 |
| |
| |
| |
| |
| |
| |
|
| TissGeneSummary for GATA6 |
 Gene summary |
| Basic gene information | Gene symbol | GATA6 |
| Gene name | GATA binding protein 6 | |
| Synonyms | - | |
| Cytomap | UCSC genome browser: 18q11.1-q11.2 | |
| Type of gene | protein-coding | |
| RefGenes | NM_005257.5, | |
| Description | GATA-binding factor 6transcription factor GATA-6 | |
| Modification date | 20141222 | |
| dbXrefs | MIM : 601656 | |
| HGNC : HGNC | ||
| Ensembl : ENSG00000141448 | ||
| HPRD : 09043 | ||
| Vega : OTTHUMG00000131767 | ||
| Protein | UniProt: go to UniProt's Cross Reference DB Table | |
| Expression | CleanEX: HS_GATA6 | |
| BioGPS: 2627 | ||
| Pathway | NCI Pathway Interaction Database: GATA6 | |
| KEGG: GATA6 | ||
| REACTOME: GATA6 | ||
| Pathway Commons: GATA6 | ||
| Context | iHOP: GATA6 | |
| ligand binding site mutation search in PubMed: GATA6 | ||
| UCL Cancer Institute: GATA6 | ||
| Assigned class in TissGDB* | C | |
| Included tissue-specific gene expression resources | TiGER,GTEx | |
| Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx) | OvaryStomach | |
| Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA) | OVSTAD | |
| Reference showing the relevant tissue of GATA6 | ||
| Description by TissGene annotations | Cancer gene Have significant anti-correlated miRNA | |
| * Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C. |
| Gene ontology having evidence of Inferred from Direct Assay (IDA) from Entrez |
| GO ID | GO term | PubMed ID | GO:0000122 | negative regulation of transcription from RNA polymerase II promoter | 18177748 | GO:0006366 | transcription from RNA polymerase II promoter | 19666519 | GO:0045766 | positive regulation of angiogenesis | 21127043 | GO:0045892 | negative regulation of transcription, DNA-templated | 18177748 | GO:0045944 | positive regulation of transcription from RNA polymerase II promoter | 19497978 | GO:0060575 | intestinal epithelial cell differentiation | 9566909 | GO:0070848 | response to growth factor | 21127043 | GO:0071158 | positive regulation of cell cycle arrest | 9593712 | GO:0071456 | cellular response to hypoxia | 21127043 | GO:0000122 | negative regulation of transcription from RNA polymerase II promoter | 18177748 | GO:0006366 | transcription from RNA polymerase II promoter | 19666519 | GO:0045766 | positive regulation of angiogenesis | 21127043 | GO:0045892 | negative regulation of transcription, DNA-templated | 18177748 | GO:0045944 | positive regulation of transcription from RNA polymerase II promoter | 19497978 | GO:0060575 | intestinal epithelial cell differentiation | 9566909 | GO:0070848 | response to growth factor | 21127043 | GO:0071158 | positive regulation of cell cycle arrest | 9593712 | GO:0071456 | cellular response to hypoxia | 21127043 |
| Top |
| TissGeneExp for GATA6 |
| Gene expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
 |
| Gene isoform expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01) |
 |
| Gene expressions across normal tissues of GTEx data (GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct) - Here, we shows the matched tissue types only among our 28 cancer types. |
 |
| Different expressions across 14 cancer types with more than 10 samples between matched tumors and normals (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
