree
umls:C0340708	Deep vein thrombosis of lower limb	1	BeFree
umls:C0341439	Chronic liver disease	1	BeFree,GAD
umls:C0342257	Complications of Diabetes Mellitus	1	GAD
umls:C0376358	Malignant neoplasm of prostate	1	BeFree
umls:C0518010	body mass	1	GAD
umls:C0553692	Brain hemorrhage	1	GAD
umls:C0577631	Carotid Atherosclerosis	1	BeFree
umls:C0598608	Hyperhomocysteinemia	1	BeFree
umls:C0600518	Choroidal Neovascularization	1	RGD
umls:C0687675	Pregnancy loss	1	GAD
umls:C0699790	Colon Carcinoma	1	BeFree
umls:C0699885	Carcinoma of bladder	1	BeFree
umls:C0749098	Hematoma, Subdural, Acute	1	CTD_human
umls:C0751956	Acute Cerebrovascular Accidents	1	BeFree
umls:C0752140	Intracranial Embolism	1	GAD
umls:C0810006	Acute cerebrovascular disease	1	BeFree
umls:C0948480	Coronary Restenosis	1	GAD
umls:C1140680	Malignant neoplasm of ovary	1	BeFree
umls:C1272641	Systemic arterial pressure	1	GAD
umls:C1519666	Tumor-Associated Vasculature	1	BeFree
umls:C1704436	Peripheral Arterial Diseases	1	BeFree
umls:C2919032	Infection of amniotic sac and membranes, unspecified, unspecified trimester, not applicable or unspecified	1	GAD
umls:C2936179	Obesity, Visceral	1	BeFree
umls:C3495426	Homocysteinemia	1	BeFree
umls:C3714514	Infection	1	GAD