 |
| - Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05) |
| Cancer type | Mean(exp) in tumor | Mean(exp) in matched normal | Log2FC | P-val. | FDR |
| LUAD | 0.826845124 | 3.049833055 | -2.222987931 | 3.40E-20 | 7.13E-19 |
| LIHC | 1.351827055 | 2.430269055 | -1.078442 | 7.24E-09 | 6.51E-08 |
| BLCA | -0.516719577 | 2.446748844 | -2.963468421 | 3.48E-08 | 2.50E-06 |
| KICH | -2.343978945 | 0.147469055 | -2.491448 | 6.18E-07 | 2.41E-06 |
| LUSC | 0.022976192 | 2.957027173 | -2.93405098 | 8.69E-21 | 1.12E-19 |
| Top |
| TissGene-miRNA for GATA6 |
| Significantly anti-correlated miRNAs of TissGene across 28 cancer types (Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016) (TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21) (TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16) (Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25)) |
| Cancer type | miRNA id | miRNA accession | P-val. | Coeff. | # samples |
| UCS | hsa-miR-146b-5p | MIMAT0002809 | 0.04 | -0.28 | 56 |
| UVM | hsa-miR-30b-5p | MIMAT0000420 | 0.0041 | -0.32 | 80 |
| Top |
| TissGeneMut for GATA6 |
| TissGeneSNV for GATA6 |
| nsSNV counts per each loci. Different colors of circles represent different cancer types. Circle size denotes number of samples. (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) * Click on the image to enlarge it in a new window. |
 |
 |
| Somatic nucleotide variants of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of mutated samples) The numbers in parentheses are numbers of samples with mutation (nsSNVs). (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) |
 |
| - nsSNVs sorted by frequency. |
| AAchange | Cancer type | # samples |
| p.A459T | LUAD | 2 |
| p.M483T | OV | 1 |
| p.N529H | LUAD | 1 |
| p.P36L | SKCM | 1 |
| p.L118F | LUAD | 1 |
| p.G407D | LIHC | 1 |
| p.E579K | UCEC | 1 |
| p.A26D | LUAD | 1 |
| p.T503S | STAD | 1 |
| p.R479I | BLCA | 1 |
| p.A70E | LGG | 1 |
| p.R493Q | UCEC | 1 |
| p.Q143H | STAD | 1 |
| p.P516L | LUAD | 1 |
| p.N458Y | SKCM | 1 |
| p.F115L | STAD | 1 |
| p.Q143R | LGG | 1 |
| p.S573C | LUAD | 1 |
| p.N529K | GBM | 1 |
| p.C504* | UCEC | 1 |
| p.S520C | BLCA | 1 |
| p.E559Q | THCA | 1 |
| p.P399L | LIHC | 1 |
| p.A16D | LUAD | 1 |
| p.R456H | UCEC | 1 |
| p.A134G | LIHC | 1 |
| p.A57T | LGG | 1 |
| p.V584L | LUAD | 1 |
| p.G540R | SKCM | 1 |
| p.R493Q | GBM | 1 |
| p.M483I | SKCM | 1 |
| p.A578V | LUSC | 1 |
| p.M483I | BLCA | 1 |
| p.S576L | LIHC | 1 |
| p.S523* | HNSC | 1 |
| p.Y148N | LGG | 1 |
| p.S583Y | BLCA | 1 |
| p.S588F | SKCM | 1 |
| p.G158S | LUAD | 1 |
| Top |
| TissGeneCNV for GATA6 |
| Copy number variations of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of CNV samples) (TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16) |
 |
| Top |
| TissGeneFusions for GATA6 |
| Fusion genes including TissGene (ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01) |
| Database | Src | Cancer type | Sample | Fusion gene | ORF | 5'-gene BP | 3'-gene BP |
| Chimerdb3.0 | ChiTaRs | NA | AW015488 | GATA6-TBL1Y | chr18:19757201 | chrY:6887705 | |
| TCGAfusionPortal | PRADA | LUAD | TCGA-44-A47G-01A | ROCK1-GATA6 | In-frame | Chr18:18690779 | Chr18:19780619 |
| Top |
| TissGeneNet for GATA6 |
| Co-expressed gene networks based on protein-protein interaction data (CePIN) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (PINA2 ppi data) |
| BRCA (tumor) | BRCA (normal) |
| GATA6, HNF4A, SP1, CDK9, EP300, NKX2-1, CRIP2, MED1, CYB5A, MUC4, NOX1, HAMP, TFF2, KPNA3, KLF2 (tumor) | GATA6, HNF4A, SP1, CDK9, EP300, NKX2-1, CRIP2, MED1, CYB5A, MUC4, NOX1, HAMP, TFF2, KPNA3, KLF2 (normal) |
 |  |
| COAD (tumor) | COAD (normal) |
| GATA6, HNF4A, SP1, CDK9, EP300, NKX2-1, CRIP2, MED1, CYB5A, MUC4, NOX1, HAMP, TFF2, KPNA3, KLF2 (tumor) | GATA6, HNF4A, SP1, CDK9, EP300, NKX2-1, CRIP2, MED1, CYB5A, MUC4, NOX1, HAMP, TFF2, KPNA3, KLF2 (normal) |
 |  |
| HNSC (tumor) | HNSC (normal) |
| GATA6, HNF4A, SP1, CDK9, EP300, NKX2-1, CRIP2, MED1, CYB5A, MUC4, NOX1, HAMP, TFF2, KPNA3, KLF2 (tumor) | GATA6, HNF4A, SP1, CDK9, EP300, NKX2-1, CRIP2, MED1, CYB5A, MUC4, NOX1, HAMP, TFF2, KPNA3, KLF2 (normal) |
 |  |
| KICH (tumor) | KICH (normal) |
| GATA6, HNF4A, SP1, CDK9, EP300, NKX2-1, CRIP2, MED1, CYB5A, MUC4, NOX1, HAMP, TFF2, KPNA3, KLF2 (tumor) | GATA6, HNF4A, SP1, CDK9, EP300, NKX2-1, CRIP2, MED1, CYB5A, MUC4, NOX1, HAMP, TFF2, KPNA3, KLF2 (normal) |
 |  |
| KIRC (tumor) | KIRC (normal) |
| GATA6, HNF4A, SP1, CDK9, EP300, NKX2-1, CRIP2, MED1, CYB5A, MUC4, NOX1, HAMP, TFF2, KPNA3, KLF2 (tumor) | GATA6, HNF4A, SP1, CDK9, EP300, NKX2-1, CRIP2, MED1, CYB5A, MUC4, NOX1, HAMP, TFF2, KPNA3, KLF2 (normal) |
 |  |
| KIRP (tumor) | KIRP (normal) |
| GATA6, HNF4A, SP1, CDK9, EP300, NKX2-1, CRIP2, MED1, CYB5A, MUC4, NOX1, HAMP, TFF2, KPNA3, KLF2 (tumor) | GATA6, HNF4A, SP1, CDK9, EP300, NKX2-1, CRIP2, MED1, CYB5A, MUC4, NOX1, HAMP, TFF2, KPNA3, KLF2 (normal) |
 |  |
| LIHC (tumor) | LIHC (normal) |
| GATA6, HNF4A, SP1, CDK9, EP300, NKX2-1, CRIP2, MED1, CYB5A, MUC4, NOX1, HAMP, TFF2, KPNA3, KLF2 (tumor) | GATA6, HNF4A, SP1, CDK9, EP300, NKX2-1, CRIP2, MED1, CYB5A, MUC4, NOX1, HAMP, TFF2, KPNA3, KLF2 (normal) |
 |  |
| LUAD (tumor) | LUAD (normal) |
| GATA6, HNF4A, SP1, CDK9, EP300, NKX2-1, CRIP2, MED1, CYB5A, MUC4, NOX1, HAMP, TFF2, KPNA3, KLF2 (tumor) | GATA6, HNF4A, SP1, CDK9, EP300, NKX2-1, CRIP2, MED1, CYB5A, MUC4, NOX1, HAMP, TFF2, KPNA3, KLF2 (normal) |
 |  |
| LUSC (tumor) | LUSC (normal) |
| GATA6, HNF4A, SP1, CDK9, EP300, NKX2-1, CRIP2, MED1, CYB5A, MUC4, NOX1, HAMP, TFF2, KPNA3, KLF2 (tumor) | GATA6, HNF4A, SP1, CDK9, EP300, NKX2-1, CRIP2, MED1, CYB5A, MUC4, NOX1, HAMP, TFF2, KPNA3, KLF2 (normal) |
 |  |
| PRAD (tumor) | PRAD (normal) |
| GATA6, HNF4A, SP1, CDK9, EP300, NKX2-1, CRIP2, MED1, CYB5A, MUC4, NOX1, HAMP, TFF2, KPNA3, KLF2 (tumor) | GATA6, HNF4A, SP1, CDK9, EP300, NKX2-1, CRIP2, MED1, CYB5A, MUC4, NOX1, HAMP, TFF2, KPNA3, KLF2 (normal) |
 |  |
| STAD (tumor) | STAD (normal) |
| GATA6, HNF4A, SP1, CDK9, EP300, NKX2-1, CRIP2, MED1, CYB5A, MUC4, NOX1, HAMP, TFF2, KPNA3, KLF2 (tumor) | GATA6, HNF4A, SP1, CDK9, EP300, NKX2-1, CRIP2, MED1, CYB5A, MUC4, NOX1, HAMP, TFF2, KPNA3, KLF2 (normal) |
 |  |
| THCA (tumor) | THCA (normal) |
| GATA6, HNF4A, SP1, CDK9, EP300, NKX2-1, CRIP2, MED1, CYB5A, MUC4, NOX1, HAMP, TFF2, KPNA3, KLF2 (tumor) | GATA6, HNF4A, SP1, CDK9, EP300, NKX2-1, CRIP2, MED1, CYB5A, MUC4, NOX1, HAMP, TFF2, KPNA3, KLF2 (normal) |
 |  |
| Top |
| TissGeneProg for GATA6 |
| Kaplan-Meier plots with logrank tests of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image to enlarge it in a new window. |
 |
| Kaplan-Meier plots with logrank test of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
 |
| Forest plot of Cox proportional hazard ratio (HR) and 95% CI of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
 |
| Forest plot of Cox proportional hazard ratio (HR) and 95% CI of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
 |
| Top |
| TissGeneClin for GATA6 |
| TissGeneDrug for GATA6 |
| Drug information targeting TissGene (DrugBank Version 5.0.6, 2017-04-01) |
| DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Top |
| TissGeneDisease for GATA6 |
| Disease information associated with TissGene (DisGeNet, 2016-06-01) |
| Disease ID | Disease name | # pubmeds | Source |
| umls:C0596263 | Carcinogenesis | 8 | BeFree |
| umls:C0018798 | Congenital Heart Defects | 7 | BeFree,GAD |
| umls:C0024623 | Malignant neoplasm of stomach | 5 | BeFree |
| umls:C0152021 | Congenital heart disease | 5 | BeFree |
| umls:C0699791 | Stomach Carcinoma | 5 | BeFree |
| umls:C0000768 | Congenital Abnormality | 4 | BeFree |
| umls:C0009402 | Colorectal Carcinoma | 4 | BeFree |
| umls:C0010068 | Coronary heart disease | 4 | BeFree |
| umls:C0011847 | Diabetes | 4 | BeFree |
| umls:C0011849 | Diabetes Mellitus | 4 | BeFree |
| umls:C0027627 | Neoplasm Metastasis | 4 | BeFree |
| umls:C0039685 | Tetralogy of Fallot | 4 | BeFree,CLINVAR,GAD,ORPHANET,UNIPROT |
| umls:C0235974 | Pancreatic carcinoma | 4 | BeFree |
| umls:C0346647 | Malignant neoplasm of pancreas | 4 | BeFree |
| umls:C0699790 | Colon Carcinoma | 4 | BeFree |
| umls:C1527249 | Colorectal Cancer | 4 | BeFree |
| umls:C0001418 | Adenocarcinoma | 3 | BeFree |
| umls:C0001430 | Adenoma | 3 | BeFree |
| umls:C0007102 | Malignant tumor of colon | 3 | BeFree |
| umls:C0018818 | Ventricular Septal Defects | 3 | BeFree |
| umls:C0029928 | Ovarian Diseases | 3 | BeFree |
| umls:C0041207 | Truncus Arteriosus, Persistent | 3 | BeFree,CLINVAR |
| umls:C0158981 | Neonatal diabetes mellitus | 3 | BeFree |
| umls:C0206686 | Adrenocortical carcinoma | 3 | BeFree |
| umls:C1140680 | Malignant neoplasm of ovary | 3 | BeFree,GAD |
| umls:C0002793 | Anaplasia | 2 | BeFree |
| umls:C0029925 | Ovarian Carcinoma | 2 | BeFree |
| umls:C0032460 | Polycystic Ovary Syndrome | 2 | BeFree,LHGDN |
| umls:C0205851 | Germ cell tumor | 2 | BeFree |
| umls:C0232197 | Fibrillation | 2 | BeFree |
| umls:C0267963 | Exocrine pancreatic insufficiency | 2 | BeFree |
| umls:C0919267 | ovarian neoplasm | 2 | BeFree |
| umls:C1704272 | Benign Prostatic Hyperplasia | 2 | BeFree |
| umls:C0001624 | Adrenal Gland Neoplasms | 1 | BeFree |
| umls:C0004114 | Astrocytoma | 1 | BeFree |
| umls:C0005694 | Bladder neck obstruction | 1 | BeFree |
| umls:C0006142 | Malignant neoplasm of breast | 1 | BeFree |
| umls:C0007138 | Carcinoma, Transitional Cell | 1 | BeFree |
| umls:C0007193 | Cardiomyopathy, Dilated | 1 | BeFree |
| umls:C0010346 | Crohn Disease | 1 | GAD |
| umls:C0011860 | Diabetes Mellitus, Non-Insulin-Dependent | 1 | BeFree |
| umls:C0014145 | Yolk Sac Tumor | 1 | BeFree,LHGDN |
| umls:C0014175 | Endometriosis | 1 | BeFree |
| umls:C0017152 | Gastritis | 1 | BeFree |
| umls:C0017636 | Glioblastoma | 1 | BeFree |
| umls:C0017638 | Glioma | 1 | BeFree |
| umls:C0018816 | Heart Septal Defects | 1 | BeFree |
| umls:C0018817 | Atrial Septal Defects | 1 | BeFree,GAD |
| umls:C0019284 | Diaphragmatic Hernia | 1 | CTD_human |
| umls:C0020542 | Pulmonary Hypertension | 1 | RGD |
| umls:C0021390 | Inflammatory Bowel Diseases | 1 | GAD |
| umls:C0023903 | Liver neoplasms | 1 | BeFree |
| umls:C0024121 | Lung Neoplasms | 1 | CTD_human |
| umls:C0030297 | Pancreatic Neoplasm | 1 | LHGDN |
| umls:C0036421 | Systemic Scleroderma | 1 | BeFree |
| umls:C0036920 | Sezary Syndrome | 1 | BeFree |
| umls:C0038356 | Stomach Neoplasms | 1 | LHGDN |
| umls:C0039538 | Teratoma | 1 | BeFree,LHGDN |
| umls:C0039747 | Thecoma | 1 | BeFree |
| umls:C0085786 | Hamman-Rich syndrome | 1 | BeFree |
| umls:C0149782 | Squamous cell carcinoma of lung | 1 | BeFree |
| umls:C0152013 | Adenocarcinoma of lung (disorder) | 1 | BeFree |
| umls:C0152171 | Idiopathic pulmonary hypertension | 1 | BeFree |
| umls:C0206667 | Adrenal Cortical Adenoma | 1 | BeFree |
| umls:C0206698 | Cholangiocarcinoma | 1 | BeFree |
| umls:C0235833 | Congenital diaphragmatic hernia | 1 | BeFree,ORPHANET |
| umls:C0242379 | Malignant neoplasm of lung | 1 | BeFree |
| umls:C0268855 | Hypertrophy of bladder | 1 | BeFree |
| umls:C0281361 | Adenocarcinoma of pancreas | 1 | BeFree |
| umls:C0334520 | Teratoma, Malignant | 1 | BeFree |
| umls:C0334579 | Anaplastic astrocytoma | 1 | BeFree |
| umls:C0340427 | Familial dilated cardiomyopathy | 1 | BeFree |
| umls:C0574785 | Lower Urinary Tract Symptoms | 1 | BeFree |
| umls:C0678222 | Breast Carcinoma | 1 | BeFree |
| umls:C0686619 | Secondary malignant neoplasm of lymph node | 1 | BeFree |
| umls:C0850572 | Adenomatous polyp of colon | 1 | BeFree |
| umls:C0949059 | Polyp of large intestine | 1 | BeFree |
| umls:C1258085 | Barrett Epithelium | 1 | BeFree |
| umls:C1301034 | Pancreatic intraepithelial neoplasia | 1 | BeFree |
| umls:C1335302 | Pancreatic Ductal Adenocarcinoma | 1 | BeFree |
| umls:C1800706 | Idiopathic Pulmonary Fibrosis | 1 | BeFree |
| umls:C1838780 | Pancreatic Hypoplasia, Congenital, with Diabetes Mellitus and Congenital Heart Disease | 1 | BeFree,CLINVAR |
| umls:C1857586 | CONOTRUNCAL HEART MALFORMATIONS (disorder) | 1 | UNIPROT |
| umls:C2973725 | Pulmonary arterial hypertension | 1 | BeFree |
| umls:C3280939 | ATRIOVENTRICULAR SEPTAL DEFECT 5 | 1 | CLINVAR,UNIPROT |
| umls:C3280943 | ATRIAL SEPTAL DEFECT 9 | 1 | CLINVAR,UNIPROT |
| umls:C3714844 | Pulmonary Hypertension, Primary, 1, With Hereditary Hemorrhagic Telangiectasia | 1 | BeFree |
| umls:C4012454 | HEART DEFECTS, CONGENITAL, AND OTHER CONGENITAL ANOMALIES | 1 | UNIPROT |
| umls:C0344724 | Ostium secundum atrial septal defect | 0 | ORPHANET |
| umls:C0344735 | Partial atrioventricular canal | 0 | ORPHANET |
| umls:C2931296 | Yorifuji Okuno syndrome | 0 | ORPHANET |
Copyright 2016-Present - The University of Texas Health Science Center at Houston (UTHealth) Web File Viewing | How to Report, Fraud, Waste and Abuse | State of Texas | Statewide Search | Texas Homeland Security | Site Policies |